Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1939776..1939921 Replicon chromosome
Accession NZ_CP084502
Organism Klebsiella pneumoniae strain MI01_K

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1939812..1939914 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1939776..1939921 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KRU50_RS09345 1934906..1936966 + 2061 WP_048289976.1 oligopeptidase B -
KRU50_RS09350 1936970..1937629 - 660 WP_002911407.1 exodeoxyribonuclease X -
KRU50_RS09355 1937708..1937938 - 231 WP_002911406.1 DNA polymerase III subunit theta -
KRU50_RS09360 1938051..1938425 + 375 WP_004151448.1 CopC domain-containing protein YobA -
KRU50_RS09365 1938429..1939298 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
KRU50_RS09370 1939315..1939653 + 339 WP_016529031.1 YebY family protein -
- 1939776..1939921 - 146 - - Antitoxin
- 1939812..1939914 + 103 - - Toxin
KRU50_RS09375 1940288..1940431 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
KRU50_RS09380 1940536..1941504 - 969 WP_004151446.1 VirK/YbjX family protein -
KRU50_RS09385 1941661..1942314 + 654 WP_020802220.1 protein-serine/threonine phosphatase -
KRU50_RS09390 1942311..1942502 - 192 WP_002911395.1 YebW family protein -
KRU50_RS09395 1942600..1942839 - 240 WP_002911393.1 YebV family protein -
KRU50_RS09400 1942955..1944388 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T218725 NZ_CP084502:1939812-1939914 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT218725 NZ_CP084502:c1939921-1939776 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References