Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | yjhX-yjhQ/YjhX-GNAT |
Location | 2224683..2225497 | Replicon | chromosome |
Accession | NZ_CP084529 | ||
Organism | Escherichia coli strain Origami2-DE3 |
Toxin (Protein)
Gene name | yjhX | Uniprot ID | S1PA82 |
Locus tag | LFW28_RS10590 | Protein ID | WP_001054376.1 |
Coordinates | 2224683..2224940 (+) | Length | 86 a.a. |
Antitoxin (Protein)
Gene name | yjhQ | Uniprot ID | U9Z4B8 |
Locus tag | LFW28_RS10595 | Protein ID | WP_001309181.1 |
Coordinates | 2224952..2225497 (+) | Length | 182 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
LFW28_RS10565 (2219971) | 2219971..2221077 | + | 1107 | WP_001309184.1 | N-acetylneuraminate epimerase | - |
LFW28_RS10570 (2221142) | 2221142..2222122 | + | 981 | WP_000991438.1 | 9-O-acetyl-N-acetylneuraminic acid deacetylase | - |
LFW28_RS10575 (2222232) | 2222232..2222437 | + | 206 | Protein_2081 | HNH endonuclease | - |
LFW28_RS10580 (2222705) | 2222705..2223945 | - | 1241 | Protein_2082 | helicase YjhR | - |
LFW28_RS10585 (2224061) | 2224061..2224192 | + | 132 | WP_001309182.1 | hypothetical protein | - |
LFW28_RS10590 (2224683) | 2224683..2224940 | + | 258 | WP_001054376.1 | YjhX family toxin | Toxin |
LFW28_RS10595 (2224952) | 2224952..2225497 | + | 546 | WP_001309181.1 | N-acetyltransferase | Antitoxin |
LFW28_RS10600 (2225553) | 2225553..2226299 | + | 747 | WP_000354251.1 | class I SAM-dependent methyltransferase | - |
LFW28_RS10605 (2226468) | 2226468..2226686 | + | 219 | Protein_2087 | hypothetical protein | - |
LFW28_RS10610 (2226724) | 2226724..2226840 | + | 117 | Protein_2088 | VOC family protein | - |
LFW28_RS10615 (2227085) | 2227085..2228206 | + | 1122 | WP_000010829.1 | M42 family metallopeptidase | - |
LFW28_RS10620 (2228203) | 2228203..2228481 | + | 279 | WP_000722973.1 | PTS sugar transporter subunit IIB SgcB | - |
LFW28_RS10625 (2228493) | 2228493..2229806 | + | 1314 | WP_000460843.1 | PTS sugar transporter subunit IIC SgcC | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Genomic island | - | fimI / fimA / fimE / fimB | 2214469..2233721 | 19252 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 86 a.a. Molecular weight: 9734.29 Da Isoelectric Point: 11.0090
>T218800 WP_001054376.1 NZ_CP084529:2224683-2224940 [Escherichia coli]
MNLSRQEQHTLHVLAKGRRIAHVRDSSGRVTSVECYSREGLLLTDCTLAVFKKLKTKKLIKSVNGQPYRINTTELNKVRA
QLDNR
MNLSRQEQHTLHVLAKGRRIAHVRDSSGRVTSVECYSREGLLLTDCTLAVFKKLKTKKLIKSVNGQPYRINTTELNKVRA
QLDNR
Download Length: 258 bp
>T218800 NZ_CP116103:c692165-692013 [Escherichia coli]
ATGAAGCAGCATAAGGCGATGATTGTCGCCCTGATCGTCATCTGTATCACCGCCGTAGTGGCGGCGCTGGTAACGAGAAA
AGACCTCTGTGAGGTTCACATCCGAACTGGCCAGACGGAGGTTGCTGTTTTCACGGCTTACGAATCCGAGTAA
ATGAAGCAGCATAAGGCGATGATTGTCGCCCTGATCGTCATCTGTATCACCGCCGTAGTGGCGGCGCTGGTAACGAGAAA
AGACCTCTGTGAGGTTCACATCCGAACTGGCCAGACGGAGGTTGCTGTTTTCACGGCTTACGAATCCGAGTAA
Antitoxin
Download Length: 182 a.a. Molecular weight: 19956.90 Da Isoelectric Point: 6.3277
>AT218800 WP_001309181.1 NZ_CP084529:2224952-2225497 [Escherichia coli]
MTVHHFTFHITDKSDASDIREVETRAFGFSKEADLVASLLEDESARPALSLLARYEGKAVGHILFTRATFKGEMDSPLMH
ILAPLAVIPEYQGMGVGGRLIRTGIEHLRLMGCQTVFVLGHATYYPRHGFEPCAGDKGYPAPYPIPEEHKACWMMQSLTA
QPMTLTGHIRCADPDETGALT
MTVHHFTFHITDKSDASDIREVETRAFGFSKEADLVASLLEDESARPALSLLARYEGKAVGHILFTRATFKGEMDSPLMH
ILAPLAVIPEYQGMGVGGRLIRTGIEHLRLMGCQTVFVLGHATYYPRHGFEPCAGDKGYPAPYPIPEEHKACWMMQSLTA
QPMTLTGHIRCADPDETGALT
Download Length: 546 bp
>AT218800 NZ_CP116103:692214-692271 [Escherichia coli]
GTTCTGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA
GTTCTGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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