Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 4925814..4926349 Replicon chromosome
Accession NZ_CP084654
Organism Pectobacterium versatile strain SR12

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LGL95_RS21995 Protein ID WP_103162646.1
Coordinates 4926062..4926349 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID Q6DB37
Locus tag LGL95_RS21990 Protein ID WP_010281712.1
Coordinates 4925814..4926065 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LGL95_RS21970 (LGL95_21970) 4922288..4922725 + 438 WP_010296551.1 RICIN domain-containing protein -
LGL95_RS21975 (LGL95_21975) 4922970..4923593 - 624 WP_039474438.1 LysE family translocator -
LGL95_RS21980 (LGL95_21980) 4923861..4924616 + 756 WP_226306040.1 thiol:disulfide interchange protein DsbG -
LGL95_RS21985 (LGL95_21985) 4924651..4925556 - 906 WP_125232109.1 siderophore-interacting protein -
LGL95_RS21990 (LGL95_21990) 4925814..4926065 + 252 WP_010281712.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
LGL95_RS21995 (LGL95_21995) 4926062..4926349 + 288 WP_103162646.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LGL95_RS22000 (LGL95_22000) 4926541..4926966 - 426 WP_249642145.1 AbiH family protein -
LGL95_RS22005 (LGL95_22005) 4927045..4928256 + 1212 Protein_4295 IS3 family transposase -
LGL95_RS22010 (LGL95_22010) 4928175..4928759 - 585 WP_226306041.1 AbiH family protein -
LGL95_RS22015 (LGL95_22015) 4928761..4929861 - 1101 WP_226306042.1 PIN domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-84)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11083.21 Da        Isoelectric Point: 10.4703

>T219073 WP_103162646.1 NZ_CP084654:4926062-4926349 [Pectobacterium versatile]
MSYRVKFREDALKEWLKLDKAIQQQFAKKLKKCCENPHIPAAKLRGMKDCYKIKLRASGFRLVYEVIDDVLVIAVVAVGK
RERSGVYHLASERMR

Download         Length: 288 bp

>T219073 NZ_CP116171:2544-2822 [Escherichia coli]
ATGGAGATATTCTGGACCATGCTGGCCAGCCAGGACAGGAAGCGCATTCGTGAGTACATTGCGGAGCAGAACCTGATGGC
CGCCATTGAACTGGACGAACGGATTGGTTATTCAGCCAGCAGCCTGGCCGGGCAGCCGTATAAAGGTCGCAACGGTCGTG
TGGAAGGAACCCGGGAACTGGTTATTCACCCCCATTTTGTTCTGGTTTATGAGGTCGACAGCCAGTGGGGAAAAGTGTAT
GTCCTGCGCGTGTTGCATACCGCACAGAAGTGGCCATAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9117.47 Da        Isoelectric Point: 4.0637

>AT219073 WP_010281712.1 NZ_CP084654:4925814-4926065 [Pectobacterium versatile]
MPNIILSDTSASVSELKKNPMATVNAGDGLPVAILNRNQPAFYCIPADLYEKMLDALDDQELVKLIGERKNQPLVDVDLD
SFL

Download         Length: 252 bp

>AT219073 NZ_CP116171:2275-2544 [Escherichia coli]
ATGGCACAGGTTAATATGAGTTTAAGAATCGACGCTGAACTGAAGGATGCTTTTATGGCCGCTGCAAAAAGCATGGACCG
TAATGGCTCTCAGTTAATTCGGGATTTTATGCGCCAGACCGTTGAACGGCAGCATAATACCTGGTTCCGTGACCAGGTTG
CGGCAGGACGTCAGCAACTCGAGCGCGGCGATGTGCTTCCCCATGACATGGTCGAATCTTCTGCCGCTGCATGGCGGGAT
GAAATGAGCAGGAAGGTTTCCGATAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0M2EZP0

References