Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | tad-ata/COG5606-COG4679 |
| Location | 1371153..1371816 | Replicon | chromosome |
| Accession | NZ_CP084654 | ||
| Organism | Pectobacterium versatile strain SR12 | ||
Toxin (Protein)
| Gene name | tad | Uniprot ID | - |
| Locus tag | LGL95_RS06125 | Protein ID | WP_103971625.1 |
| Coordinates | 1371472..1371816 (-) | Length | 115 a.a. |
Antitoxin (Protein)
| Gene name | ata | Uniprot ID | - |
| Locus tag | LGL95_RS06120 | Protein ID | WP_039538898.1 |
| Coordinates | 1371153..1371470 (-) | Length | 106 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LGL95_RS06090 (LGL95_06090) | 1366685..1367551 | - | 867 | WP_223878567.1 | NADP-dependent oxidoreductase | - |
| LGL95_RS06095 (LGL95_06095) | 1367726..1368328 | + | 603 | WP_103941405.1 | TetR/AcrR family transcriptional regulator | - |
| LGL95_RS06100 (LGL95_06100) | 1368420..1368758 | - | 339 | WP_010279998.1 | putative addiction module antidote protein | - |
| LGL95_RS06105 (LGL95_06105) | 1368763..1369089 | - | 327 | WP_164498029.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| LGL95_RS06110 (LGL95_06110) | 1369559..1370137 | + | 579 | WP_103183417.1 | hypothetical protein | - |
| LGL95_RS06115 (LGL95_06115) | 1370723..1370938 | + | 216 | WP_226306233.1 | helix-turn-helix transcriptional regulator | - |
| LGL95_RS06120 (LGL95_06120) | 1371153..1371470 | - | 318 | WP_039538898.1 | helix-turn-helix transcriptional regulator | Antitoxin |
| LGL95_RS06125 (LGL95_06125) | 1371472..1371816 | - | 345 | WP_103971625.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| LGL95_RS06130 (LGL95_06130) | 1372048..1373076 | - | 1029 | WP_103862506.1 | helix-turn-helix domain-containing protein | - |
| LGL95_RS06135 (LGL95_06135) | 1373242..1374015 | + | 774 | WP_188247222.1 | alpha/beta hydrolase | - |
| LGL95_RS06140 (LGL95_06140) | 1374050..1374670 | + | 621 | WP_188247230.1 | FMN-dependent NADH-azoreductase | - |
| LGL95_RS06145 (LGL95_06145) | 1374710..1375018 | + | 309 | WP_103940851.1 | YciI family protein | - |
| LGL95_RS06150 (LGL95_06150) | 1375128..1376258 | - | 1131 | WP_107333251.1 | linear amide C-N hydrolase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 115 a.a. Molecular weight: 12446.15 Da Isoelectric Point: 9.7991
>T219052 WP_103971625.1 NZ_CP084654:c1371816-1371472 [Pectobacterium versatile]
MKSLYWVGSSKKDLQSLPADVQDVFGYALHLAQTGGKHTQAKPLKGFGGAGVLEVVEDYIGDTYRAVYTVRFGEAVYVLH
