Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2324965..2325059 Replicon chromosome
Accession NZ_CP084336
Organism Yersinia pestis strain R

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2324966..2325059 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2324965..2325059 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LDH64_RS10595 (LDH64_10585) 2320158..2322236 - 2079 WP_002211100.1 flagellar biosynthesis protein FlhA -
LDH64_RS10600 (LDH64_10590) 2322236..2323396 - 1161 WP_002211099.1 flagellar biosynthesis protein FlhB -
LDH64_RS10605 (LDH64_10595) 2323928..2324386 + 459 WP_002211098.1 hypothetical protein -
LDH64_RS10610 (LDH64_10600) 2324380..2324706 + 327 WP_002211097.1 DUF1493 family protein -
- 2324965..2325059 + 95 - - Antitoxin
- 2324966..2325059 - 94 - - Toxin
LDH64_RS10615 (LDH64_10605) 2325229..2325570 - 342 WP_002211095.1 YebY family protein -
LDH64_RS10620 (LDH64_10610) 2325667..2326551 - 885 WP_002211094.1 copper homeostasis membrane protein CopD -
LDH64_RS10625 (LDH64_10615) 2326554..2326940 - 387 WP_002211093.1 CopC domain-containing protein YobA -
LDH64_RS10630 (LDH64_10620) 2327337..2327846 - 510 WP_002211092.1 non-heme ferritin -
LDH64_RS10635 (LDH64_10625) 2328247..2328477 + 231 WP_002211091.1 DNA polymerase III subunit theta -
LDH64_RS10640 (LDH64_10630) 2328537..2329487 - 951 WP_002211090.1 prolyl aminopeptidase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 94 bp

>T218438 NZ_CP084336:c2325059-2324966 [Yersinia pestis]
TAAGCCTACATTAATACCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTAGACCGAATATCAGGAATCGTA
TTCGGTCTTTTTTT

Antitoxin


Download         Length: 95 bp

>AT218438 NZ_CP084336:2324965-2325059 [Yersinia pestis]
TAAAAAAAGACCGAATACGATTCCTGATATTCGGTCTAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGT
ATTAATGTAGGCTTA

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References