Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | sanaTA/AbiEii-DUF6088 |
| Location | 458570..459908 | Replicon | chromosome |
| Accession | NZ_CP084647 | ||
| Organism | Yersinia ruckeri strain 17Y0157 | ||
Toxin (Protein)
| Gene name | sanaT | Uniprot ID | - |
| Locus tag | LGL89_RS02100 | Protein ID | WP_038275283.1 |
| Coordinates | 458958..459908 (+) | Length | 317 a.a. |
Antitoxin (Protein)
| Gene name | sanaA | Uniprot ID | A0A848MNT5 |
| Locus tag | LGL89_RS02095 | Protein ID | WP_038245317.1 |
| Coordinates | 458570..458965 (+) | Length | 132 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LGL89_RS02045 (LGL89_02055) | 454029..454418 | + | 390 | WP_096823270.1 | restriction endonuclease subunit S | - |
| LGL89_RS02050 (LGL89_02060) | 454542..455117 | + | 576 | WP_234049239.1 | DarT ssDNA thymidine ADP-ribosyltransferase family protein | - |
| LGL89_RS02055 (LGL89_02065) | 455120..455776 | + | 657 | WP_096823271.1 | DUF4433 domain-containing protein | - |
| LGL89_RS02060 (LGL89_02070) | 455773..456840 | + | 1068 | WP_038245756.1 | macro domain-containing protein | - |
| LGL89_RS02065 (LGL89_02075) | 456861..457127 | + | 267 | Protein_399 | hypothetical protein | - |
| LGL89_RS02070 (LGL89_02080) | 457146..457544 | - | 399 | Protein_400 | integrase core domain-containing protein | - |
| LGL89_RS02075 (LGL89_02085) | 457543..457839 | + | 297 | Protein_401 | integrase core domain-containing protein | - |
| LGL89_RS02080 (LGL89_02090) | 457868..457973 | - | 106 | Protein_402 | transposase | - |
| LGL89_RS02085 (LGL89_02095) | 457987..458115 | - | 129 | Protein_403 | helix-turn-helix domain-containing protein | - |
| LGL89_RS02090 (LGL89_02100) | 458265..458495 | + | 231 | Protein_404 | DUF4942 domain-containing protein | - |
| LGL89_RS02095 (LGL89_02105) | 458570..458965 | + | 396 | WP_038245317.1 | DUF6088 family protein | Antitoxin |
| LGL89_RS02100 (LGL89_02110) | 458958..459908 | + | 951 | WP_038275283.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | Toxin |
| LGL89_RS02105 (LGL89_02115) | 460279..460404 | + | 126 | Protein_407 | antirestriction protein | - |
| LGL89_RS02110 (LGL89_02120) | 460430..460603 | + | 174 | Protein_408 | type IV toxin-antitoxin system YeeU family antitoxin | - |
| LGL89_RS02115 (LGL89_02125) | 461206..462360 | + | 1155 | WP_038245380.1 | N-acetylneuraminate epimerase | - |
| LGL89_RS02120 (LGL89_02130) | 462408..463100 | + | 693 | WP_038245321.1 | oligogalacturonate-specific porin KdgM family protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | flank | IS/Tn | - | - | 457591..457839 | 248 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 317 a.a. Molecular weight: 36088.43 Da Isoelectric Point: 4.5996