AFQKKSSSGIATQKPDMNTIRERLKTAENHAKGA
MKSLYWVGSSKKDLQSLPADVQDVFGYALHLAQTGGKHTQAKPLKGFGGAGVLEVVEDYIGDTYRAVYTVRFGEAVYVLH
AFQKKSSSGIATQKPDMNTIRERLKTAENHAKGA
Download Length: 345 bp
>T219052 NZ_CP116169:c595156-594692 [Escherichia coli]
ATGGATTTTCCACAAAGGGTTAATGGTTGGGCGCTATATGCTCATCCCTGTTTTCAGGAAACCTACGACGCTTTAGTTGC
CGAAGTCGAGACATTAAAGGGAAAAGATCCTGAAAATTATCAGAGAAAAGCCGCCACAAAGTTATTGGCGGTAGTCCATA
AAGTGATTGAGGAGCATATCACGGTCAATCCATCATCACCGGCATTCCGTCATGGCAAGTCGTTAGGCTCTGGGAAAAAT
AAAGACTGGTCACGGGTAAAATTTGGTGCTGGTCGTTATCGTTTCTTCTTTCGTTATAGTGAAAAAGAGAAAGTCATCAT
TCTGGGATGGATGAACGATGAAAACACTCTGCGCACCTACGGTAAAAAAACAGATGCCTATACCGTATTCAGCAAAATGT
TAAAAAGAGGACATCCTCCTGCCGACTGGGAAAGCCTCACCCAAGAGACAGAAGAAAACCATTGA
ATGGATTTTCCACAAAGGGTTAATGGTTGGGCGCTATATGCTCATCCCTGTTTTCAGGAAACCTACGACGCTTTAGTTGC
CGAAGTCGAGACATTAAAGGGAAAAGATCCTGAAAATTATCAGAGAAAAGCCGCCACAAAGTTATTGGCGGTAGTCCATA
AAGTGATTGAGGAGCATATCACGGTCAATCCATCATCACCGGCATTCCGTCATGGCAAGTCGTTAGGCTCTGGGAAAAAT
AAAGACTGGTCACGGGTAAAATTTGGTGCTGGTCGTTATCGTTTCTTCTTTCGTTATAGTGAAAAAGAGAAAGTCATCAT
TCTGGGATGGATGAACGATGAAAACACTCTGCGCACCTACGGTAAAAAAACAGATGCCTATACCGTATTCAGCAAAATGT
TAAAAAGAGGACATCCTCCTGCCGACTGGGAAAGCCTCACCCAAGAGACAGAAGAAAACCATTGA
Antitoxin
Download Length: 106 a.a. Molecular weight: 11448.48 Da Isoelectric Point: 10.6133
>AT219052 WP_039538898.1 NZ_CP084654:c1371470-1371153 [Pectobacterium versatile]
MSQDIEVSSGNVYADLGNLHAEDMLVKAQLATLISSIIKSRRLTQAEAAKLLGMPQPKLSNLLRGQFRGISETKMLECLT
KLGRDIQIVVGKPRRTPGSVKVVFA
MSQDIEVSSGNVYADLGNLHAEDMLVKAQLATLISSIIKSRRLTQAEAAKLLGMPQPKLSNLLRGQFRGISETKMLECLT
KLGRDIQIVVGKPRRTPGSVKVVFA
Download Length: 318 bp
>AT219052 NZ_CP116169:c595491-595156 [Escherichia coli]
ATGCCCGCTAATGCTCGCTCTCACGCTGTACTGACCACTGAATCAAAGGTCACGATACGCGGACAAACAACTATCCCCGC
GCCAGTGCGTGAGGCCTTAAAACTGAAGCCAGGCCAGGACAGCATTCATTACGAAATTCTGCCTGGTGGGCAAGTCTTTA
TGTGCCGACTGGGAGATGAACAGGAGGATCATACTATGAATGCATTTTTGCGTTTTCTGGATGCAGATATCCAGAACAAC
CCGCAAAAAACTCGTCCATTCAACATTCAACAAGGAAAGAAACTTGTCGCTGGCATGGACGTCAACATTGATGATGAGAT
TGGCGACGACGAATAA
ATGCCCGCTAATGCTCGCTCTCACGCTGTACTGACCACTGAATCAAAGGTCACGATACGCGGACAAACAACTATCCCCGC
GCCAGTGCGTGAGGCCTTAAAACTGAAGCCAGGCCAGGACAGCATTCATTACGAAATTCTGCCTGGTGGGCAAGTCTTTA
TGTGCCGACTGGGAGATGAACAGGAGGATCATACTATGAATGCATTTTTGCGTTTTCTGGATGCAGATATCCAGAACAAC
CCGCAAAAAACTCGTCCATTCAACATTCAACAAGGAAAGAAACTTGTCGCTGGCATGGACGTCAACATTGATGATGAGAT
TGGCGACGACGAATAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|