Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ykfI-yfjZ/CbtA-CbeA
Location 4512045..4512770 Replicon chromosome
Accession NZ_CP084654
Organism Pectobacterium versatile strain SR12

Toxin (Protein)


Gene name ykfI Uniprot ID -
Locus tag LGL95_RS20080 Protein ID WP_226305969.1
Coordinates 4512045..4512365 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag LGL95_RS20085 Protein ID WP_226305970.1
Coordinates 4512435..4512770 (-) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LGL95_RS20060 (LGL95_20060) 4507876..4508997 - 1122 WP_226305966.1 cupin domain-containing protein -
LGL95_RS20065 (LGL95_20065) 4509088..4509516 - 429 WP_103942086.1 GNAT family N-acetyltransferase -
LGL95_RS20070 (LGL95_20070) 4510013..4511020 - 1008 WP_226305967.1 restriction endonuclease -
LGL95_RS20075 (LGL95_20075) 4511097..4511927 - 831 WP_226305968.1 DUF4942 domain-containing protein -
LGL95_RS20080 (LGL95_20080) 4512045..4512365 - 321 WP_226305969.1 TA system toxin CbtA family protein Toxin
LGL95_RS20085 (LGL95_20085) 4512435..4512770 - 336 WP_226305970.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
LGL95_RS20090 (LGL95_20090) 4512810..4513283 - 474 WP_226305971.1 DNA repair protein RadC -
LGL95_RS20095 (LGL95_20095) 4513488..4514093 - 606 WP_226305972.1 hypothetical protein -
LGL95_RS20100 (LGL95_20100) 4514122..4514676 - 555 WP_226305973.1 hypothetical protein -
LGL95_RS20105 (LGL95_20105) 4514975..4515850 - 876 WP_226305974.1 50S ribosome-binding GTPase -
LGL95_RS20110 (LGL95_20110) 4515933..4516781 - 849 WP_226305975.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-105)

Antitoxin

Antitoxin CbeA

(7-106)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12101.83 Da        Isoelectric Point: 5.0634

>T219068 WP_226305969.1 NZ_CP084654:c4512365-4512045 [Pectobacterium versatile]
MQPSPTIPSREDNPCASPIAVWQQLLTYLLEKHYGLTLNYTPFCEENVIQEHIDAGITLVNAVNFLVEKYELVRIDRNGF
NWQEQSPFLTAVDVLRARRATGLLKA

Download         Length: 321 bp

>T219068 NZ_CP116169:c4186298-4185921 [Escherichia coli]
ATGAATACATTACCCGACACTCACGTACGGGAGGCATCGGGCTGCCCGTCTCCCGTCACCATCTGGCAGACACTGCTCAC
CCGACTGCTGGACCAGCACTATGGCCTCACGCTGAATGACACACCGTTCGCTGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGGATTTCACTGTGTGACGCGGTGAACTTTCTCGTTGAAAAATACGCGCTGGTACGTACCGACCAGCCAGGATTC
AGCGCAGGAGCCCCGTCGCAGTTAATCAACAGCATCGATATTCTCCGGGCCCGCAGGGCGACCGGCCTGATGACCCGCAG
CCACTACAGAACGGTAAATGACATTACCCAGGGTAAACGCACGGAGGCAAAACGATGA

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12260.99 Da        Isoelectric Point: 7.0582

>AT219068 WP_226305970.1 NZ_CP084654:c4512770-4512435 [Pectobacterium versatile]
MPSSDTPEWGLKCAITPRFGARLVQEGNRLHYLADRASVVGTFSKTGAQSLERCFPELIKQLEQKLRTGELNPRQQGCVT
LHCNEWACEADTLGSVGYVYIVIYPTSAATL

Download         Length: 336 bp

>AT219068 NZ_CP116169:c4186722-4186345 [Escherichia coli]
GTGTCAGACACACTCCCCGGGACAACGCTTCCCGACGACAATCACGACCGCCCCTGGTGGGGGCTGCCCTGCACCGTGAC
GCCCTGTTTCGGGGCCCGACTGGTACAGGAGGGTAACCGCCTGCATTACCTTGCAGACCGCGCCGGTATCAGAGGCAGGT
TCAGCGACGCAGATGCGTACCACCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGGAACTCATGCTCACCGGCGGT
GAACTGAATCCCCGCCATCAGCATACCGTCACACTGTATGCGAAAGGGCTGACCTGCGAAGCCGATACCCTTGGCAGTTG
TGGTTACGTTTATCTGGCTGTTTATCCGACACCGGCAGCGCCCGCAATCACCGTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References