Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | ccdAB/CcdA(antitoxin) |
Location | 3942481..3943007 | Replicon | chromosome |
Accession | NZ_CP084654 | ||
Organism | Pectobacterium versatile strain SR12 |
Toxin (Protein)
Gene name | ccdB | Uniprot ID | - |
Locus tag | LGL95_RS17545 | Protein ID | WP_119158864.1 |
Coordinates | 3942702..3943007 (+) | Length | 102 a.a. |
Antitoxin (Protein)
Gene name | ccdA | Uniprot ID | - |
Locus tag | LGL95_RS17540 | Protein ID | WP_119158863.1 |
Coordinates | 3942481..3942699 (+) | Length | 73 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
LGL95_RS17520 (LGL95_17520) | 3938845..3940104 | + | 1260 | WP_130622535.1 | integrase arm-type DNA-binding domain-containing protein | - |
LGL95_RS17525 (LGL95_17525) | 3940557..3940898 | + | 342 | WP_130622536.1 | hypothetical protein | - |
LGL95_RS17530 (LGL95_17530) | 3940950..3941537 | - | 588 | WP_226305879.1 | hypothetical protein | - |
LGL95_RS17535 (LGL95_17535) | 3941679..3942422 | + | 744 | WP_130622538.1 | MobC family replication-relaxation protein | - |
LGL95_RS17540 (LGL95_17540) | 3942481..3942699 | + | 219 | WP_119158863.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin |
LGL95_RS17545 (LGL95_17545) | 3942702..3943007 | + | 306 | WP_119158864.1 | type II toxin-antitoxin system toxin CcdB | Toxin |
LGL95_RS17550 (LGL95_17550) | 3943134..3944393 | - | 1260 | WP_119158865.1 | GIY-YIG nuclease family protein | - |
LGL95_RS17555 (LGL95_17555) | 3944395..3946404 | - | 2010 | WP_193554739.1 | helicase-related protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Integrative and Conjugative Element | - | - | 3938664..3957039 | 18375 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 102 a.a. Molecular weight: 11602.52 Da Isoelectric Point: 5.0980
>T219061 WP_119158864.1 NZ_CP084654:3942702-3943007 [Pectobacterium versatile]
MQFIVYQYKRASHYTMFVDVQSDIVETPKRRMVIPLIESHHLSAKVNKTLFPLIRIDGEEYRLMTTELSSVPVEVIGEVI
ADLSDCADEIKGALNLMFWGI
MQFIVYQYKRASHYTMFVDVQSDIVETPKRRMVIPLIESHHLSAKVNKTLFPLIRIDGEEYRLMTTELSSVPVEVIGEVI
ADLSDCADEIKGALNLMFWGI
Download Length: 306 bp
>T219061 NZ_CP116169:2657850-2657957 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCGGCACCGATCCTGGCGGGGATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCGGCACCGATCCTGGCGGGGATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA
Antitoxin
Download Length: 73 a.a. Molecular weight: 8192.15 Da Isoelectric Point: 7.0135
>AT219061 WP_119158863.1 NZ_CP084654:3942481-3942699 [Pectobacterium versatile]
MKHRVSVTVDKDNYQVLSAAGINISGLVNDAIGKEARRIKAEEWKKENREGMEEVARFIAQNGSFADENRNW
MKHRVSVTVDKDNYQVLSAAGINISGLVNDAIGKEARRIKAEEWKKENREGMEEVARFIAQNGSFADENRNW
Download Length: 219 bp
>AT219061 NZ_CP116169:c2657803-2657737 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT
TGTCTGGTTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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