Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 1075331..1075991 Replicon chromosome
Accession NZ_CP084655
Organism Pectobacterium brasiliense strain SR10

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag LGL97_RS04750 Protein ID WP_048256537.1
Coordinates 1075331..1075705 (-) Length 125 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A1D7Z1Z6
Locus tag LGL97_RS04755 Protein ID WP_005971623.1
Coordinates 1075725..1075991 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LGL97_RS04725 (LGL97_04725) 1071129..1072457 + 1329 WP_010279860.1 MFS transporter -
LGL97_RS04730 (LGL97_04730) 1072662..1073048 + 387 WP_010279856.1 thioesterase family protein -
LGL97_RS04735 (LGL97_04735) 1073391..1073909 + 519 WP_119870590.1 flavodoxin FldB -
LGL97_RS04740 (LGL97_04740) 1073938..1074261 + 324 WP_039312863.1 hypothetical protein -
LGL97_RS04745 (LGL97_04745) 1074327..1075262 - 936 WP_039496936.1 23S rRNA (adenine(1618)-N(6))-methyltransferase RlmF -
LGL97_RS04750 (LGL97_04750) 1075331..1075705 - 375 WP_048256537.1 protein YgfX Toxin
LGL97_RS04755 (LGL97_04755) 1075725..1075991 - 267 WP_005971623.1 FAD assembly factor SdhE Antitoxin
LGL97_RS04760 (LGL97_04760) 1076227..1077228 + 1002 WP_010279836.1 tRNA-modifying protein YgfZ -
LGL97_RS04765 (LGL97_04765) 1077283..1077930 - 648 WP_010279833.1 hemolysin III family protein -
LGL97_RS04770 (LGL97_04770) 1078354..1078962 + 609 WP_010279828.1 HD domain-containing protein -
LGL97_RS04775 (LGL97_04775) 1079017..1080021 + 1005 WP_010279825.1 LacI family DNA-binding transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-119)

Antitoxin

Flavinator of succinate dehydrogenase

(8-79)


Sequences

Toxin        


Download         Length: 125 a.a.        Molecular weight: 14668.36 Da        Isoelectric Point: 10.5560

>T219078 WP_048256537.1 NZ_CP084655:c1075705-1075331 [Pectobacterium brasiliense]
MQLLSLVVHGLLVLLILLAPWPDGYAWLWLCLVTMVMFGFIRSQRNIKSRQGEIVLLSETTLNWRQQEWQIVKRPWLLKN
GILLSLQAVNGKDKQQLWLASDSMGDDEWRHLRQILLQQKHWAR

Download         Length: 375 bp

>T219078 NZ_CP116176:c1988442-1988335 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10507.94 Da        Isoelectric Point: 5.1392

>AT219078 WP_005971623.1 NZ_CP084655:c1075991-1075725 [Pectobacterium brasiliense]
MEIDNKSRIHWACRRGMRELDIAIMPFFEHDYDTLNDTDKRTFVRLLQSDDPDLFNWLMNHGEPEDGELKRMISLIQTRN
KDRGPVAM

Download         Length: 267 bp

>AT219078 NZ_CP116176:1988490-1988556 [Escherichia coli]
GTTCTGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTAAACCTCTCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A1D7Z1Z6

References