Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 819437..819953 Replicon chromosome
Accession NZ_CP084692
Organism Enterobacter mori strain BC01

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag K6742_RS03720 Protein ID WP_120159597.1
Coordinates 819437..819721 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag K6742_RS03725 Protein ID WP_212474435.1
Coordinates 819711..819953 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6742_RS03705 (K6742_03705) 814683..816326 + 1644 WP_214594741.1 alpha,alpha-phosphotrehalase -
K6742_RS03710 (K6742_03710) 816702..818840 + 2139 WP_047646505.1 anaerobic ribonucleoside-triphosphate reductase -
K6742_RS03715 (K6742_03715) 818969..819433 + 465 WP_214594740.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
K6742_RS03720 (K6742_03720) 819437..819721 - 285 WP_120159597.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
K6742_RS03725 (K6742_03725) 819711..819953 - 243 WP_212474435.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
K6742_RS03730 (K6742_03730) 820031..821941 - 1911 WP_226347956.1 PRD domain-containing protein -
K6742_RS03735 (K6742_03735) 821961..823097 - 1137 WP_214594739.1 lactonase family protein -
K6742_RS03740 (K6742_03740) 823217..823957 - 741 WP_024907273.1 KDGP aldolase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-83)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-65)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10878.69 Da        Isoelectric Point: 10.1988

>T219155 WP_120159597.1 NZ_CP084692:c819721-819437 [Enterobacter mori]
MTYELAFDPRALKEWSKLGETVKDQFKKKLADVLVNPRVESARLHGLPDCYKIKLRSQGYRLVYQVQDNVVTVFVIAIGK
REKAAVYHDANKRL

Download         Length: 285 bp

>T219155 NZ_CP116191:c2838891-2838640 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTCATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGTTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACGGAAAAGGAC
ATTATTGAGTGA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8986.40 Da        Isoelectric Point: 5.0941

>AT219155 WP_212474435.1 NZ_CP084692:c819953-819711 [Enterobacter mori]
MATLNVRLDDKLKNEAYAVLEKLNITPTEAVRLLFQYVAETGRMPVKTVTISDSEDELIKAVRDRLANPQKGIKVSLDDL

Download         Length: 243 bp

>AT219155 NZ_CP116191:c2838643-2838389 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAAATTATCAAAGATACACGCAGAACACCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GCTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References