Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | mosAT/AbiEii-AbiEi |
| Location | 4383392..4385102 | Replicon | chromosome |
| Accession | NZ_CP084654 | ||
| Organism | Pectobacterium versatile strain SR12 | ||
Toxin (Protein)
| Gene name | mosT | Uniprot ID | - |
| Locus tag | LGL95_RS19565 | Protein ID | WP_130622636.1 |
| Coordinates | 4384161..4385102 (+) | Length | 314 a.a. |
Antitoxin (Protein)
| Gene name | mosA | Uniprot ID | - |
| Locus tag | LGL95_RS19560 | Protein ID | WP_130622637.1 |
| Coordinates | 4383392..4384174 (+) | Length | 261 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LGL95_RS19525 (LGL95_19525) | 4379901..4380476 | + | 576 | WP_040030982.1 | transcriptional regulator | - |
| LGL95_RS19530 (LGL95_19530) | 4380473..4381063 | - | 591 | WP_226305942.1 | LysE family translocator | - |
| LGL95_RS19535 (LGL95_19535) | 4381099..4381944 | - | 846 | WP_010301509.1 | AraC family transcriptional regulator | - |
| LGL95_RS19545 (LGL95_19545) | 4382261..4382470 | - | 210 | WP_039496801.1 | helix-turn-helix transcriptional regulator | - |
| LGL95_RS19550 (LGL95_19550) | 4382467..4382928 | - | 462 | WP_130622638.1 | hypothetical protein | - |
| LGL95_RS19555 (LGL95_19555) | 4382892..4383065 | - | 174 | WP_072012970.1 | ash family protein | - |
| LGL95_RS19560 (LGL95_19560) | 4383392..4384174 | + | 783 | WP_130622637.1 | type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein | Antitoxin |
| LGL95_RS19565 (LGL95_19565) | 4384161..4385102 | + | 942 | WP_130622636.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | Toxin |
| LGL95_RS19570 (LGL95_19570) | 4385386..4386288 | - | 903 | WP_103164620.1 | LysR family transcriptional regulator | - |
| LGL95_RS19575 (LGL95_19575) | 4386417..4386680 | + | 264 | WP_010286385.1 | DUF2798 domain-containing protein | - |
| LGL95_RS19580 (LGL95_19580) | 4386764..4387549 | - | 786 | WP_226305943.1 | phosphonate metabolism protein PhnP | - |
| LGL95_RS19585 (LGL95_19585) | 4387588..4388157 | - | 570 | WP_211007588.1 | ribose 1,5-bisphosphokinase | - |
| LGL95_RS19590 (LGL95_19590) | 4388305..4388499 | - | 195 | Protein_3827 | alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase | - |
| LGL95_RS19595 (LGL95_19595) | 4388489..4388787 | - | 299 | Protein_3828 | ATP-binding cassette domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 314 a.a. Molecular weight: 35528.04 Da Isoelectric Point: 6.0934
>T219066 WP_130622636.1 NZ_CP084654:4384161-4385102 [Pectobacterium versatile]
MDQRDIYARQVKLLMTALPHVAKEPCFALKGGTAINLFVQDFPRLSVDIDLVYQTFIDRDTDLVAIDDALMRITESLNGR