>T218994 WP_038275283.1 NZ_CP084647:458958-459908 [Yersinia ruckeri]
MDDLTKLFPDVADALGIESVSIVEKDYYIVELLRLLQPMDFDTHQLVFAGGTALSKAGISLNRMSEDVDIKLVPVAGFTQ
QYSRGQRKDIRKGIIRTVIETITASGTFRMDEGYPKVTRDEYRYNEIPVRYPQEYVQVPCLRPFIKLELMETDLLEAAEN
RAISSLVMDLTKKGEVVRAFPCATIGSTQAEKLISMMRRTAASMRDVERAVDESLVRHIYDNFCIVREKGADVPVLKQFV
QECIEQDIERYGAQYPEFCESPVEELKMGLEELVSNPVYKERYLQFVTPMVFGESHVSWEEAYACFRKTVLDVVDA
MDDLTKLFPDVADALGIESVSIVEKDYYIVELLRLLQPMDFDTHQLVFAGGTALSKAGISLNRMSEDVDIKLVPVAGFTQ
QYSRGQRKDIRKGIIRTVIETITASGTFRMDEGYPKVTRDEYRYNEIPVRYPQEYVQVPCLRPFIKLELMETDLLEAAEN
RAISSLVMDLTKKGEVVRAFPCATIGSTQAEKLISMMRRTAASMRDVERAVDESLVRHIYDNFCIVREKGADVPVLKQFV
QECIEQDIERYGAQYPEFCESPVEELKMGLEELVSNPVYKERYLQFVTPMVFGESHVSWEEAYACFRKTVLDVVDA
Download Length: 951 bp
>T218994 NZ_CP116152:3381102-3381320 [Escherichia coli]
ATGTCCGAAAAACCTTTAACGAAAACCGATTATTTAATGCGTTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGTGT
TATCGAGAAAAATAAATACGAATTATCAGATAATGAACTGGCGGTATTTTACTCAGCCGCAGATCACCGCCTCGCCGAAT
TGACCATGAATAAACTGTACGACAAGATCCCTTCCTCAGTATGGAAATTTATTCGCTAA
ATGTCCGAAAAACCTTTAACGAAAACCGATTATTTAATGCGTTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGTGT
TATCGAGAAAAATAAATACGAATTATCAGATAATGAACTGGCGGTATTTTACTCAGCCGCAGATCACCGCCTCGCCGAAT
TGACCATGAATAAACTGTACGACAAGATCCCTTCCTCAGTATGGAAATTTATTCGCTAA
Antitoxin
Download Length: 132 a.a. Molecular weight: 14406.76 Da Isoelectric Point: 11.0360
>AT218994 WP_038245317.1 NZ_CP084647:458570-458965 [Yersinia ruckeri]
MTTKARIQLRLKRSKRYVFTRDDFKDLAGYDQIGRALRELVKEGQLLKVGYGVYTKARQNVITGKLMPAAPGGSAAVVIE
ALERLKVDYRLVGATSAYNSGKSTQIPASLEIKTSPRFKRTLSVGSSKLNG
MTTKARIQLRLKRSKRYVFTRDDFKDLAGYDQIGRALRELVKEGQLLKVGYGVYTKARQNVITGKLMPAAPGGSAAVVIE
ALERLKVDYRLVGATSAYNSGKSTQIPASLEIKTSPRFKRTLSVGSSKLNG
Download Length: 396 bp
>AT218994 NZ_CP116152:3380702-3381076 [Escherichia coli]
ATGGATGAATACTCACCCAAAAGACATGATATCGCACAGCTTAAGTTTCTCTGTGAAACCCTGTATCATGACTGCCTTGC
AAACCTTGAAGAAAGCAATCATGGCTGGGTAAACGACCCAACCTCGGCGATCAACCTCCAGTTGAATGAACTGATTGAGC
ATATTGCGACCTTCGCACTTAATTACAAAATTAAGTATAATGAAGACAATAAGCTCATTGAGCAGATCGACGAATATCTG
GATGACACCTTTATGTTGTTCAGTAGTTATGGTATTAATATGCAGGATCTTCAGAAATGGCGGAAGTCAGGTAATCGACT
ATTCCGTTGTTTTGTCAATGCGACGAAAGAGAATCCTGCGAGTTTATCTTGTTAG
ATGGATGAATACTCACCCAAAAGACATGATATCGCACAGCTTAAGTTTCTCTGTGAAACCCTGTATCATGACTGCCTTGC
AAACCTTGAAGAAAGCAATCATGGCTGGGTAAACGACCCAACCTCGGCGATCAACCTCCAGTTGAATGAACTGATTGAGC
ATATTGCGACCTTCGCACTTAATTACAAAATTAAGTATAATGAAGACAATAAGCTCATTGAGCAGATCGACGAATATCTG
GATGACACCTTTATGTTGTTCAGTAGTTATGGTATTAATATGCAGGATCTTCAGAAATGGCGGAAGTCAGGTAATCGACT
ATTCCGTTGTTTTGTCAATGCGACGAAAGAGAATCCTGCGAGTTTATCTTGTTAG
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|