Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 2886596..2887121 Replicon chromosome
Accession NZ_CP084656
Organism Pectobacterium versatile strain SR1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LGL96_RS12815 Protein ID WP_039534786.1
Coordinates 2886837..2887121 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID C6D956
Locus tag LGL96_RS12810 Protein ID WP_005973616.1
Coordinates 2886596..2886847 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LGL96_RS12765 (LGL96_12765) 2881604..2881828 + 225 WP_225586698.1 hypothetical protein -
LGL96_RS22585 2881948..2882151 + 204 Protein_2477 ash family protein -
LGL96_RS12775 (LGL96_12775) 2882187..2882384 + 198 WP_211005800.1 host cell division inhibitor Icd-like protein -
LGL96_RS12780 (LGL96_12780) 2882377..2882571 + 195 WP_005973630.1 hypothetical protein -
LGL96_RS12785 (LGL96_12785) 2882568..2882834 + 267 WP_116226700.1 hypothetical protein -
LGL96_RS12790 (LGL96_12790) 2882831..2883172 + 342 WP_225586699.1 DUF5375 family protein -
LGL96_RS12795 (LGL96_12795) 2883183..2885510 + 2328 WP_211005796.1 phage/plasmid primase, P4 family -
LGL96_RS12800 (LGL96_12800) 2885564..2886043 - 480 WP_039481845.1 GNAT family N-acetyltransferase -
LGL96_RS12805 (LGL96_12805) 2886034..2886306 - 273 WP_039481848.1 DUF1778 domain-containing protein -
LGL96_RS12810 (LGL96_12810) 2886596..2886847 + 252 WP_005973616.1 prevent-host-death protein Antitoxin
LGL96_RS12815 (LGL96_12815) 2886837..2887121 + 285 WP_039534786.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LGL96_RS12820 (LGL96_12820) 2887714..2889006 + 1293 WP_225586700.1 integrase arm-type DNA-binding domain-containing protein -
LGL96_RS12825 (LGL96_12825) 2889405..2891042 - 1638 WP_225586701.1 DNA cytosine methyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2875351..2907965 32614


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10980.93 Da        Isoelectric Point: 10.1716

>T219104 WP_039534786.1 NZ_CP084656:2886837-2887121 [Pectobacterium versatile]
MSYKLEFEEHALKEFKKLGAPVREQFTKKLKEVLQNPHVPANRLHGMADCYKIKLRSAGYRLVYQVLEHEIVVLVLAVGK
RERSEVYKAAKDRL

Download         Length: 285 bp

>T219104 NZ_CP116181:2668891-2668998 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACAACCTGGCGGCACCGATCCTGGCGGGGATTATTACCGCAGTGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9079.35 Da        Isoelectric Point: 5.0807

>AT219104 WP_005973616.1 NZ_CP084656:2886596-2886847 [Pectobacterium versatile]
MSVQPILANAAVSISDFKKSPNAALKEANGEPVAVLTNGRISGYYVSPETWEALADYQEDIELAKIARSRMKGKRVKVDL
DEL

Download         Length: 252 bp

>AT219104 NZ_CP116181:c2668834-2668779 [Escherichia coli]
CAAGATTAGCCCCCGTTCTGTTGTCAGGTTGTACCTCTCAACGTGCGGGGGTTTTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0G4JQP6

References