Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/CC2985(antitoxin)
Location 1797639..1798176 Replicon chromosome
Accession NZ_CP084405
Organism Sphingobium sp. CFD-2

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag LDB29_RS08645 Protein ID WP_013846902.1
Coordinates 1797880..1798176 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag LDB29_RS08640 Protein ID WP_013846901.1
Coordinates 1797639..1797890 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LDB29_RS08610 1792663..1793310 - 648 WP_013846895.1 hypothetical protein -
LDB29_RS08615 1793386..1794081 - 696 WP_013846896.1 hypothetical protein -
LDB29_RS08620 1794223..1795032 - 810 WP_013846897.1 type I restriction-modification system subunit M -
LDB29_RS08625 1795199..1796446 - 1248 WP_013846898.1 hypothetical protein -
LDB29_RS08630 1796634..1796939 - 306 WP_013846899.1 hypothetical protein -
LDB29_RS08635 1796936..1797412 - 477 WP_013846900.1 hypothetical protein -
LDB29_RS08640 1797639..1797890 + 252 WP_013846901.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
LDB29_RS08645 1797880..1798176 + 297 WP_013846902.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 1603504..1818712 215208


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-91)

Antitoxin

Antitoxin ParD

(6-75)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 10941.43 Da        Isoelectric Point: 6.8785

>T218518 WP_013846902.1 NZ_CP084405:1797880-1798176 [Sphingobium sp. CFD-2]
MAYRLTRNAEKDLIGIYVGGVGELGEAVAEKYQAGLHRVFGFLSDFPYSARARAEISPPVRAHPYKSHIVVYIIEGQDIL
ILGVRHGREDWQASDQLS

Download         Length: 297 bp

>T218518 NZ_CP116013:3635490-3635840 [Bacillus velezensis]
TTGATTGTGAAACGCGGCGATGTTTATTTTGCTGATTTATCTCCTGTTGTTGGCTCAGAGCAAGGCGGGGTGCGCCCGGT
CTTAGTGATCCAAAATGACATCGGAAATCGCTTCAGCCCAACTGCTATTGTTGCAGCCATAACAGCACAAATACAGAAAG
CGAAATTACCAACCCACGTCGAAATCGATGCAAAACGCTACGGTTTTGAAAGAGATTCCGTTATTTTGCTGGAGCAAATT
CGGACGATTGACAAGCAAAGGTTAACGGATAAGATTACTCATCTGGATGATGAAATGATGGATAAGGTTGATGAAGCCTT
ACAAATCAGTTTGGCACTCATTGATTTTTAG

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9230.40 Da        Isoelectric Point: 5.8295

>AT218518 WP_013846901.1 NZ_CP084405:1797639-1797890 [Sphingobium sp. CFD-2]
MATMNVSLPDAMKEWVEGQAGTGRYSNASDYVRDLIRRDQERREKIAAMQTMVDESLASGISPNSIDDMMKEARRRAGVG
HGL

Download         Length: 252 bp

>AT218518 NZ_CP116013:3635204-3635485 [Bacillus velezensis]
TTGTCTGAATCCAGCGCAAGAACCGAAATGAAAATCAGCTTGCCCGAAAACCTAGTAGCTGAATTGGATGGTGTAGCGAT
GCGGGAGAAACGAAGCAGAAACGAACTGATATCACAAGCAGTGAGAGCATATGTCAGCGAACGAACAACTCGCCATAACC
GTGATTTGATGAGACGCGGCTATATGGAAATGGCGAAAATCAACCTGAATATTTCTTCTGAGGCTCACTTTGCGGAGTGC
GAGGCTGAAACGACAGTTGAGCGCTTAGTCAGCGGAGGATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References