PGITAILQENKADEKRIIVNTVDAHIKIEVSPVWRGLLLPPAELPVCEQVEMEFGFTTMNVVSLADLYGGKICAALDRQH
PRDLFDVLNMLEKPGLTRELFDGFLCYLAGHPRPIAELLAPNWDIARITTLYQQEFSGMTQQETSLESLLSVTILLPQAL
RSHFTVQDKQFLLSYKQNTPDWSLYRYPDIQHLPAIRWKQHNLSTLHTKNPAKFSAAVGKLEKVLEQRFSPVS
MDQRDIYARQVKLLMTALPHVAKEPCFALKGGTAINLFVQDFPRLSVDIDLVYQTFIDRDTDLVAIDDALMRITESLNGR
PGITAILQENKADEKRIIVNTVDAHIKIEVSPVWRGLLLPPAELPVCEQVEMEFGFTTMNVVSLADLYGGKICAALDRQH
PRDLFDVLNMLEKPGLTRELFDGFLCYLAGHPRPIAELLAPNWDIARITTLYQQEFSGMTQQETSLESLLSVTILLPQAL
RSHFTVQDKQFLLSYKQNTPDWSLYRYPDIQHLPAIRWKQHNLSTLHTKNPAKFSAAVGKLEKVLEQRFSPVS
Download Length: 942 bp
>T219066 NZ_CP116169:3676066-3676344 [Escherichia coli]
ATGATTCAAAGGGATATTGAATACTCGGGACAATTTTCAAAGGATGTAAAACTTGCACAAAAGCGTCATAAGGATATGAA
TAAATTGAAATATCTTATGACGCTTCTTATCAATAATGCTTTACCGCTTCCAGCTGTTTATAAAGACCACCCGCTGCAAG
GTTCATGGAAAGGTTATCGCGATGCTCATGTCGAACCGGACTGGATCCTGATTTACAAACTTACCGATAAACTTTTACGA
TTTGAGAGAACTGGAACTCACGCGGCGCTCTTTGGGTAA
ATGATTCAAAGGGATATTGAATACTCGGGACAATTTTCAAAGGATGTAAAACTTGCACAAAAGCGTCATAAGGATATGAA
TAAATTGAAATATCTTATGACGCTTCTTATCAATAATGCTTTACCGCTTCCAGCTGTTTATAAAGACCACCCGCTGCAAG
GTTCATGGAAAGGTTATCGCGATGCTCATGTCGAACCGGACTGGATCCTGATTTACAAACTTACCGATAAACTTTTACGA
TTTGAGAGAACTGGAACTCACGCGGCGCTCTTTGGGTAA
Antitoxin
Download Length: 261 a.a. Molecular weight: 29239.63 Da Isoelectric Point: 9.4769
>AT219066 WP_130622637.1 NZ_CP084654:4383392-4384174 [Pectobacterium versatile]
MTNYLNWLMQNTLPGQVLLQSWLTRNGIDRKLSYVYVQNGWLRRIAHGVYCRTGREPDWVDAVYCLQTQWEKPVRVAGLT
SLALQGYSHYTELGKPQVWLTLPAYIKLPGWFAAFEPSATFVVLYTSGLSVDVMPFTTELKIGDRRLTGSVPELAAYEIA
SGVPTQISFEHADALFQGLHLLSPRKLQALLSASRSIKTNRVMLYLAQRNGHPYFQYLDKSGIEIGAGKRQIVPGGWLEP
GYQITVPREFKSKGIEDGSA
MTNYLNWLMQNTLPGQVLLQSWLTRNGIDRKLSYVYVQNGWLRRIAHGVYCRTGREPDWVDAVYCLQTQWEKPVRVAGLT
SLALQGYSHYTELGKPQVWLTLPAYIKLPGWFAAFEPSATFVVLYTSGLSVDVMPFTTELKIGDRRLTGSVPELAAYEIA
SGVPTQISFEHADALFQGLHLLSPRKLQALLSASRSIKTNRVMLYLAQRNGHPYFQYLDKSGIEIGAGKRQIVPGGWLEP
GYQITVPREFKSKGIEDGSA
Download Length: 783 bp
>AT219066 NZ_CP116169:3675803-3676063 [Escherichia coli]
ATGGCTGCTAACGCATTTGTTCGCGCCCGAATCGATGAAGATCTGAAGAATCAGGCGGCGGACGTACTGGCCGGGATGGG
GCTGACCATCTCTGACCTGGTTCGCATAACCCTCACAAAGGTCGCGCGTGAAAAGGCATTGCCGTTTGATTTACGCGAGC
CTAATCAATTAACCATTCAATCAATCAAAAACAGCGAAGCTGGCGTTGATGTTCATAAGGCCAAAGACGCCGATGATTTA
TTTGATAAATTAGGAATTTAA
ATGGCTGCTAACGCATTTGTTCGCGCCCGAATCGATGAAGATCTGAAGAATCAGGCGGCGGACGTACTGGCCGGGATGGG
GCTGACCATCTCTGACCTGGTTCGCATAACCCTCACAAAGGTCGCGCGTGAAAAGGCATTGCCGTTTGATTTACGCGAGC
CTAATCAATTAACCATTCAATCAATCAAAAACAGCGAAGCTGGCGTTGATGTTCATAAGGCCAAAGACGCCGATGATTTA
TTTGATAAATTAGGAATTTAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|