Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 1414959..1415479 Replicon chromosome
Accession NZ_CP084560
Organism Arthrobacter sp. FW306-2-2C-D06B

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LFT47_RS06675 Protein ID WP_236816423.1
Coordinates 1414959..1415216 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LFT47_RS06680 Protein ID WP_236816425.1
Coordinates 1415213..1415479 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LFT47_RS06660 (LFT47_06685) 1411902..1412702 - 801 WP_236816417.1 purine-nucleoside phosphorylase -
LFT47_RS06665 (LFT47_06690) 1412848..1414263 + 1416 WP_236816419.1 NAD(P)H-quinone dehydrogenase -
LFT47_RS06670 (LFT47_06695) 1414281..1414490 - 210 WP_236816421.1 hypothetical protein -
LFT47_RS06675 (LFT47_06700) 1414959..1415216 - 258 WP_236816423.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LFT47_RS06680 (LFT47_06705) 1415213..1415479 - 267 WP_236816425.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
LFT47_RS06685 (LFT47_06710) 1415573..1416781 - 1209 WP_236810701.1 IS110 family transposase -
LFT47_RS06690 (LFT47_06715) 1417050..1418828 + 1779 WP_236816427.1 HNH endonuclease signature motif containing protein -
LFT47_RS06695 (LFT47_06720) 1418870..1419262 + 393 WP_236816429.1 DUF4440 domain-containing protein -
LFT47_RS06700 (LFT47_06725) 1419422..1419895 + 474 WP_236816431.1 tyrosine-protein phosphatase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(8-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-62)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9939.64 Da        Isoelectric Point: 11.7454

>T218868 WP_236816423.1 NZ_CP084560:c1415216-1414959 [Arthrobacter sp. FW306-2-2C-D06B]
VNYNITVLPAALRQLRKLPPEGRRRVQAAIELLAETPRPPGAKKLAGRLEWRVRTRDYRVLYRIDDGRLVIVVVQAGHRR
EIYRE

Download         Length: 258 bp

>T218868 NZ_CP116115:305352-305525 [Escherichia coli]
ATGGCACTATTCTCTAAAATATTAATTTTTTATGTGATTGGTGTGAACATATCCTTTGTCATTATCTGGTTTATCTCACA
TGAGAAAACACATATTCGTTTACTTAGTGCATTTCTGGTCGGAATAACCTGGCCAATGAGTCTTCCTGTGGCATTACTTT
TTTCTCTCTTTTAG

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10051.30 Da        Isoelectric Point: 4.3165

>AT218868 WP_236816425.1 NZ_CP084560:c1415479-1415213 [Arthrobacter sp. FW306-2-2C-D06B]
MTDIAITEARNHLATIVDTAHREREPVFLTRRGIRVAAVIDSAELERLREAAEELEDIRAVDLAWEEMEQTGQTPIPWED
VKRDLGLT

Download         Length: 267 bp

>AT218868 NZ_CP116115:305028-305324 [Escherichia coli]
ATGGAAGGTAAAAACAAGTTCAATACTTATGTTGTTTCTTTTGATTATCCATCATCTTATTCCTCAGTGTTCTTAAGGTT
AAGATCATTGATGTATGATATGAATTTCTCCTCTATCGTGGCTGATGAATATGGGATACCACGACAACTGAATGAAAACT
CCTTCGCAATAACGACATCGTTAGCCGCAAGTGAAATCGAAGATTTAATCAGGCTCAAATGCTTAGACTTACCGGATATT
GATTTTGACCTCAGCATTATGACAGTTGATGACTATTTCCGTCAGTTTTACAAGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References