Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2184203..2184371 Replicon chromosome
Accession NZ_CP084542
Organism Klebsiella michiganensis strain YL9

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2184261..2184364 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2184203..2184371 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LD277_RS10440 (LD277_10450) 2179330..2181390 + 2061 WP_014229840.1 oligopeptidase B -
LD277_RS10445 (LD277_10455) 2181397..2182056 - 660 WP_014229839.1 exodeoxyribonuclease X -
LD277_RS10450 (LD277_10460) 2182135..2182365 - 231 WP_004103351.1 DNA polymerase III subunit theta -
LD277_RS10455 (LD277_10465) 2182501..2182875 + 375 WP_014229838.1 CopC domain-containing protein YobA -
LD277_RS10460 (LD277_10470) 2182880..2183749 + 870 WP_014229837.1 copper homeostasis membrane protein CopD -
LD277_RS10465 (LD277_10475) 2183766..2184104 + 339 WP_004103344.1 YebY family protein -
- 2184203..2184371 - 169 - - Antitoxin
- 2184261..2184364 + 104 - - Toxin
LD277_RS10470 (LD277_10480) 2184489..2185448 - 960 WP_014229836.1 spore coat protein U domain-containing protein -
LD277_RS10475 (LD277_10485) 2185463..2187793 - 2331 WP_014838820.1 fimbria/pilus outer membrane usher protein -
LD277_RS10480 (LD277_10490) 2187796..2188560 - 765 WP_014229834.1 fimbria/pilus periplasmic chaperone -
LD277_RS10485 (LD277_10495) 2188579..2189097 - 519 WP_004852079.1 spore coat U domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T218854 NZ_CP084542:2184261-2184364 [Klebsiella michiganensis]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 169 bp

>AT218854 NZ_CP084542:c2184371-2184203 [Klebsiella michiganensis]
AACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCCTTATAAGAATAGTTTACCGTGTCAGGTTTTCCAGTCCGCGACAAAAGTG
GACGAATAA

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References