Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/VapC-VagC |
| Location | 1806099..1806733 | Replicon | chromosome |
| Accession | NZ_CP084654 | ||
| Organism | Pectobacterium versatile strain SR12 | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | - |
| Locus tag | LGL95_RS07940 | Protein ID | WP_103972302.1 |
| Coordinates | 1806329..1806733 (+) | Length | 135 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | C6C2Z8 |
| Locus tag | LGL95_RS07935 | Protein ID | WP_012765080.1 |
| Coordinates | 1806099..1806329 (+) | Length | 77 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LGL95_RS07895 (LGL95_07895) | 1801246..1802133 | + | 888 | WP_211027040.1 | 50S ribosome-binding GTPase | - |
| LGL95_RS07900 (LGL95_07900) | 1802317..1802475 | + | 159 | WP_161569105.1 | hypothetical protein | - |
| LGL95_RS07905 (LGL95_07905) | 1802617..1803078 | + | 462 | WP_125232878.1 | hypothetical protein | - |
| LGL95_RS07910 (LGL95_07910) | 1803136..1803663 | + | 528 | WP_102118412.1 | DUF4234 domain-containing protein | - |
| LGL95_RS07915 (LGL95_07915) | 1803816..1804289 | + | 474 | WP_102118413.1 | DNA repair protein RadC | - |
| LGL95_RS07920 (LGL95_07920) | 1804329..1804664 | + | 336 | WP_125232877.1 | type IV toxin-antitoxin system YeeU family antitoxin | - |
| LGL95_RS07925 (LGL95_07925) | 1804733..1805053 | + | 321 | WP_125232876.1 | TA system toxin CbtA family protein | - |
| LGL95_RS07930 (LGL95_07930) | 1805172..1806005 | + | 834 | WP_125232875.1 | DUF4942 domain-containing protein | - |
| LGL95_RS07935 (LGL95_07935) | 1806099..1806329 | + | 231 | WP_012765080.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin |
| LGL95_RS07940 (LGL95_07940) | 1806329..1806733 | + | 405 | WP_103972302.1 | tRNA(fMet)-specific endonuclease VapC | Toxin |
| LGL95_RS07945 (LGL95_07945) | 1806868..1807077 | + | 210 | WP_226306469.1 | hypothetical protein | - |
| LGL95_RS07950 (LGL95_07950) | 1807069..1807537 | - | 469 | Protein_1540 | integrase | - |
| LGL95_RS07955 (LGL95_07955) | 1807529..1807636 | + | 108 | Protein_1541 | phage holin family protein | - |
| LGL95_RS07960 (LGL95_07960) | 1807636..1808178 | + | 543 | WP_107332647.1 | putative peptidoglycan-binding domain-containing protein | - |
| LGL95_RS07965 (LGL95_07965) | 1808175..1808711 | + | 537 | WP_116361818.1 | hypothetical protein | - |
| LGL95_RS07970 (LGL95_07970) | 1808740..1809618 | + | 879 | WP_103860329.1 | cell envelope biogenesis protein OmpA | - |
| LGL95_RS07975 (LGL95_07975) | 1809746..1809901 | + | 156 | WP_211046524.1 | hypothetical protein | - |
| LGL95_RS07980 (LGL95_07980) | 1810756..1810893 | + | 138 | WP_228925412.1 | YnfU family zinc-binding protein | - |
| LGL95_RS07985 (LGL95_07985) | 1810860..1811123 | + | 264 | WP_127031529.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 1791135..1812136 | 21001 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 135 a.a. Molecular weight: 15045.26 Da Isoelectric Point: 8.0253
>T219056 WP_103972302.1 NZ_CP084654:1806329-1806733 [Pectobacterium versatile]
MLKYLLDTNICIYTIKNKPQEVRDAFYRHYGQFAISSITLMELIYGAEKSVNPEKNLAVIEGFSARLEVQTYGFDAAVHT
GQIRAELARQGTPIGPYDAMLAGHARSAGLILVTNNVREFERVPGLRVENWVGR
MLKYLLDTNICIYTIKNKPQEVRDAFYRHYGQFAISSITLMELIYGAEKSVNPEKNLAVIEGFSARLEVQTYGFDAAVHT
GQIRAELARQGTPIGPYDAMLAGHARSAGLILVTNNVREFERVPGLRVENWVGR
Download Length: 405 bp
>T219056 NZ_CP116169:1819705-1819956 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTTATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGCTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACAGAAAAGGAC
ATTATTGAGTGA
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTTATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGCTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACAGAAAAGGAC
ATTATTGAGTGA
Antitoxin
Download Length: 77 a.a. Molecular weight: 8694.75 Da Isoelectric Point: 4.3063
>AT219056 WP_012765080.1 NZ_CP084654:1806099-1806329 [Pectobacterium versatile]
MEKTTVFKSNRSQAVRLPKAVALPDDVKQVDIVAIGRTRIITPAGESWDSWFEEDGVTPDFMITREQPDDQIREDF
MEKTTVFKSNRSQAVRLPKAVALPDDVKQVDIVAIGRTRIITPAGESWDSWFEEDGVTPDFMITREQPDDQIREDF
Download Length: 231 bp
>AT219056 NZ_CP116169:1819953-1820207 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACGCCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACGCCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|