Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbE-relB/ParE-YafN
Location 5163491..5163986 Replicon chromosome
Accession NZ_CP084625
Organism Pseudomonas lalkuanensis strain ACYW.190

Toxin (Protein)


Gene name stbE Uniprot ID -
Locus tag LF844_RS23965 Protein ID WP_151137493.1
Coordinates 5163726..5163986 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LF844_RS23960 Protein ID WP_226282818.1
Coordinates 5163491..5163736 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LF844_RS23930 (LF844_23930) 5158878..5159576 + 699 WP_151137481.1 urea ABC transporter ATP-binding subunit UrtE -
LF844_RS23935 (LF844_23935) 5159599..5160438 + 840 WP_226282812.1 urease accessory protein UreD -
LF844_RS23940 (LF844_23940) 5160438..5160740 + 303 WP_226282814.1 urease subunit gamma -
LF844_RS23945 (LF844_23945) 5160819..5161313 + 495 WP_226282816.1 GNAT family N-acetyltransferase -
LF844_RS23950 (LF844_23950) 5161318..5161623 + 306 WP_151137487.1 urease subunit beta -
LF844_RS23955 (LF844_23955) 5161701..5163401 + 1701 WP_151137489.1 urease subunit alpha -
LF844_RS23960 (LF844_23960) 5163491..5163736 + 246 WP_226282818.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
LF844_RS23965 (LF844_23965) 5163726..5163986 + 261 WP_151137493.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LF844_RS23970 (LF844_23970) 5164029..5164295 - 267 WP_151137494.1 DksA/TraR family C4-type zinc finger protein -
LF844_RS23975 (LF844_23975) 5164393..5165259 - 867 WP_226282820.1 oxaloacetate decarboxylase -
LF844_RS23980 (LF844_23980) 5165447..5165893 + 447 WP_151137498.1 YqaA family protein -
LF844_RS23985 (LF844_23985) 5166115..5166468 + 354 WP_226282822.1 DUF6152 family protein -
LF844_RS23990 (LF844_23990) 5166476..5166958 + 483 WP_151137502.1 hypothetical protein -
LF844_RS23995 (LF844_23995) 5167048..5167317 - 270 WP_151137504.1 PsiF family protein -
LF844_RS24000 (LF844_24000) 5167436..5168701 + 1266 WP_226282823.1 Hsp70 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-81)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(10-66)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10037.77 Da        Isoelectric Point: 11.1724

>T218908 WP_151137493.1 NZ_CP084625:5163726-5163986 [Pseudomonas lalkuanensis]
MTYELEFLPSARKEWRKLGDTVREQFRKKLKERLQRQLIQGDALHGMPERFKIKLRTAGYRLVDRVEDQRITVVVIGVGK
RAGGAV

Download         Length: 261 bp

>T218908 NZ_CP116123:2874344-2874451 [Escherichia coli]
ATGACGCTCACGCAGTTTGCCATGACTTTCTGGCACGACTTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8507.80 Da        Isoelectric Point: 6.4571

>AT218908 WP_226282818.1 NZ_CP084625:5163491-5163736 [Pseudomonas lalkuanensis]
MQSVLANGAVSVSALKKNPSAVVSGAKGAPVAVLNHNKVMAYMVSAETFEALLENLDDQALAEIVRSRAHEKGMKVSLDD
L

Download         Length: 246 bp

>AT218908 NZ_CP116123:c2874294-2874231 [Escherichia coli]
TCTGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTATACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References