Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ykfI-yfjZ/CbtA-CbeA
Location 1804329..1805053 Replicon chromosome
Accession NZ_CP084654
Organism Pectobacterium versatile strain SR12

Toxin (Protein)


Gene name ykfI Uniprot ID -
Locus tag LGL95_RS07925 Protein ID WP_125232876.1
Coordinates 1804733..1805053 (+) Length 107 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag LGL95_RS07920 Protein ID WP_125232877.1
Coordinates 1804329..1804664 (+) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LGL95_RS07890 (LGL95_07890) 1800128..1801150 + 1023 WP_226306303.1 hypothetical protein -
LGL95_RS07895 (LGL95_07895) 1801246..1802133 + 888 WP_211027040.1 50S ribosome-binding GTPase -
LGL95_RS07900 (LGL95_07900) 1802317..1802475 + 159 WP_161569105.1 hypothetical protein -
LGL95_RS07905 (LGL95_07905) 1802617..1803078 + 462 WP_125232878.1 hypothetical protein -
LGL95_RS07910 (LGL95_07910) 1803136..1803663 + 528 WP_102118412.1 DUF4234 domain-containing protein -
LGL95_RS07915 (LGL95_07915) 1803816..1804289 + 474 WP_102118413.1 DNA repair protein RadC -
LGL95_RS07920 (LGL95_07920) 1804329..1804664 + 336 WP_125232877.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
LGL95_RS07925 (LGL95_07925) 1804733..1805053 + 321 WP_125232876.1 TA system toxin CbtA family protein Toxin
LGL95_RS07930 (LGL95_07930) 1805172..1806005 + 834 WP_125232875.1 DUF4942 domain-containing protein -
LGL95_RS07935 (LGL95_07935) 1806099..1806329 + 231 WP_012765080.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
LGL95_RS07940 (LGL95_07940) 1806329..1806733 + 405 WP_103972302.1 tRNA(fMet)-specific endonuclease VapC -
LGL95_RS07945 (LGL95_07945) 1806868..1807077 + 210 WP_226306469.1 hypothetical protein -
LGL95_RS07950 (LGL95_07950) 1807069..1807537 - 469 Protein_1540 integrase -
LGL95_RS07955 (LGL95_07955) 1807529..1807636 + 108 Protein_1541 phage holin family protein -
LGL95_RS07960 (LGL95_07960) 1807636..1808178 + 543 WP_107332647.1 putative peptidoglycan-binding domain-containing protein -
LGL95_RS07965 (LGL95_07965) 1808175..1808711 + 537 WP_116361818.1 hypothetical protein -
LGL95_RS07970 (LGL95_07970) 1808740..1809618 + 879 WP_103860329.1 cell envelope biogenesis protein OmpA -
LGL95_RS07975 (LGL95_07975) 1809746..1809901 + 156 WP_211046524.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1791135..1812136 21001


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-105)

Antitoxin

Antitoxin CbeA

(7-106)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12101.85 Da        Isoelectric Point: 4.7768

>T219055 WP_125232876.1 NZ_CP084654:1804733-1805053 [Pectobacterium versatile]
MQTTPAIPSREDNPCPSPIAAWQQLLTYLMEKHYGLTLNDTPFCEENVIQEHIDVGITLVNAVNFLVEKYELVRIDRNGF
NWQEQSLFLTAVDVLRARRATGLLKA

Download         Length: 321 bp

>T219055 NZ_CP116169:1341274-1341672 [Escherichia coli]
ATGCTGAAATTCATGCTGGATACCAATATCTGTATTTTCACTATTAAGAATAAACCAGTACATGTCAGAGAGCGGTTTAA
CCTGAATTCTGGCCGGATGTGTATAAGTTCTGTAACATTGATGGAGCTTATCTATGGGGCAGAAAAAAGTCAGATGCCAG
AACGCAATTTGGCGGTTATTGAAGGTTTCGTATCTCGTTTGGTAGTGCTTGATTATGATAGTGCTGCTGCGACGCATACC
GGGCAAATCAGGGCCGAGCTTGCCCGGCAGGGAAGGCCTGTTGGACCTTTTGACCAGATGATAGCGGGACATGCTCGCAG
TCGCGGTTTGATTGTGGTTACCAACAATACCCGAGAGTTTGAGCGAGTGGCGGGAATCAGACTAGAAGACTGGAGCTAA

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12335.97 Da        Isoelectric Point: 5.5934

>AT219055 WP_125232877.1 NZ_CP084654:1804329-1804664 [Pectobacterium versatile]
MPSSDTPEWGLKCAVTPRFGARLVQEGNRLHYLADRAGFIGTFSQAEARSLEHVFPELIKQLEQKLRTGELNPCQQGCIV
LHCNEWTCEADTLGSFGYVYIAIYPSSAATQ

Download         Length: 336 bp

>AT219055 NZ_CP116169:1341047-1341274 [Escherichia coli]
ATGGAAACTACTGTATTTTTAAGTAATCGCAGTCAGGCCGTCAGATTACCGAAAGCGGTCGCTCTGCCAGAAGACGTTAA
GAAAGTAGAAATTATTGCGATTGGTCGTACAAGAATCATCACTCCCGCCGGTGAGTCCTGGGACAGTTGGTTTGATGGCG
AAAATGTGAGTGCGGATTTTATGGATATCCGTGATCAACCCGCAATGCAGGAAAGGGAATCATTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References