Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 2581714..2582264 Replicon chromosome
Accession NZ_CP084655
Organism Pectobacterium brasiliense strain SR10

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag LGL97_RS11545 Protein ID WP_225583583.1
Coordinates 2581714..2582022 (-) Length 103 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag LGL97_RS11550 Protein ID WP_225583581.1
Coordinates 2582025..2582264 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LGL97_RS11525 (LGL97_11525) 2577467..2578372 - 906 WP_225583588.1 LysR family transcriptional regulator -
LGL97_RS11530 (LGL97_11530) 2578657..2579586 + 930 WP_052903037.1 aromatic alcohol reductase -
LGL97_RS11535 (LGL97_11535) 2579637..2581295 - 1659 WP_225583585.1 HTH-type transcriptional regulator SgrR -
LGL97_RS11540 (LGL97_11540) 2581386..2581550 + 165 WP_010681730.1 glucose uptake inhibitor SgrT -
LGL97_RS11545 (LGL97_11545) 2581714..2582022 - 309 WP_225583583.1 CcdB family protein Toxin
LGL97_RS11550 (LGL97_11550) 2582025..2582264 - 240 WP_225583581.1 type II toxin-antitoxin system CcdA family antitoxin Antitoxin
LGL97_RS11555 (LGL97_11555) 2582965..2584584 + 1620 WP_225583579.1 methyl-accepting chemotaxis protein -
LGL97_RS11560 (LGL97_11560) 2584795..2585631 + 837 WP_052903031.1 AraC family transcriptional regulator -
LGL97_RS11565 (LGL97_11565) 2585737..2586471 + 735 WP_225583577.1 AzlC family ABC transporter permease -
LGL97_RS11570 (LGL97_11570) 2586468..2586779 + 312 WP_039317163.1 AzlD domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-101)

Antitoxin

Post-segregation antitoxin CcdA

(9-79)


Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 11804.57 Da        Isoelectric Point: 8.4503

>T219088 WP_225583583.1 NZ_CP084655:c2582022-2581714 [Pectobacterium brasiliense]
MQYKVYRNNGNSNSYPYLLNVQSDIIGELHTRQVIPLFPLHNIARPPARRLTPIVTVEGNDYLIMTHEMASVRRSQLGHE
VMDAQMYRKTIKDAVDFLLDGF

Download         Length: 309 bp

>T219088 NZ_CP116176:4074747-4075211 [Escherichia coli]
ATGGATTTTCCACAAAGGGTTAATGGTTGGGCGCTATATGCTCATCCCTGTTTTCAGGAAACCTACGACGCTTTAGTTGC
CGAAGTCGAGACATTAAAGGGAAAAGATCCTGAAAATTATCAGAGAAAAGCCGCCACAAAGTTATTGGCGGTAGTCCATA
AAGTGATTGAGGAGCATATCACGGTCAATCCATCATCACCGGCATTCCGTCATGGCAAGTCGTTAGGCTCTGGGAAAAAT
AAAGACTGGTCACGGGTAAAATTTGGTGCTGGTCGTTATCGTCTCTTCTTTCGTTATAGTGAAAAAGAGAAAGTCATCAT
TCTGGGATGGATGAACGATGAAAACACTCTGCGCACCTACGGTAAAAAAACAGATGCCTATACCGTATTCAGCAAAATGT
TAAAAAGAGGACATCCTCCTGCCGACTGGGAAAGCCTCACCCAAGAGACAGAAGAAAACCATTGA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9088.42 Da        Isoelectric Point: 10.0137

>AT219088 WP_225583581.1 NZ_CP084655:c2582264-2582025 [Pectobacterium brasiliense]
MPVTSVRHKKTVSVTLEPMLLQQAREAGINLSAILTEALKREFRLSEGEKWKQQNQKALQELNRITDKHGLLSDDDRTF

Download         Length: 240 bp

>AT219088 NZ_CP116176:4074412-4074747 [Escherichia coli]
ATGCCCGCTAATGCTCGCTCTCACGCTGTACTGACCACTGAATCAAAGGTCACGATACGCGGACAAACAACTATCCCCGC
GCCAGTGCGTGAGGCCTTAAAACTGAAGCCAGGCCAGGACAGCATTCATTACGAAATTCTGCCTGGTGGGCAAGTCTTTA
TGTGCCGACTGGGAGATGAACAGGAGGATCATACTATGAATGCATTTTTGCGTTTTCTGGATGCAGATATCCAGAACAAC
CCGCAAAAAACTCGTCCATTCAACATTCAACAAGGAAAGAAACTTGTCGCTGGCATGGACGTCAACATTGATGATGAGAT
TGGCGACGACGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References