Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 899336..899907 Replicon chromosome
Accession NZ_CP084398
Organism Sphingobium sp. CFD-1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LDB26_RS04545 Protein ID WP_257540668.1
Coordinates 899617..899907 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LDB26_RS04540 Protein ID WP_257540666.1
Coordinates 899336..899617 (-) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LDB26_RS04490 894945..895124 + 180 WP_257540644.1 hypothetical protein -
LDB26_RS04495 895124..895696 + 573 WP_257540646.1 head-tail connector protein -
LDB26_RS04500 895690..896040 + 351 WP_257540649.1 phage head closure protein -
LDB26_RS04505 896037..896597 + 561 WP_257540650.1 HK97 gp10 family phage protein -
LDB26_RS04510 896597..897004 + 408 WP_257540653.1 DUF3168 domain-containing protein -
LDB26_RS04515 897006..897173 + 168 WP_257540655.1 hypothetical protein -
LDB26_RS04520 897242..897709 + 468 WP_257540657.1 hypothetical protein -
LDB26_RS04525 897787..898239 + 453 WP_257540659.1 hypothetical protein -
LDB26_RS04530 898299..898649 + 351 WP_257540662.1 hypothetical protein -
LDB26_RS04535 898744..899310 + 567 WP_257540664.1 NUMOD4 motif-containing HNH endonuclease -
LDB26_RS04540 899336..899617 - 282 WP_257540666.1 putative addiction module antidote protein Antitoxin
LDB26_RS04545 899617..899907 - 291 WP_257540668.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LDB26_RS04550 900829..904245 + 3417 WP_257540671.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 868334..949139 80805


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-95)

Antitoxin

Cro/C1-type helix-turn-helix domain

(46-90)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10746.54 Da        Isoelectric Point: 9.9002

>T218510 WP_257540668.1 NZ_CP084398:c899907-899617 [Sphingobium sp. CFD-1]
MKTIKTTAVYDNWIEGLRDRQAVARIRIRIDRLAMGNRGDHRNLKAGVVELKIDFGPGYRVYCTERAGEIVILLCGGTKK
GQDADIALAEKMAKEL

Download         Length: 291 bp

>T218510 NZ_CP116011:434621-434971 [Bacillus amyloliquefaciens]
TTGATTGTAAAGCGCGGCGATGTTTATTTTGCTGATTTATCTCCTGTTGTTGGCTCAGAGCAAGGCGGCGTACGCCCGGT
TTTAGTGATCCAAAATGATATCGGAAATCGCTTTAGCCCAACTGCTATTGTTGCAGCCATAACAGCCCAAATACAGAAAG
CGAAATTACCAACCCACGTCGAAATTGATGCAAAACGCTACGGTTTTGAAAGAGATTCCGTTATTTTGCTGGAGCAAATT
CGGACGATTGACAAGCAAAGATTAACGGATAAAATAACTCATCTGGATGATGAAATGATGGATAAGGTTGATGAAGCCCT
GCAAATCAGTTTGGCACTCATTGATTTTTAG

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10127.60 Da        Isoelectric Point: 4.8228

>AT218510 WP_257540666.1 NZ_CP084398:c899617-899336 [Sphingobium sp. CFD-1]
MAIELKNYDVAEHLSNDEEIRLYLEAAFEDGDPAIIKNAISNVVRARGMTAMAKESGVSRETLYKAFAENGNPTLDTLMK
VTKALGVRLAIAA

Download         Length: 282 bp

>AT218510 NZ_CP116011:434334-434615 [Bacillus amyloliquefaciens]
TTGTCTGAATCCAGCGCAAGAACCGAAATGAAAATCAGCTTGCCTGAAAACTTAGTAGCTGAATTGGATGGTGTAGCGAT
GCGGGAGAAACGAAGCAGAAACGAACTGATATCACAGGCAGTGAGAGCGTATGTCAGCGAACGGACAACTCGCCATAACC
GTGATTTGATGAGACGCGGGTATATGGAAATGGCGAAAATCAACTTGAATATTTCTTCTGAGGCTCACTATGCTGAGTGC
GAAGCAGAAACGACGGTTGAGCGCTTAGTCAGCGGAGGATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References