Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) KacT-ataR/DUF1778(antitoxin)
Location 735169..735963 Replicon chromosome
Accession NZ_CP084692
Organism Enterobacter mori strain BC01

Toxin (Protein)


Gene name KacT Uniprot ID -
Locus tag K6742_RS03340 Protein ID WP_214594787.1
Coordinates 735442..735963 (+) Length 174 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag K6742_RS03335 Protein ID WP_010427238.1
Coordinates 735169..735438 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6742_RS03310 (K6742_03310) 731118..732194 - 1077 WP_042717330.1 DUF2955 domain-containing protein -
K6742_RS03315 (K6742_03315) 732184..733251 - 1068 WP_214594867.1 HlyD family secretion protein -
K6742_RS03320 (K6742_03320) 733248..733718 - 471 WP_174341109.1 MarR family transcriptional regulator -
K6742_RS03325 (K6742_03325) 733865..734560 - 696 WP_226347935.1 winged helix-turn-helix domain-containing protein -
K6742_RS03330 (K6742_03330) 734629..734952 - 324 WP_214594788.1 antibiotic biosynthesis monooxygenase -
K6742_RS03335 (K6742_03335) 735169..735438 + 270 WP_010427238.1 DUF1778 domain-containing protein Antitoxin
K6742_RS03340 (K6742_03340) 735442..735963 + 522 WP_214594787.1 GNAT family N-acetyltransferase Toxin
K6742_RS03345 (K6742_03345) 736015..737430 - 1416 WP_214594786.1 aldehyde dehydrogenase family protein -
K6742_RS03350 (K6742_03350) 737531..738433 + 903 WP_214594785.1 LysR family transcriptional regulator -
K6742_RS03355 (K6742_03355) 738420..738899 - 480 WP_010427243.1 carboxymuconolactone decarboxylase family protein -
K6742_RS03360 (K6742_03360) 739003..740391 + 1389 WP_226347936.1 PLP-dependent aminotransferase family protein -
K6742_RS03365 (K6742_03365) 740478..740639 - 162 WP_023334364.1 DUF1127 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(88-150)

Antitoxin

Vibrio phage ICP1, Orf50

(3-85)


Sequences

Toxin        


Download         Length: 174 a.a.        Molecular weight: 19847.97 Da        Isoelectric Point: 9.1715

>T219154 WP_214594787.1 NZ_CP084692:735442-735963 [Enterobacter mori]
VNDVKIGIFSEDVEYDLSQFDCGEESLNTFLTEYLKRQHRGKFLRGYVLTTRETKPRILGYYTLSGSCFEKAYLPSKTQQ
KRIPYKNVPSVTLGRLAIDKRIQGQGYGELLVIHAMKTVYLASFAVGIHGLFVEALNHKAKDFYLKMGFIPLLAENAFTL
FLPTKTFERVFEE

Download         Length: 522 bp

>T219154 NZ_CP116191:c2838643-2838389 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAAATTATCAAAGATACACGCAGAACACCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GCTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 10043.43 Da        Isoelectric Point: 5.1171

>AT219154 WP_010427238.1 NZ_CP084692:735169-735438 [Enterobacter mori]
MSALKKQRIDLRLTEDDKNMIEEAAAMTNQSISQFMVSTASERAAEVIDQHRRLVLSEASWNTVMDAISNPPAPNDRLKQ
AAKRLLDME

Download         Length: 270 bp

>AT219154 NZ_CP116191:c2838891-2838640 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTCATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGTTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACGGAAAAGGAC
ATTATTGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References