Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2022498..2022643 | Replicon | chromosome |
| Accession | NZ_CP084492 | ||
| Organism | Klebsiella pneumoniae strain 1864 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2022534..2022636 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2022498..2022643 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LDL64_RS09945 (LDL64_09945) | 2017628..2019688 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| LDL64_RS09950 (LDL64_09950) | 2019692..2020351 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| LDL64_RS09955 (LDL64_09955) | 2020430..2020660 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| LDL64_RS09960 (LDL64_09960) | 2020773..2021147 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| LDL64_RS09965 (LDL64_09965) | 2021151..2022020 | + | 870 | WP_062955019.1 | copper homeostasis membrane protein CopD | - |
| LDL64_RS09970 (LDL64_09970) | 2022037..2022375 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 2022498..2022643 | - | 146 | - | - | Antitoxin |
| - | 2022534..2022636 | + | 103 | - | - | Toxin |
| LDL64_RS09975 (LDL64_09975) | 2023011..2023154 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| LDL64_RS09980 (LDL64_09980) | 2023259..2024227 | - | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| LDL64_RS09985 (LDL64_09985) | 2024384..2025037 | + | 654 | WP_004180432.1 | protein-serine/threonine phosphatase | - |
| LDL64_RS09990 (LDL64_09990) | 2025034..2025225 | - | 192 | WP_002911395.1 | YebW family protein | - |
| LDL64_RS09995 (LDL64_09995) | 2025323..2025562 | - | 240 | WP_002911393.1 | YebV family protein | - |
| LDL64_RS10000 (LDL64_10000) | 2025678..2027111 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T218670 NZ_CP084492:2022534-2022636 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT218670 NZ_CP084492:c2022643-2022498 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
