Detailed information of TA system TA219072

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): sdenTA/AbiEii(toxin)
• Location: 4856523..4857963
• Replicon: chromosome
• Accession: NZ_CP084654
• Organism: Pectobacterium versatile strain SR12

Toxin (Protein)

• Gene name: sdenT
• Uniprot ID: -
• Locus tag: LGL95_RS21680
• Protein ID: WP_226306030.1
• Coordinates: 4856523..4857410 (-)
• Length: 296 a.a.

Antitoxin (Protein)

• Gene name: sdenA
• Uniprot ID: -
• Locus tag: LGL95_RS21685
• Protein ID: WP_095993166.1
• Coordinates: 4857439..4857963 (-)
• Length: 175 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LGL95_RS21660 (LGL95_21660)	4852514..4853335	+	822	WP_014913737.1	M55 family metallopeptidase	-
LGL95_RS21665 (LGL95_21665)	4853395..4854342	+	948	WP_103862782.1	isoaspartyl peptidase/L-asparaginase	-
LGL95_RS21670 (LGL95_21670)	4854547..4855455	+	909	WP_039542502.1	LysR family transcriptional regulator	-
LGL95_RS21675 (LGL95_21675)	4855554..4856417	+	864	WP_095993164.1	YicC/YloC family endoribonuclease	-
LGL95_RS21680 (LGL95_21680)	4856523..4857410	-	888	WP_226306030.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
LGL95_RS21685 (LGL95_21685)	4857439..4857963	-	525	WP_095993166.1	hypothetical protein	Antitoxin
LGL95_RS21690 (LGL95_21690)	4859028..4859330	+	303	WP_226306031.1	hypothetical protein	-
LGL95_RS21695 (LGL95_21695)	4859411..4860661	-	1251	WP_105880051.1	type II toxin-antitoxin system HipA family toxin	-
LGL95_RS21700 (LGL95_21700)	4860658..4860963	-	306	WP_105880113.1	transcriptional regulator	-
LGL95_RS21705 (LGL95_21705)	4861265..4861492	+	228	WP_105880052.1	hypothetical protein	-
LGL95_RS21710 (LGL95_21710)	4861584..4862141	+	558	WP_105880054.1	hypothetical protein	-
LGL95_RS21715 (LGL95_21715)	4862184..4862729	-	546	WP_080728696.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (36-265)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 296 a.a.
• Molecular weight: 33957.88 Da
• Isoelectric Point: 5.9873

>T219072 WP_226306030.1 NZ_CP084654:c4857410-4856523 [Pectobacterium versatile]
MLKQQIRQIVQSNPDYAAVTPVIEKEILHHDIMDVLIKQGVMQRLTFIGGTSLRMCYNSSRLSEDLDFNGGHDFKPSAFE
GLESEIQTYIQNKYETEVWVNKPSGEQQGDTVSWKISIVKDANRPDLPRQKMHIDVCAIPSFDIEKRPLINHYDIVVPTE
GILVPVQSLQETLADKLIALAYRARRIKPRDIWDIVWIKQRGIDLSKTLVEKKLTARQKQTEDFRQALSIQLAKLMSEDE
VRDDFNMEMSRFISKQIKERTLDNPAYWAYVQGEVHAIASELLNDGTPKNPFDMG

Nucleotide

• Length: 888 bp

>T219072 NZ_CP116170:c88644-88369 [Escherichia coli]
ATGGAACTGAAGTGGACCAGTAAGGCGCTTTCTGATTTGGCGCGGTTATATGATTTTCTGGCGCTGGCCAGTAAACCAGC
TGCAGCCAGAACGGTGCAGTCCCTGACACAGGCACCGGTCATTCTGTTAACTCATCCACGTATGGGAGAACAGTTGTTTC
AGTTTGAACCCAGGGAGGTCAGACGGATTTATGCTGGCGAGTACGAAATCCGTTACGAACTTACTGGCCAGACTATTTAT
GTATTGCGCCTGTGGCACACACGAGAAAACAGGTAG

Antitoxin

Protein

• Length: 175 a.a.
• Molecular weight: 19339.48 Da
• Isoelectric Point: 9.0504

>AT219072 WP_095993166.1 NZ_CP084654:c4857963-4857439 [Pectobacterium versatile]
MAKSDELLNALAKAVNAGGGIHSVTELAFMQGVPCDSAFRKFLADCVKKGLLRRVVKGFYESVITPPEPETAIYKIIKKL
RSGVLSYISLESQLSHTGDISQVVMGRVTVVTKGRSGCFDTPYGVIEFTHTKKPVEQIAPNLYYDPDIKMYRAYKEQAIA
DLKHCQRNLHMLES

Nucleotide

• Length: 525 bp

>AT219072 NZ_CP116170:c88928-88644 [Escherichia coli]
ATGCAAATGAAAAACAATACCGCACAAGTAACAAAAGTAATTACTGCGCATGTGCCATTACCTATGGCTGATAAAGTCGA
CCAGATGGCCGCCAGACTGGAACGGTCCCGGGGCTGGATTATCAAACAGGCGCTTTCTGCATGGCTTGCCCAGGAGGAGG
AGCGTAATCGCCTGACGCTGGAAGCCCTGGACGATGTGACATCCGGACAGGTTATCGACCATCAGGCTGTACAGGCCTGG
GCGGACAGCCTCGGTACTGACAATCCGTTACCGGTGCCTCGCTGA