Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /BrnT(toxin)
Location 111003..111498 Replicon chromosome
Accession NZ_CP084578
Organism Sulfurimonas sp. SWIR-19

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag LCX93_RS00510 Protein ID WP_226067042.1
Coordinates 111003..111263 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag LCX93_RS00515 Protein ID WP_226067044.1
Coordinates 111253..111498 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LCX93_RS00490 (LCX93_00490) 106699..108090 - 1392 WP_226067034.1 cobyric acid synthase -
LCX93_RS00495 (LCX93_00495) 108094..108525 - 432 WP_226067036.1 thioredoxin fold domain-containing protein -
LCX93_RS00500 (LCX93_00500) 108509..109531 - 1023 WP_226067038.1 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme -
LCX93_RS00505 (LCX93_00505) 109843..110742 + 900 WP_226067040.1 hypothetical protein -
LCX93_RS00510 (LCX93_00510) 111003..111263 + 261 WP_226067042.1 BrnT family toxin Toxin
LCX93_RS00515 (LCX93_00515) 111253..111498 + 246 WP_226067044.1 CopG family antitoxin Antitoxin
LCX93_RS00520 (LCX93_00520) 111645..111944 + 300 WP_226067046.1 BrnT family toxin -
LCX93_RS00525 (LCX93_00525) 111937..112203 + 267 WP_226067048.1 hypothetical protein -
LCX93_RS00530 (LCX93_00530) 112956..113327 + 372 WP_226067050.1 helix-turn-helix domain-containing protein -
LCX93_RS00535 (LCX93_00535) 113379..113600 + 222 WP_226067052.1 excalibur calcium-binding domain-containing protein -
LCX93_RS00540 (LCX93_00540) 113642..114442 - 801 WP_226067054.1 phosphotransferase -
LCX93_RS00545 (LCX93_00545) 114443..114868 - 426 WP_226067055.1 hypothetical protein -
LCX93_RS00550 (LCX93_00550) 114882..115850 - 969 WP_226067057.1 iron ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(5-80)

Antitoxin

CopG antitoxin

(14-70)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10349.85 Da        Isoelectric Point: 9.2961

>T218871 WP_226067042.1 NZ_CP084578:111003-111263 [Sulfurimonas sp. SWIR-19]
MKFEYDIKKSLSNKQKHGIDFEEAKLLWNDDNMVEIRTSYEDEERFITIGKITAKIYAVVTTYRKENIRIISARRARKKE
IEIYES

Download         Length: 261 bp

>T218871 NZ_CP116115:c613407-613066 [Escherichia coli]
ATGACTGACACGCATTCTATTGCACAACCGTTCGAAGCAGAAGTCTCCCCGGCAAATAACCGTCAATTAACCGTGAGTTA
TGCGAGTCGCTACCCGGATTACAGCCGTATTCCCGCCATCACCCTGAAAGGTCAGTGGCTGGAAGCCGCCGGTTTTGCCA
CCGGCACTGCGGTAGATGTCAAAGTAATGGAAGGCTGTATTGTCCTCACCGCCCAACCACCCGCCGCCGCCGAGAGCGAA
CTGATGCAGTCGCTGCGCCAGGTGTGCAAGCTGTCGGCGCGTAAACAAAGGCAGGTGCAGGAGTTTATTGGGGTGATTGC
GGGTAAACAGAAAGTCGCCTGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9622.12 Da        Isoelectric Point: 5.1603

>AT218871 WP_226067044.1 NZ_CP084578:111253-111498 [Sulfurimonas sp. SWIR-19]
MKAEEFDKIFDDNEEDIIDYLDMSTIRRPNLEPKRINIDFPAWMVKKLDEEAKHIGVSRQAIIKTWLADKIMQIEHHKVA
V

Download         Length: 246 bp

>AT218871 NZ_CP116115:613402-613478 [Escherichia coli]
AGTCATAACTGCTATTCCCTATAAATAGTGATTGTGATTAGCGGTGCGGGTGTGTTGGCGCACATCCGCACCGCGCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References