Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 2902263..2902932 Replicon chromosome
Accession NZ_CP084652
Organism Yersinia ruckeri strain 16Y0180

Toxin (Protein)


Gene name cptA Uniprot ID A0A380QS17
Locus tag LGL93_RS13325 Protein ID WP_038241020.1
Coordinates 2902263..2902685 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag LGL93_RS13330 Protein ID WP_004719196.1
Coordinates 2902666..2902932 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LGL93_RS13305 (LGL93_13340) 2898102..2899835 - 1734 WP_004719191.1 single-stranded-DNA-specific exonuclease RecJ -
LGL93_RS13310 (LGL93_13345) 2899842..2900558 - 717 WP_004719192.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
LGL93_RS13315 (LGL93_13350) 2900590..2901489 - 900 WP_004719193.1 site-specific tyrosine recombinase XerD -
LGL93_RS13320 (LGL93_13355) 2901597..2902115 + 519 WP_038241022.1 flavodoxin FldB -
LGL93_RS13325 (LGL93_13360) 2902263..2902685 - 423 WP_038241020.1 protein YgfX Toxin
LGL93_RS13330 (LGL93_13365) 2902666..2902932 - 267 WP_004719196.1 FAD assembly factor SdhE Antitoxin
LGL93_RS13335 (LGL93_13370) 2903226..2904218 + 993 WP_038241018.1 tRNA-modifying protein YgfZ -
LGL93_RS13340 (LGL93_13375) 2904357..2905031 - 675 WP_049687854.1 hemolysin III family protein -
LGL93_RS13345 (LGL93_13380) 2905339..2905595 + 257 Protein_2591 HD domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 16451.41 Da        Isoelectric Point: 11.1478

>T219047 WP_038241020.1 NZ_CP084652:c2902685-2902263 [Yersinia ruckeri]
VAQWRCDLRVSWRTQLFSLLVHGVLVLLTLVVPWPDGFTPLWLILLTLVVFECIRSQKNITSRQGEIRLKAGNLLIWKWQ
EWTLVRPPWITRYGVLLSLQGAGSRRRKRIWLASDSMSEEKWRELCLILRHTFDSAAGRE

Download         Length: 423 bp

>T219047 NZ_CP116168:c56884-56735 [Escherichia coli]
ATGACGAAATATGCCCTTATCGGGTTGCTCGCCGTGTGCGCCACGGTGTTGTGTTTTTCACTGATATTCAGGGAACGGTT
ATGTGAACTGAATATTCACAGGGGAAATACAGTGGTGCAGGTAACTCTGGCCTACGAAGCACGGAAGTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10532.09 Da        Isoelectric Point: 6.7185

>AT219047 WP_004719196.1 NZ_CP084652:c2902932-2902666 [Yersinia ruckeri]
MEIDNKARIHWACRRGMRELDISIMPFFEHEYDTLNDNDKRVFIRLLTSDDPDLFNWLMNHGEPQDSELKRMVKLIQTRN
KARGPVAM

Download         Length: 267 bp

>AT219047 NZ_CP116168:56928-56989 [Escherichia coli]
TTAAGGTACTTCATGCAGACCTCACGAGTTAATGGATTAACGAGTGGGGTCTTCGCATTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A380QS17

Antitoxin

Source ID Structure

References