218972

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 3178906..3180626 Replicon chromosome
Accession NZ_CP084642
Organism Yersinia ruckeri strain 17Y0161

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag LGL90_RS14515 Protein ID WP_096823271.1
Coordinates 3179970..3180626 (-) Length 219 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag LGL90_RS14510 Protein ID WP_038245756.1
Coordinates 3178906..3179973 (-) Length 356 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LGL90_RS14460 (LGL90_14490) 3175132..3175305 - 174 Protein_2802 type IV toxin-antitoxin system YeeU family antitoxin -
LGL90_RS14465 (LGL90_14495) 3175331..3175456 - 126 Protein_2803 antirestriction protein -
LGL90_RS14470 (LGL90_14500) 3175824..3176774 - 951 WP_234049238.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
LGL90_RS14475 (LGL90_14505) 3176767..3177162 - 396 WP_038245317.1 DUF6088 family protein -
LGL90_RS14480 (LGL90_14510) 3177237..3177467 - 231 Protein_2806 DUF4942 domain-containing protein -
LGL90_RS14485 (LGL90_14515) 3177617..3177745 + 129 Protein_2807 helix-turn-helix domain-containing protein -
LGL90_RS14490 (LGL90_14520) 3177738..3177858 + 121 Protein_2808 transposase -
LGL90_RS14495 (LGL90_14525) 3177887..3178183 - 297 Protein_2809 integrase core domain-containing protein -
LGL90_RS14500 (LGL90_14530) 3178182..3178580 + 399 Protein_2810 integrase core domain-containing protein -
LGL90_RS14505 (LGL90_14535) 3178599..3178885 - 287 Protein_2811 hypothetical protein -
LGL90_RS14510 (LGL90_14540) 3178906..3179973 - 1068 WP_038245756.1 macro domain-containing protein Antitoxin
LGL90_RS14515 (LGL90_14545) 3179970..3180626 - 657 WP_096823271.1 DUF4433 domain-containing protein Toxin
LGL90_RS14520 (LGL90_14550) 3180629..3181204 - 576 WP_234049239.1 DarT ssDNA thymidine ADP-ribosyltransferase family protein -
LGL90_RS14525 (LGL90_14555) 3181328..3181717 - 390 WP_234049240.1 restriction endonuclease subunit S -
LGL90_RS14530 (LGL90_14560) 3181981..3182271 - 291 WP_038275268.1 type II toxin-antitoxin system RelE/ParE family toxin -
LGL90_RS14535 (LGL90_14565) 3182261..3182515 - 255 WP_005175264.1 type II toxin-antitoxin system RelB/DinJ family antitoxin -
LGL90_RS14545 (LGL90_14575) 3183904..3185088 - 1185 WP_234049241.1 integrase arm-type DNA-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 3173375..3182515 9140
- inside IScluster/Tn - - 3177887..3183841 5954


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(17-217)

Antitoxin

Macro domain

(18-129)


Sequences

Toxin        


Download         Length: 219 a.a.        Molecular weight: 25214.72 Da        Isoelectric Point: 6.6007

>T218972 WP_096823271.1 NZ_CP084642:c3180626-3179970 [Yersinia ruckeri]
VAYDYSTSLNPEKALIWRIVHRDNIPWILDNGLHCGNSPVQAEDWINIGNPELIDKRAGHLVPTGMRGTLHDYVPFYFTP
FSPMLMNIRSGRGGIKQRPNEEIVILVSSLRNMVAQNVSFVFTDSHAYYNLANYFTELDSLNQIDWPILQARDFRRDQDD
LAKFERYQAEALIWKHCPIALLGGMICYNDGVRLQLEQWLSQRNLSMPVHARAGWYFS

Download         Length: 657 bp

>T218972 NZ_CP116145:3382033-3382410 [Escherichia coli]
ATGAAAACATTACCCGACACGCATGTACGGGAGGTATCGTGCTGCCCGTCTCCAGTCACCATCTGGCAGACACTGCTCAC
CCGACTGCTGGACCAGCACTACGGCCTTACGCTGAATGACACACCGTTCGCTGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGTGATGCAGTGAACTTTCTCGTGGAAAAATACGCACTGGTACGTACCGACCTGCCGGGATTC
AGCGCCTGTACCCACTCTCAGTTAATAAACAGCATCGATATCCTCCGGGCTCGCCGGGCAACAGGCCTGATGATCCGCGA
CAATTACAGAACGGTAAATAACATTACCCTGGGGAAGCATCCGGAGGCGAAACGATGA

Antitoxin


Download         Length: 356 a.a.        Molecular weight: 40846.27 Da        Isoelectric Point: 6.6976

>AT218972 WP_038245756.1 NZ_CP084642:c3179973-3178906 [Yersinia ruckeri]
MITFTQGNLLDAPVEALVNTVNTVGVMGKGIALMFKERFPVNMKAYALACKHKQVMTGKMFITETGELMGPRWIVNFPTK
QHWRADSRMEWVEDGLQDLRRFLIKEKVQSIAIPPLGAGNGGLNWSDVRMRIESALGDLQDTEILIYEPTEKYQNVAKST
GVKKLTPARALIAELVRRYWVLGMECSLLEIQKLAWLLQRAIEQHQQEDVLKLRFEAHYYGPYAPNLNHLLNALDGTYLK
AEKRIPDTQPLDVIWFNDQEKEHINLWLNNEAKEWLPALEQVSQLIDGFESPFGLELLATVDWLLTRGKCQPTLDSVKEG
LHQWPAGERWASRKMKLFDDKNLQFAINRVMEFHC

Download         Length: 1068 bp

>AT218972 NZ_CP116145:3381575-3381943 [Escherichia coli]
GTGTCAGACACACTTTCCGGGACAACGCATCCCGATGACAATGACGACCATCCCTGGTGGGGACTACCCTGCACAGTGAC
GCCCTGTTTCGGCGCCCGTCTGGTGCAGGAGGGTAACCGGTTGCATTACCTTGCCGACCGTGCCGGTATCAGAGGCCGGT
TCAGAGATGCGGATGCGTACCCTCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGAAATTAATGCTCACCAGTGGT
GAACTGAATCCCCGCCATCAGCATACCGTGACACTGTATGCGAAGGGGCTGACCTGTGAAGCCGACACCCTCGGCTCCTG
TGGTTACGTTTATCTGGCTGTTTATCCGACACCTGAAACGAAAAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References