Detailed information of TA system TA219108

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/Cpta(toxin)
• Location: 3182050..3182710
• Replicon: chromosome
• Accession: NZ_CP084656
• Organism: Pectobacterium versatile strain SR1

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: LGL96_RS14175
• Protein ID: WP_103861404.1
• Coordinates: 3182297..3182710 (+)
• Length: 138 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: A0A1V2R9A9
• Locus tag: LGL96_RS14170
• Protein ID: WP_039355397.1
• Coordinates: 3182050..3182316 (+)
• Length: 89 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LGL96_RS14150 (LGL96_14150)	3177952..3178956	-	1005	WP_103941892.1	substrate-binding domain-containing protein	-
LGL96_RS14155 (LGL96_14155)	3179011..3179619	-	609	WP_095701613.1	HD domain-containing protein	-
LGL96_RS14160 (LGL96_14160)	3179898..3180545	+	648	WP_225586057.1	hemolysin III family protein	-
LGL96_RS14165 (LGL96_14165)	3180813..3181814	-	1002	WP_225586056.1	tRNA-modifying protein YgfZ	-
LGL96_RS14170 (LGL96_14170)	3182050..3182316	+	267	WP_039355397.1	FAD assembly factor SdhE	Antitoxin
LGL96_RS14175 (LGL96_14175)	3182297..3182710	+	414	WP_103861404.1	protein YgfX	Toxin
LGL96_RS14180 (LGL96_14180)	3182779..3183714	+	936	WP_103861403.1	23S rRNA (adenine(1618)-N(6))-methyltransferase RlmF	-
LGL96_RS14185 (LGL96_14185)	3183780..3184103	-	324	WP_010301820.1	hypothetical protein	-
LGL96_RS14190 (LGL96_14190)	3184132..3184650	-	519	WP_044204035.1	flavodoxin FldB	-
LGL96_RS14195 (LGL96_14195)	3184992..3185378	-	387	WP_211025878.1	thioesterase family protein	-
LGL96_RS14200 (LGL96_14200)	3185603..3186931	-	1329	WP_103861399.1	MFS transporter	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Inner membrane protein YgfX (2-132)

Antitoxin

• Flavinator of succinate dehydrogenase (8-79)

Sequences

Toxin

Protein

• Length: 138 a.a.
• Molecular weight: 16359.31 Da
• Isoelectric Point: 10.7911

>T219108 WP_103861404.1 NZ_CP084656:3182297-3182710 [Pectobacterium versatile]
VAQWRCDLRVSWRMQLLSLVVHGLLVLFILLAPWPDGYAWLWLCLVTMVMFGFIRSQRNIKSRQGEIVLLSETTLNWRQQ
EWQIVKRPWLLKNGVLLSLQAVNAKDKQQLWLASDSMGDDEWRHLRQLLLQQKHWAR

Nucleotide

• Length: 414 bp

>T219108 NZ_CP116181:c4051984-4051700 [Escherichia coli]
ATGCAATTTACGGTATACCGCAGTCGCGGCAGGAACGCCGCGTTTCCCTTTGTTATTGATGTTACCAGCGACATTATTGG
TGAGATTAATCGCCGTATCGTTATTCCATTAACACCTATTGAACGATTTAGCCGTATTCGCCCACCAGAACGGCTTAACC
CAATCCTTTTACTGATAGACGGCAAAGAATATGTGCTCATGACGCATGAGACTGCAACTGTTCCAGTTAACGCGCTGGGA
ACGAAATTTTGCGATGCCAGCGCGCACCGAACGTTGATTAAATGA

Antitoxin

Protein

• Length: 89 a.a.
• Molecular weight: 10506.99 Da
• Isoelectric Point: 6.2223

>AT219108 WP_039355397.1 NZ_CP084656:3182050-3182316 [Pectobacterium versatile]
MEIDNKSRIHWACRRGMRELDIAIMPFFEHDYDTLNDTDKRTFVRLLQSDDPDLFNWLMNHGEPKDGELKRMISLIQTRN
KDRGPVAM

Nucleotide

• Length: 267 bp

>AT219108 NZ_CP116181:c4052220-4051987 [Escherichia coli]
ATGACTGCAAAACGTACCACACAAAGTGTGACCGTCACCGTCGACCGTGAGTTAGTCAATCGCGCTCGTGATGCAGGCTT
AAATATGAGCGCCACCCTTACGGTTGCGCTCAATGCTGAACTTAAAAAACATGCAGCAACACGTTGGCGTGAAGAGAACG
CAGAAGCTATCGCTGCGTTAAATCAATTGGCTGATGAAACCGGATGTTTCTCTGATGAGTACCGGAGCTTCTAG

Structures

Antitoxin

• AlphaFold DB: A0A1V2R9A9