Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ykfI-yfjZ/CbtA-CbeA
Location 811994..812718 Replicon chromosome
Accession NZ_CP084656
Organism Pectobacterium versatile strain SR1

Toxin (Protein)


Gene name ykfI Uniprot ID -
Locus tag LGL96_RS03460 Protein ID WP_116156147.1
Coordinates 812398..812718 (+) Length 107 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag LGL96_RS03455 Protein ID WP_130622702.1
Coordinates 811994..812329 (+) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LGL96_RS03425 (LGL96_03425) 807942..808817 + 876 WP_130622706.1 GTPase family protein -
LGL96_RS03430 (LGL96_03430) 809187..809885 + 699 WP_107333349.1 DeoR family transcriptional regulator -
LGL96_RS03435 (LGL96_03435) 810065..810637 + 573 WP_225591977.1 hypothetical protein -
LGL96_RS03440 (LGL96_03440) 810673..811146 + 474 WP_130622704.1 hypothetical protein -
LGL96_RS03445 (LGL96_03445) 811163..811396 + 234 WP_040034648.1 membrane protein -
LGL96_RS03450 (LGL96_03450) 811481..811954 + 474 WP_130622703.1 DNA repair protein RadC -
LGL96_RS03455 (LGL96_03455) 811994..812329 + 336 WP_130622702.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
LGL96_RS03460 (LGL96_03460) 812398..812718 + 321 WP_116156147.1 TA system toxin CbtA family protein Toxin
LGL96_RS03465 (LGL96_03465) 812836..813669 + 834 WP_116156146.1 DUF4942 domain-containing protein -
LGL96_RS03470 (LGL96_03470) 813763..813993 + 231 WP_039360473.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
LGL96_RS03475 (LGL96_03475) 813993..814397 + 405 WP_116156145.1 tRNA(fMet)-specific endonuclease VapC -
LGL96_RS03480 (LGL96_03480) 814736..814882 + 147 Protein_683 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
LGL96_RS03485 (LGL96_03485) 814973..816406 - 1434 WP_225586101.1 FAD-binding protein -
LGL96_RS03490 (LGL96_03490) 816403..817281 - 879 WP_225586102.1 TauD/TfdA family dioxygenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-105)

Antitoxin

Antitoxin CbeA

(7-106)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12028.91 Da        Isoelectric Point: 5.0492

>T219091 WP_116156147.1 NZ_CP084656:812398-812718 [Pectobacterium versatile]
MQTSPAIPPREDIPCPLPVAVWQQLLTYLLEKHYGLTLNDTPFCEENVIQAHIDAGVTLVNAVNFLVEKYELVRIDRNGF
NWQEQSPFLTAVDILRARRAIGLLKA

Download         Length: 321 bp

>T219091 NZ_CP116177:93188-93337 [Escherichia coli]
ATGACGAAATATGCCCTTATCGGGTTGCTCGCCGTGTGTGCCACGGTATTGTGTTTTTCACTGATATTCAGGGAACGGTT
ATGTGAACTGAATATTCACAGGGGAAATACAGTGGTGCAGGTAACTCTGGCCTACGAAGCACGGAAGTAA

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12352.01 Da        Isoelectric Point: 5.6948

>AT219091 WP_130622702.1 NZ_CP084656:811994-812329 [Pectobacterium versatile]
MPSSDTPEWGLKCAITPRFGARLVQEGNRLHYLADRASVVGTFSKTEAQSLERCFPELIKLLEQKLRTGELNPRQPGCIT
QHCNDWTCEADTLGSFGYVYIVIYPSSAAAE

Download         Length: 336 bp

>AT219091 NZ_CP116177:c93143-93084 [Escherichia coli]
TAAGTACTTCATGCAGACCTCACGAGTTAATGGATTAACGAGTGGGGTCTTCGCATTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References