Detailed information of TA system TA219106

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-parE/ParE-RHH
• Location: 2958202..2958785
• Replicon: chromosome
• Accession: NZ_CP084656
• Organism: Pectobacterium versatile strain SR1

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: LGL96_RS13145
• Protein ID: WP_130621282.1
• Coordinates: 2958480..2958785 (+)
• Length: 102 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A7V8PT23
• Locus tag: LGL96_RS13140
• Protein ID: WP_010296210.1
• Coordinates: 2958202..2958492 (+)
• Length: 97 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LGL96_RS13120 (LGL96_13120)	2953336..2954598	-	1263	WP_103861534.1	L-rhamnose isomerase	-
LGL96_RS13125 (LGL96_13125)	2954595..2956085	-	1491	WP_225586351.1	rhamnulokinase	-
LGL96_RS13130 (LGL96_13130)	2956422..2957261	+	840	WP_039493893.1	HTH-type transcriptional activator RhaS	-
LGL96_RS13135 (LGL96_13135)	2957286..2958140	+	855	WP_040031929.1	helix-turn-helix domain-containing protein	-
LGL96_RS13140 (LGL96_13140)	2958202..2958492	+	291	WP_010296210.1	ribbon-helix-helix protein, CopG family	Antitoxin
LGL96_RS13145 (LGL96_13145)	2958480..2958785	+	306	WP_130621282.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
LGL96_RS13150 (LGL96_13150)	2958905..2960611	-	1707	WP_225586352.1	ABC transporter ATP-binding protein	-
LGL96_RS13155 (LGL96_13155)	2960608..2961474	-	867	WP_125232223.1	ABC transporter permease	-
LGL96_RS13160 (LGL96_13160)	2961467..2962426	-	960	WP_029367586.1	ABC transporter permease	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-96)

Antitoxin

• Ribbon-helix-helix protein, CopG (9-46)

Sequences

Toxin

Protein

• Length: 102 a.a.
• Molecular weight: 11588.49 Da
• Isoelectric Point: 9.8325

>T219106 WP_130621282.1 NZ_CP084656:2958480-2958785 [Pectobacterium versatile]
MPQVIVSERARRDLQRLQDFLKNKNALAAKKAAEVLIRGIRQLEALPNIGRPVEHLPLEYQELVIEFGSSGYVMLYRHDE
LIGRVVILTVKHQKEAGYQNP

Nucleotide

• Length: 306 bp

>T219106 NZ_CP116181:3600411-3600629 [Escherichia coli]
ATGTCCGAAAAACCTTTAACGAAAACCGATTATTTAATGCGTTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGTGT
TATCGAGAAAAATAAATACGAATTATCAGATAATGAACTGGCGGTATTTTACTCAGCCGCAGATCACCGCCTCGCCGAAT
TGACCATGAATAAACTGTACGACAAGATCCCTTCCTCAGTATGGAAATTTATTCGCTAA

Antitoxin

Protein

• Length: 97 a.a.
• Molecular weight: 11064.13 Da
• Isoelectric Point: 4.7692

>AT219106 WP_010296210.1 NZ_CP084656:2958202-2958492 [Pectobacterium versatile]
MADTTRQTTTLRIDQDIKERLKTLADDRNSSAHALMLEAIAEYVEREEKRSQYRKEALAAWEDYQDTGKHITADETVTWL
ESWGSGHEQDAPACHK

Nucleotide

• Length: 291 bp

>AT219106 NZ_CP116181:3600011-3600385 [Escherichia coli]
ATGGATGAATACTCACCCAAAAGACATGATATCGCACAGCTTAAGTTTCTCTGTGAAACCCTGTATCATGACTGCCTTGC
AAACCTTGAAGAAAGCAATCATGGCTGGGTTAACGACCCAACCTCGGCGATCAACCTCCAGTTGAATGAACTGATTGAGC
ATATTGCGACCTTCGCACTTAATTACAAAATTAAGTATAATGAAGACAATAAGCTCATTGAGCAGATCGACGAATATCTG
GATGACACCTTTATGTTGTTCAGTAGTTATGGTATTAATATGCAGGATCTTCAGAAATGGCGGAAGTCAGGTAATCGACT
ATTCCGTTGTTTTGTCAATGCGACGAAAGAGAATCCTGCGAGTTTATCTTGTTAG

Structures

Antitoxin

• AlphaFold DB: A0A7V8PT23