Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/ParE-RelB |
| Location | 463619..464153 | Replicon | chromosome |
| Accession | NZ_CP084643 | ||
| Organism | Yersinia ruckeri strain 17Y0159 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | A0A0T9LYG3 |
| Locus tag | LGL91_RS02125 | Protein ID | WP_038275268.1 |
| Coordinates | 463863..464153 (+) | Length | 97 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | - |
| Locus tag | LGL91_RS02120 | Protein ID | WP_234056963.1 |
| Coordinates | 463619..463873 (+) | Length | 85 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LGL91_RS02090 (LGL91_02105) | 458860..459954 | + | 1095 | WP_234056962.1 | LPS export ABC transporter permease LptF | - |
| LGL91_RS02095 (LGL91_02110) | 459954..461024 | + | 1071 | WP_038241732.1 | LPS export ABC transporter permease LptG | - |
| LGL91_RS02105 (LGL91_02120) | 461410..461733 | + | 324 | Protein_398 | Arm DNA-binding domain-containing protein | - |
| LGL91_RS02110 (LGL91_02125) | 461751..462898 | - | 1148 | Protein_399 | IS3 family transposase | - |
| LGL91_RS02115 (LGL91_02130) | 463071..463445 | + | 375 | Protein_400 | tyrosine-type recombinase/integrase | - |
| LGL91_RS02120 (LGL91_02135) | 463619..463873 | + | 255 | WP_234056963.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
| LGL91_RS02125 (LGL91_02140) | 463863..464153 | + | 291 | WP_038275268.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| LGL91_RS02130 (LGL91_02145) | 464417..464806 | + | 390 | WP_234056964.1 | restriction endonuclease subunit S | - |
| LGL91_RS02135 (LGL91_02150) | 464930..465505 | + | 576 | WP_234049239.1 | DarT ssDNA thymidine ADP-ribosyltransferase family protein | - |
| LGL91_RS02140 (LGL91_02155) | 465508..466164 | + | 657 | WP_096823271.1 | DUF4433 domain-containing protein | - |
| LGL91_RS02145 (LGL91_02160) | 466161..467228 | + | 1068 | WP_096823272.1 | macro domain-containing protein | - |
| LGL91_RS02150 (LGL91_02165) | 467249..467515 | + | 267 | Protein_407 | hypothetical protein | - |
| LGL91_RS02155 (LGL91_02170) | 467534..467932 | - | 399 | Protein_408 | integrase core domain-containing protein | - |
| LGL91_RS02160 (LGL91_02175) | 467931..468227 | + | 297 | Protein_409 | integrase core domain-containing protein | - |
| LGL91_RS02165 (LGL91_02180) | 468256..468376 | - | 121 | Protein_410 | transposase | - |
| LGL91_RS02170 (LGL91_02185) | 468369..468497 | - | 129 | Protein_411 | helix-turn-helix domain-containing protein | - |
| LGL91_RS02175 (LGL91_02190) | 468647..468877 | + | 231 | Protein_412 | DUF4942 domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 461410..467228 | 5818 | |
| - | flank | IS/Tn | - | - | 467979..468227 | 248 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 97 a.a. Molecular weight: 11494.42 Da Isoelectric Point: 9.9816
>T218974 WP_038275268.1 NZ_CP084643:463863-464153 [Yersinia ruckeri]
MTFNIDFDERALKEWHKLDKTIREQFKKKLRKLQENPYIESARLHGDLAGCFKIKLRASGFRLIYQVIDEEIVIWIVAVG
KREDEKAYDIAKKRIQ
MTFNIDFDERALKEWHKLDKTIREQFKKKLRKLQENPYIESARLHGDLAGCFKIKLRASGFRLIYQVIDEEIVIWIVAVG
KREDEKAYDIAKKRIQ
Download Length: 291 bp
>T218974 NZ_CP116145:3574948-3575232 [Escherichia coli]
ATGCAATTTACGGTATACCGCAGTCGCGGCAGGAACGCCGCGTTTCCCTTTGTTATTGATGTTACCAGCGACATTATTGG
TGAGATTAATCGCCGTATCGTTATTCCATTAACACCTATTGAACGATTTAGCCGTATTCGCCCACCAGAACGGCTTAACC
CAATCCTTTTACTGATAGACGGCAAAGAATATGTGCTCATGACGCATGAGACTGCAACTGTTCCAGTTAACGCGCTGGGA
ACGAAATTTTGCGATGCCAGCGCGCACCGAACGTTGATTAAATGA
ATGCAATTTACGGTATACCGCAGTCGCGGCAGGAACGCCGCGTTTCCCTTTGTTATTGATGTTACCAGCGACATTATTGG
TGAGATTAATCGCCGTATCGTTATTCCATTAACACCTATTGAACGATTTAGCCGTATTCGCCCACCAGAACGGCTTAACC
CAATCCTTTTACTGATAGACGGCAAAGAATATGTGCTCATGACGCATGAGACTGCAACTGTTCCAGTTAACGCGCTGGGA
ACGAAATTTTGCGATGCCAGCGCGCACCGAACGTTGATTAAATGA
Antitoxin
Download Length: 85 a.a. Molecular weight: 9650.09 Da Isoelectric Point: 5.1212
>AT218974 WP_234056963.1 NZ_CP084643:463619-463873 [Yersinia ruckeri]
MSTIQIRVDDELKKSAYQAFEKLNLSPSDALRLFLRYVAENEKLPFSEVSVMVSNQDVDADILAVVRERLKNPAKRIRVN
IDDL
MSTIQIRVDDELKKSAYQAFEKLNLSPSDALRLFLRYVAENEKLPFSEVSVMVSNQDVDADILAVVRERLKNPAKRIRVN
IDDL
Download Length: 255 bp
>AT218974 NZ_CP116145:3574712-3574945 [Escherichia coli]
ATGACTGCAAAACGTACCACACAAAGTGTGACCGTCACCGTCGACCGTGAGTTAGTCAATCGCGCTCGTGATGCAGGCTT
AAATATGAGCGCCACCCTTACGGTTGCGCTCAATGCTGAACTTAAAAAACATGCAGCAACACGTTGGCGTGAAGAGAACG
CAGAAGCTATCGCTGCGTTAAATCAATTGGCTGATGAAACCGGATGTTTCTCTGATGAGTACCGGAGCTTCTAG
ATGACTGCAAAACGTACCACACAAAGTGTGACCGTCACCGTCGACCGTGAGTTAGTCAATCGCGCTCGTGATGCAGGCTT
AAATATGAGCGCCACCCTTACGGTTGCGCTCAATGCTGAACTTAAAAAACATGCAGCAACACGTTGGCGTGAAGAGAACG
CAGAAGCTATCGCTGCGTTAAATCAATTGGCTGATGAAACCGGATGTTTCTCTGATGAGTACCGGAGCTTCTAG
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|