Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3057738..3058407 Replicon chromosome
Accession NZ_CP084637
Organism Yersinia ruckeri strain 17Y0412

Toxin (Protein)


Gene name cptA Uniprot ID A0A380QS17
Locus tag LGL85_RS14335 Protein ID WP_038241020.1
Coordinates 3057738..3058160 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag LGL85_RS14340 Protein ID WP_004719196.1
Coordinates 3058141..3058407 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LGL85_RS14315 (LGL85_14355) 3053577..3055310 - 1734 WP_038276198.1 single-stranded-DNA-specific exonuclease RecJ -
LGL85_RS14320 (LGL85_14360) 3055317..3056033 - 717 WP_004719192.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
LGL85_RS14325 (LGL85_14365) 3056065..3056964 - 900 WP_004719193.1 site-specific tyrosine recombinase XerD -
LGL85_RS14330 (LGL85_14370) 3057072..3057590 + 519 WP_038241022.1 flavodoxin FldB -
LGL85_RS14335 (LGL85_14375) 3057738..3058160 - 423 WP_038241020.1 protein YgfX Toxin
LGL85_RS14340 (LGL85_14380) 3058141..3058407 - 267 WP_004719196.1 FAD assembly factor SdhE Antitoxin
LGL85_RS14345 (LGL85_14385) 3058701..3059693 + 993 WP_096823598.1 tRNA-modifying protein YgfZ -
LGL85_RS14350 (LGL85_14390) 3059832..3060497 - 666 WP_175537887.1 hemolysin III family protein -
LGL85_RS14355 (LGL85_14395) 3060814..3061070 + 257 Protein_2787 HD domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 16451.41 Da        Isoelectric Point: 11.1478

>T218930 WP_038241020.1 NZ_CP084637:c3058160-3057738 [Yersinia ruckeri]
VAQWRCDLRVSWRTQLFSLLVHGVLVLLTLVVPWPDGFTPLWLILLTLVVFECIRSQKNITSRQGEIRLKAGNLLIWKWQ
EWTLVRPPWITRYGVLLSLQGAGSRRRKRIWLASDSMSEEKWRELCLILRHTFDSAAGRE

Download         Length: 423 bp

>T218930 NZ_CP116136:254117-254224 [Escherichia coli]
ATGACGCTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGCATGAT
CGTGAACTGGCTGAATAAGCGGAAGTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10532.09 Da        Isoelectric Point: 6.7185

>AT218930 WP_004719196.1 NZ_CP084637:c3058407-3058141 [Yersinia ruckeri]
MEIDNKARIHWACRRGMRELDISIMPFFEHEYDTLNDNDKRVFIRLLTSDDPDLFNWLMNHGEPQDSELKRMVKLIQTRN
KARGPVAM

Download         Length: 267 bp

>AT218930 NZ_CP116136:c254059-254005 [Escherichia coli]
CAAGAATGGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A380QS17

Antitoxin

Source ID Structure

References