Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | /Xre(antitoxin) |
| Location | 3540724..3541982 | Replicon | chromosome |
| Accession | NZ_CP084484 | ||
| Organism | Pseudomonas sp. PS1(2021) | ||
Toxin (Protein)
| Gene name | - | Uniprot ID | - |
| Locus tag | LE197_RS16920 | Protein ID | WP_023109087.1 |
| Coordinates | 3540724..3541479 (-) | Length | 252 a.a. |
Antitoxin (Protein)
| Gene name | - | Uniprot ID | V6AJU7 |
| Locus tag | LE197_RS16925 | Protein ID | WP_003086329.1 |
| Coordinates | 3541614..3541982 (-) | Length | 123 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LE197_RS16910 (LE197_16910) | 3535896..3538439 | + | 2544 | WP_003123188.1 | acyl-homoserine-lactone acylase QuiP | - |
| LE197_RS16915 (LE197_16915) | 3538594..3539955 | - | 1362 | WP_003081943.1 | DNA recombination protein RmuC | - |
| LE197_RS16920 (LE197_16920) | 3540724..3541479 | - | 756 | WP_023109087.1 | RES family NAD+ phosphorylase | Toxin |
| LE197_RS16925 (LE197_16925) | 3541614..3541982 | - | 369 | WP_003086329.1 | DUF2384 domain-containing protein | Antitoxin |
| LE197_RS16930 (LE197_16930) | 3542055..3543341 | - | 1287 | WP_003163134.1 | FAD-binding oxidoreductase | - |
| LE197_RS16935 (LE197_16935) | 3543397..3544986 | - | 1590 | WP_003125055.1 | aldehyde dehydrogenase family protein | - |
| LE197_RS16940 (LE197_16940) | 3545065..3545541 | + | 477 | WP_023109088.1 | hypothetical protein | - |
| LE197_RS16945 (LE197_16945) | 3545544..3545819 | - | 276 | WP_169057979.1 | zinc ribbon domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 252 a.a. Molecular weight: 28264.40 Da Isoelectric Point: 7.7294
>T218658 WP_023109087.1 NZ_CP084484:c3541479-3540724 [Pseudomonas sp. PS1(2021)]
VSEIWRQCKGERHIRPLQGRLVRLVESQEQVATLQLVDTLEEQALLEELLESSKPPVPADAEPLHYLLKTPFRYPPLRWG
SRFGRRHEPSLFYAALKLETAMAESAYYRCVLWSGMAVPPPSGRILSEHASFEAGWKVERGIRLQAPPFSDHEAALTDIA
DYRAPQELGTAMRSAGVQAFEYRSARCPERGCNVALFTPAAFTEKRPRNLTPWLCETTAGYVAFKPAHVPGSPKIFSWEL
FLVDGKLPHPA
VSEIWRQCKGERHIRPLQGRLVRLVESQEQVATLQLVDTLEEQALLEELLESSKPPVPADAEPLHYLLKTPFRYPPLRWG
SRFGRRHEPSLFYAALKLETAMAESAYYRCVLWSGMAVPPPSGRILSEHASFEAGWKVERGIRLQAPPFSDHEAALTDIA
DYRAPQELGTAMRSAGVQAFEYRSARCPERGCNVALFTPAAFTEKRPRNLTPWLCETTAGYVAFKPAHVPGSPKIFSWEL
FLVDGKLPHPA
Download Length: 756 bp
>T218658 NZ_CP116071:c2820275-2820120 [Escherichia coli]
ATGAAGCAGCAAAAGGCGATGTTAATCGCCCTGATCGTCATCTGTTTAACCGTCATAGTGACGGCACTGGTAACGAGGAA
AGACCTCTGCGAGGTACGAATCCGAACCGGCCAGACGGAGGTCGCTGTCTTCACAGCTTACGAACCTGAGGAGTAA
ATGAAGCAGCAAAAGGCGATGTTAATCGCCCTGATCGTCATCTGTTTAACCGTCATAGTGACGGCACTGGTAACGAGGAA
AGACCTCTGCGAGGTACGAATCCGAACCGGCCAGACGGAGGTCGCTGTCTTCACAGCTTACGAACCTGAGGAGTAA
Antitoxin
Download Length: 123 a.a. Molecular weight: 13367.63 Da Isoelectric Point: 9.9874
>AT218658 WP_003086329.1 NZ_CP084484:c3541982-3541614 [Pseudomonas sp. PS1(2021)]
MSALIKERPSADAVLAKAVLAAREQLGLTQLELAGIVGVDRSAISRWKTQGLRVDSKTGELALLLVRVYRALYALFGGQQ
EDMRHFLRTPNHHLAGEPLALMGQVQGLVHVLEYLDAIRGKV
MSALIKERPSADAVLAKAVLAAREQLGLTQLELAGIVGVDRSAISRWKTQGLRVDSKTGELALLLVRVYRALYALFGGQQ
EDMRHFLRTPNHHLAGEPLALMGQVQGLVHVLEYLDAIRGKV
Download Length: 369 bp
>AT218658 NZ_CP116071:2820287-2820345 [Escherichia coli]
CCTTGCCTTTCGGCACGTAAGAGGCTAACCTAGATTTGCCGTTCATAGATTGAGCCTCA
CCTTGCCTTTCGGCACGTAAGAGGCTAACCTAGATTTGCCGTTCATAGATTGAGCCTCA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|