Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2020180..2020325 | Replicon | chromosome |
| Accession | NZ_CP084397 | ||
| Organism | Klebsiella pneumoniae subsp. pneumoniae strain MRSN752019 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2020216..2020318 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2020180..2020325 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KF608_RS12445 | 2015310..2017370 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| KF608_RS12450 | 2017374..2018033 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| KF608_RS12455 | 2018112..2018342 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| KF608_RS12460 | 2018455..2018829 | + | 375 | WP_039819395.1 | CopC domain-containing protein YobA | - |
| KF608_RS12465 | 2018833..2019702 | + | 870 | WP_004175431.1 | copper homeostasis membrane protein CopD | - |
| KF608_RS12470 | 2019719..2020057 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 2020180..2020325 | - | 146 | - | - | Antitoxin |
| - | 2020216..2020318 | + | 103 | - | - | Toxin |
| KF608_RS12475 | 2020694..2020837 | - | 144 | WP_038431282.1 | Ecr family regulatory small membrane protein | - |
| KF608_RS12480 | 2020942..2021910 | - | 969 | WP_014907334.1 | VirK/YbjX family protein | - |
| KF608_RS12485 | 2022067..2022720 | + | 654 | WP_024622748.1 | protein-serine/threonine phosphatase | - |
| KF608_RS12490 | 2022717..2022908 | - | 192 | WP_002911395.1 | YebW family protein | - |
| KF608_RS12495 | 2023006..2023245 | - | 240 | WP_002911393.1 | YebV family protein | - |
| KF608_RS12500 | 2023361..2024794 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T218496 NZ_CP084397:2020216-2020318 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT218496 NZ_CP084397:c2020325-2020180 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
