Detailed information of TA system TA219105

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): yeeUV (cbtA-cbeA)/CbtA-CbeA
• Location: 2908758..2909569
• Replicon: chromosome
• Accession: NZ_CP084656
• Organism: Pectobacterium versatile strain SR1

Toxin (Protein)

• Gene name: yeeV
• Uniprot ID: -
• Locus tag: LGL96_RS12935
• Protein ID: WP_225586340.1
• Coordinates: 2909189..2909569 (+)
• Length: 127 a.a.

Antitoxin (Protein)

• Gene name: yeeU
• Uniprot ID: -
• Locus tag: LGL96_RS12930
• Protein ID: WP_225586339.1
• Coordinates: 2908758..2909126 (+)
• Length: 123 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LGL96_RS12885 (LGL96_12885)	2904146..2904967	+	822	WP_225586331.1	DUF932 domain-containing protein	-
LGL96_RS12890 (LGL96_12890)	2905186..2905887	+	702	WP_225586332.1	WYL domain-containing protein	-
LGL96_RS12895 (LGL96_12895)	2905928..2906167	+	240	WP_225586333.1	hypothetical protein	-
LGL96_RS12900 (LGL96_12900)	2906164..2906604	+	441	WP_225586334.1	hypothetical protein	-
LGL96_RS12905 (LGL96_12905)	2906628..2907095	+	468	WP_225586335.1	hypothetical protein	-
LGL96_RS12910 (LGL96_12910)	2907171..2907410	+	240	WP_225586336.1	DUF905 domain-containing protein	-
LGL96_RS12915 (LGL96_12915)	2907510..2907965	+	456	WP_225586337.1	antirestriction protein	-
LGL96_RS12920 (LGL96_12920)	2907981..2908505	+	525	WP_225586375.1	DNA repair protein RadC	-
LGL96_RS12925 (LGL96_12925)	2908515..2908736	+	222	WP_225586338.1	DUF987 domain-containing protein	-
LGL96_RS12930 (LGL96_12930)	2908758..2909126	+	369	WP_225586339.1	type IV toxin-antitoxin system YeeU family antitoxin	Antitoxin
LGL96_RS12935 (LGL96_12935)	2909189..2909569	+	381	WP_225586340.1	TA system toxin CbtA family protein	Toxin
LGL96_RS12940 (LGL96_12940)	2909566..2909898	+	333	WP_225586341.1	DUF5983 family protein	-
LGL96_RS12945 (LGL96_12945)	2910353..2910781	+	429	WP_103861558.1	GNAT family N-acetyltransferase	-
LGL96_RS12950 (LGL96_12950)	2910872..2911993	+	1122	WP_225586342.1	cupin domain-containing protein	-
LGL96_RS12955 (LGL96_12955)	2912292..2913428	+	1137	WP_029367920.1	lipase family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• CbtA toxin of type IV toxin-antitoxin system (1-112)

Antitoxin

• Antitoxin CbeA (19-117)

Sequences

Toxin

Protein

• Length: 127 a.a.
• Molecular weight: 14010.05 Da
• Isoelectric Point: 6.6949

>T219105 WP_225586340.1 NZ_CP084656:2909189-2909569 [Pectobacterium versatile]
MQTLPVSPERAARACPSPVEVWQMLLTHLLSQHYGLALNDTPFSDDNIIQEHIDAGISLCDAVNFIVEKYELVRTDRPGF
SVTEQSALITRIDILRARKACGLMTRNGYKAVTNITCGNKPQEPGR

Nucleotide

• Length: 381 bp

>T219105 NZ_CP116181:c3571457-3571155 [Escherichia coli]
ATGGCTCAAAAGAAAAATATAAGGAGTTTTCGTGATGCCTGGTTGGCTGATTTTTTTGTCCATTCAACGCCACATCGAAA
GATCCCTGCTGAAATCCATACCACGTTATCACGAAAGTTGGACATCATTAATGCTGCCACTTCTCATCGGGATTTACGCT
CCCCTCCGGGGAACCGATACGAAGAGTTATCCGGGAAATTACAGGAATACTCCTCCATTAGAGTGAATAAACAGTACCGA
CTGATTTTTAAATGGGTTAATGGCAAGGCCGAAGAATTGTTTTTAGACCCACACAACTACTAA

Antitoxin

Protein

• Length: 123 a.a.
• Molecular weight: 13486.36 Da
• Isoelectric Point: 7.3727

>AT219105 WP_225586339.1 NZ_CP084656:2908758-2909126 [Pectobacterium versatile]
MSQTTPATPAVNHDVTEPRWGLKRDITPCFGSRLVQEGNRLHYLADRASITGIFSNEDLRHLDQAFPLLLKQLELMLSSG
VLNPRHPHCVTLHAKGLTCDADTRGSCGYLYISIYPTPTANA

Nucleotide

• Length: 369 bp

>AT219105 NZ_CP116181:c3571119-3570778 [Escherichia coli]
ATGAAACAGGCAACAAGAAAACCGACGACACCCGGAGATATTCTTCTCTATGAATATCTGGAACCGCTCGATTTGAAAAT
CAATGAGTTAGCAGAGTTGCTGCATGTTCATCGTAATAGCGTCAGTGCACTGATCAATAACAATCGTAAACTCACCACTG
AGATGGCATTCCGTCTGGCGAAAGTTTTTGATACCACAGTCGATTTTTGGCTAAACCTCCAGGCGGCAGTTGATCTTTGG
GAAGTTGAAAACAACATGCGTACCCAGGAAGAATTGGGACGGATTGAAACAGTGGCTGAATATTTGGCACGCCGTGAAGA
GCGTGCAAAAAAGGTCGCGTAG