Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 3001380..3001906 Replicon chromosome
Accession NZ_CP084654
Organism Pectobacterium versatile strain SR12

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LGL95_RS13295 Protein ID WP_107333022.1
Coordinates 3001619..3001906 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LGL95_RS13290 Protein ID WP_107333021.1
Coordinates 3001380..3001619 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LGL95_RS13275 (LGL95_13275) 2997117..2998367 + 1251 WP_226305749.1 integrase domain-containing protein -
LGL95_RS13280 (LGL95_13280) 2998717..3000159 + 1443 WP_043135453.1 IS1182 family transposase -
LGL95_RS13285 (LGL95_13285) 3000456..3001073 + 618 WP_019083811.1 LysE family transporter -
LGL95_RS13290 (LGL95_13290) 3001380..3001619 + 240 WP_107333021.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
LGL95_RS13295 (LGL95_13295) 3001619..3001906 + 288 WP_107333022.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LGL95_RS13300 (LGL95_13300) 3001924..3002283 + 360 WP_107333023.1 hypothetical protein -
LGL95_RS13305 (LGL95_13305) 3002482..3002841 - 360 WP_039475580.1 ankyrin repeat domain-containing protein -
LGL95_RS13310 (LGL95_13310) 3003226..3003696 - 471 WP_219606901.1 GyrI-like domain-containing protein -
LGL95_RS13315 (LGL95_13315) 3003838..3004560 - 723 WP_107333024.1 alpha/beta fold hydrolase -
LGL95_RS13320 (LGL95_13320) 3004804..3005133 - 330 WP_010294841.1 DHCW motif cupin fold protein -
LGL95_RS13325 (LGL95_13325) 3005200..3005736 - 537 WP_107333025.1 rhodanese family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(3-79)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11302.14 Da        Isoelectric Point: 10.1960

>T219057 WP_107333022.1 NZ_CP084654:3001619-3001906 [Pectobacterium versatile]
MSYFLDFDERALKEWRKLGETVRNQFKKKLTDILDAPRIEANKLRGMPDCYKIKLRSAGYRLVYQVQDEKVVVFVVSVGK
RERSEAYDDAIKRLR

Download         Length: 288 bp

>T219057 NZ_CP116169:1819953-1820207 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACGCCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9037.34 Da        Isoelectric Point: 4.5112

>AT219057 WP_107333021.1 NZ_CP084654:3001380-3001619 [Pectobacterium versatile]
MGSINLRIDDDLKTRSYAALEKLGVTPSEALRLTLEYIAENERLPFKQALLSDEDAELVEIVRERLRNPKPVRVTLDDL

Download         Length: 240 bp

>AT219057 NZ_CP116169:1819705-1819956 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTTATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGCTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACAGAAAAGGAC
ATTATTGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References