Detailed information of TA system TA218869

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE-Phd
• Location: 4455420..4455985
• Replicon: chromosome
• Accession: NZ_CP084560
• Organism: Arthrobacter sp. FW306-2-2C-D06B

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: LFT47_RS20830
• Protein ID: WP_272909600.1
• Coordinates: 4455692..4455985 (+)
• Length: 98 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: LFT47_RS20825
• Protein ID: WP_236813754.1
• Coordinates: 4455420..4455695 (+)
• Length: 92 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LFT47_RS20810 (LFT47_20870)	4451268..4452212	-	945	WP_236813748.1	ABC transporter substrate-binding protein	-
LFT47_RS20815 (LFT47_20875)	4452209..4453504	-	1296	WP_236813750.1	alpha-hydroxy acid oxidase	-
LFT47_RS20820 (LFT47_20880)	4453631..4455295	+	1665	WP_236813752.1	helix-turn-helix domain-containing protein	-
LFT47_RS20825 (LFT47_20885)	4455420..4455695	+	276	WP_236813754.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
LFT47_RS20830 (LFT47_20890)	4455692..4455985	+	294	WP_272909600.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
LFT47_RS20835 (LFT47_20895)	4456004..4459480	-	3477	WP_236813756.1	fibronectin type III domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (15-94)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-71)

Sequences

Toxin

Protein

• Length: 98 a.a.
• Molecular weight: 10912.47 Da
• Isoelectric Point: 10.0859

>T218869 WP_272909600.1 NZ_CP084560:4455692-4455985 [Arthrobacter sp. FW306-2-2C-D06B]
VTGPEPTGPAAWNVQVTSPALRGFRRLPEKAAAAIVEFVTGALAENPHRLSKPLTNELLGLRTARRGDYRVLFTLDIEEH
TLYVHRIEHRSDVYKPR

Nucleotide

• Length: 294 bp

>T218869 NZ_CP116115:c316862-316488 [Escherichia coli]
ATGAAAACATTACCCGATACACACGTACGGGAGGCATCGAGCTGCCCGTCTCCCGTCACCATCTGGCAGACTCTGCTCTC
CCGACTACTGGGCCAGCATTACGGCCTTACACTGAATGACACACCGTTCGCCGATGAACGTGTGATTGAGCAGCATATTG
AAGCTGGCATTTCACTGTGTGATGCGGTGAATTTTCTCGTGGAAAAATACGCGCTGGTGCGTACCGACCAGCCGGGATTC
AGCACTTGTCCCCGCTCTCAGTTAATAAACAGTATTGATATCCTCCGGGCTCGCCGGGCGACCGGCCTGATGACCCGCGA
CAATTACAGAACGGTAAATAACATTACCCTGGGTAAGCATCCGGAGAAACGATGA

Antitoxin

Protein

• Length: 92 a.a.
• Molecular weight: 10142.28 Da
• Isoelectric Point: 4.6847

>AT218869 WP_236813754.1 NZ_CP084560:4455420-4455695 [Arthrobacter sp. FW306-2-2C-D06B]
MRTVPLSEAKDKLSALVEEADTTHEIIQITRHGHPSAVLMSADDLESLQETIHWLSQPGIREDLDQARRDIAEGNTTSGA
DLRREFGLPPR

Nucleotide

• Length: 276 bp

>AT218869 NZ_CP116115:c317320-316952 [Escherichia coli]
GTGTCAGACAAACTCTCCGGGATAACTCATCCCGACGACAATCACGACCGCCCCTGGTGGGGGCTTCCCTGCACAGTGAG
GCCCTGTTTTGGTGCCCGTCTGGTGCAGGAGGGTAACCGCCTGCATTACCTTGCCGACCGCGCCGGTATCAGAGGCCGCT
TCAGCGACGCAGATGCATACCATCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGGAGCTCATGCTCACCAGCGGT
GAACTGAATCCCCGCCATCAGCATACCGTCACGCTGTATGCGAAAGGTCTGACCTGCAAAGCTGACACCCTCGGTAGCGG
TGGTTACGTTTATCTGGCTGTTTATCCGACGCCCGAAACGAAAAAGTAA