Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2006686..2006831 Replicon chromosome
Accession NZ_CP084497
Organism Klebsiella pneumoniae strain 1632

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2006722..2006824 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2006686..2006831 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LDL62_RS09850 (LDL62_09850) 2001816..2003876 + 2061 WP_004151449.1 oligopeptidase B -
LDL62_RS09855 (LDL62_09855) 2003880..2004539 - 660 WP_002911407.1 exodeoxyribonuclease X -
LDL62_RS09860 (LDL62_09860) 2004618..2004848 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LDL62_RS09865 (LDL62_09865) 2004961..2005335 + 375 WP_004151448.1 CopC domain-containing protein YobA -
LDL62_RS09870 (LDL62_09870) 2005339..2006208 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
LDL62_RS09875 (LDL62_09875) 2006225..2006563 + 339 WP_002911404.1 YebY family protein -
- 2006686..2006831 - 146 - - Antitoxin
- 2006722..2006824 + 103 - - Toxin
LDL62_RS09880 (LDL62_09880) 2007199..2007342 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LDL62_RS09885 (LDL62_09885) 2007447..2008415 - 969 WP_004151446.1 VirK/YbjX family protein -
LDL62_RS09890 (LDL62_09890) 2008572..2009225 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
LDL62_RS09895 (LDL62_09895) 2009222..2009413 - 192 WP_002911395.1 YebW family protein -
LDL62_RS09900 (LDL62_09900) 2009511..2009750 - 240 WP_002911393.1 YebV family protein -
LDL62_RS09905 (LDL62_09905) 2009866..2011299 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T218699 NZ_CP084497:2006722-2006824 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT218699 NZ_CP084497:c2006831-2006686 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References