Detailed information of TA system TA219054

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): ykfI-yfjZ/CbtA-CbeA
• Location: 1473423..1474147
• Replicon: chromosome
• Accession: NZ_CP084654
• Organism: Pectobacterium versatile strain SR12

Toxin (Protein)

• Gene name: ykfI
• Uniprot ID: -
• Locus tag: LGL95_RS06585
• Protein ID: WP_226306243.1
• Coordinates: 1473423..1473743 (-)
• Length: 107 a.a.

Antitoxin (Protein)

• Gene name: yfjZ
• Uniprot ID: -
• Locus tag: LGL95_RS06590
• Protein ID: WP_226306244.1
• Coordinates: 1473812..1474147 (-)
• Length: 112 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LGL95_RS06555 (LGL95_06555)	1468858..1469736	+	879	WP_109224832.1	TauD/TfdA family dioxygenase	-
LGL95_RS06560 (LGL95_06560)	1469733..1471166	+	1434	WP_226306239.1	FAD-binding protein	-
LGL95_RS06565 (LGL95_06565)	1471257..1471403	-	147	Protein_1269	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	-
LGL95_RS06570 (LGL95_06570)	1471743..1472147	-	405	WP_226306240.1	tRNA(fMet)-specific endonuclease VapC	-
LGL95_RS06575 (LGL95_06575)	1472147..1472377	-	231	WP_226306241.1	type II toxin-antitoxin system VapB family antitoxin	-
LGL95_RS06580 (LGL95_06580)	1472472..1473305	-	834	WP_226306242.1	DUF4942 domain-containing protein	-
LGL95_RS06585 (LGL95_06585)	1473423..1473743	-	321	WP_226306243.1	TA system toxin CbtA family protein	Toxin
LGL95_RS06590 (LGL95_06590)	1473812..1474147	-	336	WP_226306244.1	type IV toxin-antitoxin system YeeU family antitoxin	Antitoxin
LGL95_RS06595 (LGL95_06595)	1474187..1474660	-	474	WP_226306245.1	DNA repair protein RadC	-
LGL95_RS06600 (LGL95_06600)	1474712..1475533	-	822	WP_226306246.1	DUF932 domain-containing protein	-
LGL95_RS06605 (LGL95_06605)	1475615..1475827	-	213	WP_226306247.1	hypothetical protein	-
LGL95_RS06610 (LGL95_06610)	1475860..1476267	-	408	WP_226306248.1	hypothetical protein	-
LGL95_RS06615 (LGL95_06615)	1476310..1476675	-	366	WP_226306249.1	hypothetical protein	-
LGL95_RS06620 (LGL95_06620)	1476773..1477450	-	678	WP_193401441.1	WYL domain-containing protein	-
LGL95_RS06625 (LGL95_06625)	1477505..1478236	-	732	WP_208231464.1	DUF3944 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	1464173..1490425	26252

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• CbtA toxin of type IV toxin-antitoxin system (1-105)

Antitoxin

• Antitoxin CbeA (7-106)

Sequences

Toxin

Protein

• Length: 107 a.a.
• Molecular weight: 12079.95 Da
• Isoelectric Point: 5.6713

>T219054 WP_226306243.1 NZ_CP084654:c1473743-1473423 [Pectobacterium versatile]
MQISPAIPPREDIPRPLPIAVWQQLLAYLLEKHYGLTLNDTPFCEENVIQAHIDAGVTLVNAVNFLVERYELVRIDRNGF
NWQEQSPFLTAVDVLRARRATGLLKA

Nucleotide

• Length: 321 bp

>T219054 NZ_CP116169:1016851-1017186 [Escherichia coli]
ATGGTAAGCCGATACGTACCCGATATGGGCGATCTGATTTGGGTTGATTTTGACCCGACAAAAGGTAGCGAGCAAGCTGG
ACATCGTCCAGCTGTTGTCCTGAGTCCTTTCATGTACAACAACAAAACAGGTATGTGTCTGTGTGTTCCTTATACAACGC
AATCAAAAGGATATCCGTTCGAAGTTGTTTTATCCGGTCAGGAACGTGATGGCGTAGCGTTAGCTGATCAGGTAAAAAGT
ATCGCCTGGCGGGCAAGAGGAGCAACGAAGAAAGGAACAGTTGCCCCAGAGGAATTACAACTCATTAAAGCCAAAATTAA
CGTACTGATTGGGTAG

Antitoxin

Protein

• Length: 112 a.a.
• Molecular weight: 12477.18 Da
• Isoelectric Point: 5.5858

>AT219054 WP_226306244.1 NZ_CP084654:c1474147-1473812 [Pectobacterium versatile]
MPLSDSPEWGLKRAVTPQFGARLVQEGHYLHYLADRASIVGTFSKTEAQSLECCFSELIKLLEQKLRTGELNPRQQNCVT
LYCNDWTCEADTLGSFGYVYIAIYPSLAATH

Nucleotide

• Length: 336 bp

>AT219054 NZ_CP116169:1016603-1016851 [Escherichia coli]
ATGATCCACAGTAGCGTAAAGCGTTGGGGAAATTCACCGGCGGTGCGGATCCCGGCTACGTTAATGCAGGCGCTCAATCT
GAATATTGATGATGAAGTGAAGATTGACCTGGTGGATGGCAAATTAATTATTGAGCCAGTGCGTAAAGAGCCCGTATTTA
CGCTTGCTGAACTGGTCAACGACATCACGCCGGAAAACCTCCACGAGAATATCGACTGGGGAGAGCCGAAAGATAAGGAA
GTCTGGTAA