218990

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) TsxAB/MqsA(antitoxin)
Location 540..1026 Replicon plasmid p17Y0159.3
Accession NZ_CP084646
Organism Yersinia ruckeri strain 17Y0159

Toxin (Protein)


Gene name TsxA Uniprot ID -
Locus tag LGL91_RS18130 Protein ID WP_115195446.1
Coordinates 540..800 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name TsxB Uniprot ID -
Locus tag LGL91_RS18135 Protein ID WP_115195447.1
Coordinates 790..1026 (+) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LGL91_RS18125 (LGL91_18185) 1..543 + 543 WP_115195445.1 hypothetical protein -
LGL91_RS18130 (LGL91_18190) 540..800 + 261 WP_115195446.1 hypothetical protein Toxin
LGL91_RS18135 (LGL91_18195) 790..1026 + 237 WP_115195447.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
LGL91_RS18140 (LGL91_18200) 1125..1304 + 180 WP_115195448.1 hypothetical protein -
LGL91_RS18335 1294..1419 + 126 WP_265099277.1 hypothetical protein -
LGL91_RS18145 (LGL91_18205) 2020..2523 + 504 WP_208780007.1 DNA distortion polypeptide 1 -
LGL91_RS18150 (LGL91_18210) 2527..3756 + 1230 WP_115195450.1 MobP1 family relaxase -
LGL91_RS18155 (LGL91_18215) 3833..4099 + 267 WP_115195451.1 LuxR C-terminal-related transcriptional regulator -
LGL91_RS18160 (LGL91_18220) 4110..4325 + 216 WP_228708726.1 EexN family lipoprotein -
LGL91_RS18165 (LGL91_18225) 4683..5309 + 627 WP_115195453.1 lytic transglycosylase domain-containing protein -
LGL91_RS18170 (LGL91_18230) 5322..5648 + 327 WP_228708727.1 TrbC/VirB2 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..28708 28708


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Antitoxin MqsA/HigA-2

(6-70)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10216.86 Da        Isoelectric Point: 9.6755

>T218990 WP_115195446.1 NZ_CP084646:540-800 [Yersinia ruckeri]
MRKNKGDITYYLEENAGVYHFVKKIKTRSKLMTEGKSKITKKMLSEFYFVENEFNLIDFTTNGLRVVDKEIIITMIKEIK
ESDRDN

Download         Length: 261 bp

>T218990 NZ_CP116152:2312526-2313848 [Escherichia coli]
ATGCCTAAACTTGTCACTTGGATGAACAACCAGCGGGTAGGCGAGTTAACGAAGTTAGCCAACGGCGCGCACACCTTTAA
GTATGCACCGGAGTGGTTAGCAAGCCGTTATGCCAGACCGTTGTCACTTTCGCTGCCATTGCAGAGGGGGAATATCACCT
CTGATGCCGTATTTAACTTCTTCGATAACCTGTTACCCGATAGCCCGATTGTACGTGACCGGATCGTTAAACGTTATCAT
GCCAAATCCAGACAACCGTTTGATTTATTGTCAGAAATAGGGCGAGACAGCGTTGGTGCCGTGACGTTAATACCCGAAGA
CGAAACCGTAACGCATCCGATAATGGCATGGGAAAAGCTTACTGAAGCCAGACTTGAAGAAGTATTAACGGCTTATAAAG
CAGATATCCCGCTAGGCATGATTAGAGAAGAAAATGACTTTCGCATCTCGGTTGCTGGCGCACAGGAGAAGACAGCACTG
CTCAGAATAGGCAATGACTGGTGCATTCCGAAAGGAATAACGCCGACGACGCACATCATTAAATTACCGATTGGCGAAAT
CAGGCAGCCCAATGCGACGCTCGATCTCAGCCAAAGCGTTGATAATGAGTATTACTGTCTGCTGCTGGCGAAAGAACTTG
GGTTGAATGTTCCGGACGCAGAAATCATTAAAGCGGGAAATGTGCGCGCGTTAGCGGTCGAACGTTTTGACAGGCGTTGG
AATGCTGAGCGAACGGTTTTACTTCGCTTGCCACAGGAGGATATGTGTCAGACATTCGGTTTACCTTCATCGGTGAAATA
TGAATCAGATGGAGGCCCAGGCATCGCGCGGATCATGGCTTTTTTGATGGGGTCCAGCGAGGCGCTGAAAGATCGCTATG
ATTTTATGAAATTCCAGGTCTTCCAGTGGTTGATTGGCGCAACGGACGGTCATGCAAAAAACTTCTCCGTATTTATTCAG
GCTGGCGGCAGTTATCGACTCACGCCATTTTACGACATCATTTCAGCATTTCCGGTCCTTGGCGGTACGGGAATACACAT
CAGCGATCTCAAACTGGCAATGGGGCTTAACGCATCCAAAGGCAAAAAAACGGCAATCGATAAAATTTATCCGCGACATT
TTTTGGCGACAGCAAAGGTGCTGAGATTCCCGGAAGTGCAGATGCATGAAATCCTGAGTGACTTTGCCAGAATGATTCCA
GCAGCACTGGATAACGTGAAGACTTCATTACCGACAGATTTTCCGGAGAACGTGGTGACGGCAGTTGAAAGCAATGTGTT
GAGGTTGCATGGACGGTTAAGCCGAGAATACGGTAGTAAGTGA

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 9058.47 Da        Isoelectric Point: 9.6558

>AT218990 WP_115195447.1 NZ_CP084646:790-1026 [Yersinia ruckeri]
VITDNTPENIKKLREKLGITQTECGKLFGVGLRTWQKKEEAKTHNRLSLSKGEFEYLLLMAGEHPDFVLEKRKKTEKE

Download         Length: 237 bp

>AT218990 NZ_CP116152:2312260-2312526 [Escherichia coli]
ATGATGAGCTTTCAGAAGATCTATAGCCCAACGCAATTGGCGAATGCAATGAAACTGGTTCGCCAGCAAAATGGCTGGAC
GCAGAGCGAGCTGGCGAAAAAAATTGGTATTAAGCAGGCGACGATTTCCAATTTCGAAAACAACCCTGACAATACCACGC
TCACGACATTTTTTAAGATTTTACAGTCGCTTGAACTCTCAATGACGCTATGCGACGCGAAAAATGCCTCGCCAGAATCA
ACAGAACAGCAAAATCTGGAGTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References