Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 1882267..1883185 Replicon chromosome
Accession NZ_CP084647
Organism Yersinia ruckeri strain 17Y0157

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag LGL89_RS08425 Protein ID WP_038242633.1
Coordinates 1882727..1883185 (+) Length 153 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag LGL89_RS08420 Protein ID WP_234054664.1
Coordinates 1882267..1882713 (+) Length 149 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LGL89_RS08400 (LGL89_08425) 1877965..1878669 + 705 WP_004717543.1 murein tripeptide amidase MpaA -
LGL89_RS08405 (LGL89_08430) 1878680..1879654 - 975 WP_038275966.1 L-Ala-D/L-Glu epimerase -
LGL89_RS08410 (LGL89_08435) 1879804..1880307 + 504 WP_004717547.1 thiol peroxidase -
LGL89_RS08415 (LGL89_08440) 1880342..1881949 - 1608 WP_038251390.1 transcriptional regulator TyrR -
LGL89_RS08420 (LGL89_08445) 1882267..1882713 + 447 WP_234054664.1 DUF2384 domain-containing protein Antitoxin
LGL89_RS08425 (LGL89_08450) 1882727..1883185 + 459 WP_038242633.1 RES domain-containing protein Toxin
LGL89_RS08430 (LGL89_08455) 1883189..1884247 - 1059 WP_038242635.1 YcjF family protein -
LGL89_RS08435 (LGL89_08460) 1884244..1885641 - 1398 WP_004717556.1 YcjX family protein -
LGL89_RS08440 (LGL89_08465) 1885622..1885864 - 243 WP_087931058.1 phage shock protein PspD -
LGL89_RS08445 (LGL89_08470) 1885928..1886287 - 360 WP_004717559.1 envelope stress response membrane protein PspC -
LGL89_RS08450 (LGL89_08475) 1886287..1886514 - 228 WP_038242637.1 envelope stress response membrane protein PspB -
LGL89_RS08455 (LGL89_08480) 1886598..1887263 - 666 WP_038275968.1 phage shock protein PspA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(3-147)

Antitoxin

Antitoxin Xre-like, helix-turn-helix domain

(36-90)


Sequences

Toxin        


Download         Length: 153 a.a.        Molecular weight: 17072.55 Da        Isoelectric Point: 6.6384

>T218996 WP_038242633.1 NZ_CP084647:1882727-1883185 [Yersinia ruckeri]
VMLYRIVHNRYLATAWTGYGAETYGGRWNHKGHAAIYLASSVSLAMLETLVHVEDSATLNDFNLFQITIPDNAIMVLQQQ
DWPRGWRDDPTPVATMDIGTEWIGSVSSVGLLVPSTLVPLERNMLVNPKHRDFASCLKSINPLTFSFDPRLK

Download         Length: 459 bp

>T218996 NZ_CP116152:c3965059-3964772 [Escherichia coli]
ATGCCAATGGAGTTTGAATGGGATGAAAACAAGGCCAAAAGTAATCGGGTGAAACATGGCATCCGCTTTGAAGATGCGGT
GTTATTGTTTGATGATCCACAACATTTGTCACAGCAAGAACGCATAGAAAACGGTGAGTATCGCTGGCAGACAATCGGCC
TGGTTTACGGCATCGTGGTTATTCTGGTTGCGCATACCATCCGTTTCGAAAGCGGAAATGAAATTATTCGAATCATCAGT
GCACGAAAAGCAGATCGTAAAGAGAGGAATCGCTATGAGCATGGTTAA

Antitoxin


Download         Length: 149 a.a.        Molecular weight: 16388.84 Da        Isoelectric Point: 8.0956

>AT218996 WP_234054664.1 NZ_CP084647:1882267-1882713 [Yersinia ruckeri]
MRTYHPSPMAKVSALWREIGLPASRGTALVDSIKLGFTVDVIDTIHLWADMPKSEILRATGIPSRSLTRRRTHDGRFTPE
ESERIARFVRVMDAAVDLFGGDRTKATAWISMPVKGLGNRTPDSLLETETGALEICDLIGRLEHGVFS

Download         Length: 447 bp

>AT218996 NZ_CP116152:c3964785-3964483 [Escherichia coli]
ATGAGCATGGTTAAACATAAACGAGGGACCTCCTCTACACTCGATGTGCAGCATGAGGCCGAACTGAAGGCGCTGACGAA
TAAATCCGACGAAGATATTGATTACAGTGATATCCCACCTTCCAGCGATGAGCAATGGTCTAACGCCGAACGCGGTAAGT
TTTATCGGCCATTGAAAACTCAGGCTTCGGTGCGTATTGATGCTGATGTGATGGAATGGTTGAAGCGACCAGGTAAAGGC
TATCAAACTCGCCTGAACGCAATTTTACGTGAAGCGATGCTGCGCGATCAGAACAAAAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References