Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeV-yfjZ/CbtA-CbeA
Location 447131..447867 Replicon chromosome
Accession NZ_CP084647
Organism Yersinia ruckeri strain 17Y0157

Toxin (Protein)


Gene name yeeV Uniprot ID -
Locus tag LGL89_RS02000 Protein ID WP_045844421.1
Coordinates 447131..447502 (+) Length 124 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag LGL89_RS02005 Protein ID WP_045844422.1
Coordinates 447499..447867 (+) Length 123 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LGL89_RS01975 (LGL89_01985) 442959..443396 + 438 WP_045844416.1 hypothetical protein -
LGL89_RS01980 (LGL89_01990) 443416..444684 + 1269 WP_045844417.1 hypothetical protein -
LGL89_RS01985 (LGL89_01995) 444907..445344 + 438 WP_045844418.1 hypothetical protein -
LGL89_RS01990 (LGL89_02000) 445427..446248 + 822 WP_045844419.1 DUF932 domain-containing protein -
LGL89_RS01995 (LGL89_02005) 446608..447039 + 432 WP_045844420.1 antirestriction protein -
LGL89_RS02000 (LGL89_02010) 447131..447502 + 372 WP_045844421.1 TA system toxin CbtA family protein Toxin
LGL89_RS02005 (LGL89_02015) 447499..447867 + 369 WP_045844422.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
LGL89_RS02010 (LGL89_02020) 448333..449589 + 1257 Protein_388 integrase arm-type DNA-binding domain-containing protein -
LGL89_RS02015 (LGL89_02025) 449661..449966 + 306 WP_234054908.1 hypothetical protein -
LGL89_RS02020 (LGL89_02030) 450017..451273 - 1257 WP_234054909.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 440574..456840 16266


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(12-101)

Antitoxin

Antitoxin CbeA

(10-108)


Sequences

Toxin        


Download         Length: 124 a.a.        Molecular weight: 13580.72 Da        Isoelectric Point: 6.6362

>T218991 WP_045844421.1 NZ_CP084647:447131-447502 [Yersinia ruckeri]
MKPCPITPGALPVPVIYQQLLAFLLEHHYGLSLNDTPYHDEQAIAQQIEQGISVGDTINTLVEKYALVRIGRNGFSVLAQ
DPMLSKGDIVRARQALGLWRAHFPPTLLHPTEPLNPIPQSPLT

Download         Length: 372 bp

>T218991 NZ_CP116152:c2397287-2397111 [Escherichia coli]
GTGAAACAAAGCGAGTTCAGACGTTGGCTCGAATCTCAGGGCGTCGATGTAGCGAATGGCAGCAACCATTTGAAACTCAG
GTTTCATGGGAGGCGCAGTGTCATGCCGCGTCACCCCTGCGATGAGATTAAAGAACCATTGCGTAAAGCAATCCTGAAAC
AACTCGGTTTGAGTTAA

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 13224.95 Da        Isoelectric Point: 5.8684

>AT218991 WP_045844422.1 NZ_CP084647:447499-447867 [Yersinia ruckeri]
MNNHMTTSPTWGLKRDITPCLGARLVQEGTHLHFLSDRANIVGTFSPQTTQSLDVAFPALITKLESQLLSGALDPHRQQG
ITVRHGEFVCDGDTLGSHGYVYIAVYQELPLLLSEGGGPPDV

Download         Length: 369 bp

>AT218991 NZ_CP116152:c2397065-2396649 [Escherichia coli]
ATGCGTTATCCCGTCACTCTTACACCCGCGCCGGAAGGCGGTTATATGGTTTCTTTTGTGGATATCCCTGAAGCGTTGAC
GCAGGGCGAAACTGTCGCTGAAGCGATGGAAGCGGCAAAAGATGCTTTACTGACCGCATTTGATTTTTATTTTGAAGATA
ACGAGCTTATCCCTTTACCTTCGCCATTAAATAGTCATGATCACTTTATTGAAGTACCTTTGAGCGTCGCCTCTAAGGTA
TTGCTGTTAAATGCTTTTTTACAGTCAGAAATCACTCAGCAAGAGTTAGCCAGGCGAATTGGCAAACCTAAACAGGAGAT
TACTCGCCTATTTAACTTGCATCATGCGACAAAAATCGACGCCGTCCAGCTCGCGGCAAAGGCGCTTGGCAAAGAGTTAT
CGCTGGTGATGGTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References