Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/COG5606-COG4679
Location 917428..918091 Replicon chromosome
Accession NZ_CP084656
Organism Pectobacterium versatile strain SR1

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag LGL96_RS03930 Protein ID WP_103940843.1
Coordinates 917428..917772 (+) Length 115 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag LGL96_RS03935 Protein ID WP_103940841.1
Coordinates 917774..918091 (+) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LGL96_RS03905 (LGL96_03905) 912984..914114 + 1131 WP_103940853.1 linear amide C-N hydrolase -
LGL96_RS03910 (LGL96_03910) 914224..914532 - 309 WP_103940851.1 YciI family protein -
LGL96_RS03915 (LGL96_03915) 914572..915192 - 621 WP_103940849.1 FMN-dependent NADH-azoreductase -
LGL96_RS03920 (LGL96_03920) 915227..916000 - 774 WP_103940847.1 alpha/beta hydrolase -
LGL96_RS03925 (LGL96_03925) 916168..917196 + 1029 WP_103940845.1 helix-turn-helix domain-containing protein -
LGL96_RS03930 (LGL96_03930) 917428..917772 + 345 WP_103940843.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LGL96_RS03935 (LGL96_03935) 917774..918091 + 318 WP_103940841.1 helix-turn-helix transcriptional regulator Antitoxin
LGL96_RS03940 (LGL96_03940) 918305..918520 - 216 WP_010279992.1 helix-turn-helix transcriptional regulator -
LGL96_RS03945 (LGL96_03945) 918760..919251 - 492 WP_103940839.1 GNAT family N-acetyltransferase -
LGL96_RS03950 (LGL96_03950) 919255..919524 - 270 WP_039532549.1 DUF1778 domain-containing protein -
LGL96_RS03955 (LGL96_03955) 919847..920185 + 339 WP_010279998.1 putative addiction module antidote protein -
LGL96_RS03960 (LGL96_03960) 920277..920879 - 603 WP_103941405.1 TetR/AcrR family transcriptional regulator -
LGL96_RS03965 (LGL96_03965) 921054..921920 + 867 WP_223878567.1 NADP-dependent oxidoreductase -
LGL96_RS03970 (LGL96_03970) 921950..922828 + 879 WP_103940835.1 aldo/keto reductase family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-105)

Antitoxin

Cro/C1-type helix-turn-helix domain

(34-86)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 12418.13 Da        Isoelectric Point: 9.7825

>T219093 WP_103940843.1 NZ_CP084656:917428-917772 [Pectobacterium versatile]
MKSLYWVGSSKKDLQSLPADVQDVFGYALHLAQTGGKHTQAKPLKGFGGAGVLEVVEDYIGDTYRAVYTVKFGEAVYVLH
AFQKKSSSGIATQKPDMNTIRERLKTAENHAKGA

Download         Length: 345 bp

>T219093 NZ_CP116181:190198-190305 [Escherichia coli]
ATGACGCTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11372.41 Da        Isoelectric Point: 10.8066

>AT219093 WP_103940841.1 NZ_CP084656:917774-918091 [Pectobacterium versatile]
MSQDIEVSSGNVYADLGNLHAEGMLVKAQLATLISSIIKSRRLTQAEAAKLLGIPQPKLSNLLRGQFRGISETKMLECLT
KLGRDIQIVVGKPRRTPGSVKVVFA

Download         Length: 318 bp

>AT219093 NZ_CP116181:c190141-190084 [Escherichia coli]
TCAAGATTAGCCCCCGTGATGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References