Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 3958072..3958540 Replicon chromosome
Accession NZ_CP084654
Organism Pectobacterium versatile strain SR12

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag LGL95_RS17615 Protein ID WP_230857571.1
Coordinates 3958361..3958540 (+) Length 60 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag LGL95_RS17610 Protein ID WP_103972345.1
Coordinates 3958072..3958278 (+) Length 69 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LGL95_RS17585 (LGL95_17585) 3955316..3956440 - 1125 WP_119879988.1 site-specific integrase -
LGL95_RS17590 (LGL95_17590) 3956558..3956782 - 225 WP_119879989.1 DUF1778 domain-containing protein -
LGL95_RS17595 (LGL95_17595) 3957123..3957365 - 243 WP_109225474.1 helix-turn-helix transcriptional regulator -
LGL95_RS17600 (LGL95_17600) 3957470..3957724 + 255 WP_103942816.1 helix-turn-helix transcriptional regulator -
LGL95_RS17605 (LGL95_17605) 3957809..3958057 + 249 WP_103861239.1 helix-turn-helix transcriptional regulator -
LGL95_RS17610 (LGL95_17610) 3958072..3958278 + 207 WP_103972345.1 type II toxin-antitoxin system antitoxin CcdA Antitoxin
LGL95_RS17615 (LGL95_17615) 3958361..3958540 + 180 WP_230857571.1 CcdB family protein Toxin
LGL95_RS17620 (LGL95_17620) 3958584..3958700 + 117 Protein_3442 transposase -
LGL95_RS17625 (LGL95_17625) 3959063..3959479 + 417 WP_107332409.1 hypothetical protein -
LGL95_RS17630 (LGL95_17630) 3959550..3960845 + 1296 WP_107332408.1 insecticidal delta-endotoxin Cry8Ea1 family protein -
LGL95_RS17635 (LGL95_17635) 3961150..3961302 - 153 WP_103942704.1 helix-turn-helix domain-containing protein -
LGL95_RS17640 (LGL95_17640) 3961350..3961850 - 501 WP_103861241.1 serine acetyltransferase -
LGL95_RS17645 (LGL95_17645) 3961877..3963271 - 1395 WP_039507744.1 DUF4832 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 3958584..3958730 146


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(1-49)

Antitoxin

Post-segregation antitoxin CcdA

(2-68)


Sequences

Toxin        


Download         Length: 60 a.a.        Molecular weight: 6735.86 Da        Isoelectric Point: 5.5067

>T219062 WP_230857571.1 NZ_CP084654:3958361-3958540 [Pectobacterium versatile]
MVIPLIEAHHLSEKVNKTLFPLLRIYGEDYRLMTTELSSVLDEVIGEAVSIPVNRSIHF

Download         Length: 180 bp

>T219062 NZ_CP116169:2658386-2658493 [Escherichia coli]
ATGACGCTCGCGAAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGGATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 69 a.a.        Molecular weight: 7715.53 Da        Isoelectric Point: 5.7997

>AT219062 WP_103972345.1 NZ_CP084654:3958072-3958278 [Pectobacterium versatile]
MKHRISIAVDKDDNQSPNSAGIPISGLVNDEANRIKTEVWKKENREGMENVAKFIAQNSSFADENRNW

Download         Length: 207 bp

>AT219062 NZ_CP116169:c2658333-2658272 [Escherichia coli]
TGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References