Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 4133421..4133913 Replicon chromosome
Accession NZ_CP084654
Organism Pectobacterium versatile strain SR12

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LGL95_RS18415 Protein ID WP_226305901.1
Coordinates 4133662..4133913 (+) Length 84 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LGL95_RS18410 Protein ID WP_105879157.1
Coordinates 4133421..4133672 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LGL95_RS18385 (LGL95_18385) 4128434..4128601 + 168 Protein_3595 DNA-binding protein -
LGL95_RS18390 (LGL95_18390) 4128696..4128913 + 218 Protein_3596 integrase -
LGL95_RS18395 (LGL95_18395) 4128967..4131486 + 2520 WP_130623843.1 SIR2 family protein -
LGL95_RS18400 (LGL95_18400) 4132492..4132821 - 330 WP_223193302.1 DUF1493 family protein -
LGL95_RS18405 (LGL95_18405) 4132821..4133291 - 471 WP_103861352.1 hypothetical protein -
LGL95_RS18410 (LGL95_18410) 4133421..4133672 + 252 WP_105879157.1 prevent-host-death protein Antitoxin
LGL95_RS18415 (LGL95_18415) 4133662..4133913 + 252 WP_226305901.1 hypothetical protein Toxin
LGL95_RS18420 (LGL95_18420) 4134085..4134336 + 252 WP_005973616.1 prevent-host-death protein -
LGL95_RS18425 (LGL95_18425) 4134326..4134610 + 285 WP_039539560.1 type II toxin-antitoxin system RelE/ParE family toxin -
LGL95_RS18430 (LGL95_18430) 4134876..4135052 + 177 WP_158256803.1 hypothetical protein -
LGL95_RS18435 (LGL95_18435) 4135270..4135848 + 579 WP_130621939.1 hypothetical protein -
LGL95_RS18440 (LGL95_18440) 4136216..4136998 + 783 WP_226305902.1 transporter substrate-binding domain-containing protein -
LGL95_RS18445 (LGL95_18445) 4137254..4137880 + 627 WP_010295795.1 LysE family transporter -
LGL95_RS18450 (LGL95_18450) 4137926..4138408 - 483 WP_029367525.1 GNAT family N-acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 4127403..4135848 8445


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 9997.60 Da        Isoelectric Point: 10.0265

>T219063 WP_226305901.1 NZ_CP084654:4133662-4133913 [Pectobacterium versatile]
MSYKLEFEEHALKEFKKLRAPMWEQFTKKLKDILQNPHVPANRLHGMADCYKKFIKQPKTDYKRGQFSTRGYFVVQPIYQ
GDE

Download         Length: 252 bp

>T219063 NZ_CP116169:2658921-2659028 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9111.41 Da        Isoelectric Point: 5.0807

>AT219063 WP_105879157.1 NZ_CP084654:4133421-4133672 [Pectobacterium versatile]
MSVQPILANAAVSISDFKKSPNAALKEANGEPVAMLTNGRISGYYVSPETWEALADYQEDIELAKIARSRMKGKRVKVDL
DEL

Download         Length: 252 bp

>AT219063 NZ_CP116169:c2658871-2658808 [Escherichia coli]
TCTGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References