Detailed information of TA system TA218520

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): ParST/RES-Xre
• Location: 3010423..3011375
• Replicon: chromosome
• Accession: NZ_CP084405
• Organism: Sphingobium sp. CFD-2

Toxin (Protein)

• Gene name: ParT
• Uniprot ID: -
• Locus tag: LDB29_RS14915
• Protein ID: WP_257554566.1
• Coordinates: 3010423..3010896 (-)
• Length: 158 a.a.

Antitoxin (Protein)

• Gene name: ParS
• Uniprot ID: -
• Locus tag: LDB29_RS14920
• Protein ID: WP_257554567.1
• Coordinates: 3010893..3011375 (-)
• Length: 161 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LDB29_RS14900	3005960..3006385	-	426	WP_257554561.1	hypothetical protein	-
LDB29_RS14905	3006528..3007922	-	1395	WP_257557044.1	HlyD family type I secretion periplasmic adaptor subunit	-
LDB29_RS14910	3007922..3010069	-	2148	WP_257554563.1	type I secretion system permease/ATPase	-
LDB29_RS14915	3010423..3010896	-	474	WP_257554566.1	RES family NAD+ phosphorylase	Toxin
LDB29_RS14920	3010893..3011375	-	483	WP_257554567.1	DUF2384 domain-containing protein	Antitoxin
LDB29_RS14925	3011916..3012221	+	306	WP_257554569.1	hypothetical protein	-
LDB29_RS14930	3012552..3012815	+	264	WP_257554571.1	type II toxin-antitoxin system VapB family antitoxin	-
LDB29_RS14935	3012812..3013276	+	465	WP_257554573.1	PIN domain-containing protein	-
LDB29_RS14940	3013335..3013631	+	297	WP_257554575.1	hypothetical protein	-
LDB29_RS14945	3013606..3015162	+	1557	WP_257554577.1	hypothetical protein	-
LDB29_RS14950	3015383..3016126	-	744	WP_257554578.1	LuxR family transcriptional regulator	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (5-151)

Antitoxin

• Antitoxin Xre-like, helix-turn-helix domain (34-93)

Sequences

Toxin

Protein

• Length: 158 a.a.
• Molecular weight: 17174.30 Da
• Isoelectric Point: 5.5595

>T218520 WP_257554566.1 NZ_CP084405:c3010896-3010423 [Sphingobium sp. CFD-2]
VSQSLWRIGTDTRSYSASDLSGTGAKLSGGRWNDEGVAVVYTASTRSLACLETVVHLAADELPLNRYLVEVVVPDDIWGG
AERLDHRTAPVGWDAHPAGIESTAYGTEWVISQRTALLFVPSTIVPEEPNVLINPAHPDAARITATKIRKWIYDHRL

Nucleotide

• Length: 474 bp

>T218520 NZ_CP116014:c1298343-1297597 [Bacillus velezensis]
ATGCTTTTGTTTTTTCAGATTATGGTGTGGACGATGGCGGCCGCACTCATTTTATATGTGTACGCATCCTGGCGGTATGA
GGCAAAGGTAAAAGAAAAAATGTTTGCCATCCGTAAAACGTGGTATTTACTATTTGTACTGGGCTCCATGGTCTATTGGA
CATATGATCCCGAATCGCTCTTTGCCGCATGGAGACAATATTTGATTGTTGCCGTCTGCTTTGCCCTTATTGATGCGTTT
ATCTTTTTGAGCGCGTATATCAAAAAGCTCGCCGGCAATGAATTAGAGACGGATACGCGGGAAATTTTAGAAGAAAATAA
CGAAATGCTTCACTCCTATCTTGAAAAACTGAAAACCTATCAATATCTGTTGAAAAATGAACCGATCCATGTATATTATG
GAAGTACAGAAGCTTATGCGGAAGGCATCAGCAGACTGCTGGCCGCTTATGCCGAAAAAATGAATGTCACGGCTTCCTTG
TGCGACTATTCCGGACAATCGGATAAGGACCGCTTGACGGAGCATATGCCTGATGCGGCAGACGTTCAGTCCCGTCTTAA
CCGAAAAGACGTCTACTATGATCAAAAAGGCAGGCTTGTGCTTATTCCGTTTACAGTCCAGAACCGCCATTACGTGATCA
AACTCACGTCGGAAAACCTGTTGACGGAATTCGATTATTTGCTTTTCACATCGCTAACGAGCATTTATGATTTAATGCTG
CCAATAGAAGAGGAAGGTGACGGTTAA

Antitoxin

Protein

• Length: 161 a.a.
• Molecular weight: 17374.29 Da
• Isoelectric Point: 10.2734

>AT218520 WP_257554567.1 NZ_CP084405:c3011375-3010893 [Sphingobium sp. CFD-2]
MMTRAGTAITTKVEAPTGNLVPIDLFRAGAAEKIAFIKKGVPARTAKYLIRGFNLDQKVMLDALSLKTATINRKATKNQV
LSADESERVIGLAELLGQVEAMVEESGNPEGFDARTWLANWLRRPVPALGGAKPLEYLDTMKGQMLVSKLLQQMQTGAFA

Nucleotide

• Length: 483 bp

>AT218520 NZ_CP116014:c1297596-1297426 [Bacillus velezensis]
ATGGAGCAGGCATTTCAAAACGGGCAGCCGGAACAAAGAGCGAAACCGTTCAAAATGTTTAAAAAACGTTCAATGACAAG
TATCGCAAGTTACCAGGTCAGCCCTCATACCGCCAGAATTTTCAAAGAAAACGAGCGGCTGATTGACAAGTATAAACAAA
AAAAAGCTTGA