Detailed information of TA system TA218413

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 433132..433768
• Replicon: chromosome
• Accession: NZ_CP084300
• Organism: Acinetobacter pseudolwoffii strain XMC5X702

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: N9MD45
• Locus tag: LDO52_RS02120
• Protein ID: WP_005094124.1
• Coordinates: 433382..433768 (+)
• Length: 129 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: N9M562
• Locus tag: LDO52_RS02115
• Protein ID: WP_005094125.1
• Coordinates: 433132..433389 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LDO52_RS02095 (LDO52_02095)	428612..429619	+	1008	WP_005094131.1	DNA-directed RNA polymerase subunit alpha	-
LDO52_RS02100 (LDO52_02100)	429638..430003	+	366	WP_004281488.1	50S ribosomal protein L17	-
LDO52_RS02105 (LDO52_02105)	430225..431715	+	1491	WP_225553644.1	NAD(P)/FAD-dependent oxidoreductase	-
LDO52_RS02110 (LDO52_02110)	431776..432948	-	1173	WP_225553646.1	acyl-CoA dehydrogenase family protein	-
LDO52_RS02115 (LDO52_02115)	433132..433389	+	258	WP_005094125.1	succinate dehydrogenase assembly factor 2	Antitoxin
LDO52_RS02120 (LDO52_02120)	433382..433768	+	387	WP_005094124.1	hypothetical protein	Toxin
LDO52_RS02125 (LDO52_02125)	434305..435345	+	1041	WP_005094123.1	hypothetical protein	-
LDO52_RS02130 (LDO52_02130)	435413..435985	+	573	WP_005168711.1	rhombosortase	-
LDO52_RS02135 (LDO52_02135)	436183..438465	+	2283	WP_159516279.1	TRAP transporter large permease subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (10-80)

Sequences

Toxin

Protein

• Length: 129 a.a.
• Molecular weight: 15190.27 Da
• Isoelectric Point: 9.4014

>T218413 WP_005094124.1 NZ_CP084300:433382-433768 [Acinetobacter pseudolwoffii]
MDNRCFKLKRSYCALAFQLFIFALLMYLLYQLLPIAIWLLCAAIGLVIYQLFYRKTPQIEQFEYLDGREWSLTAKSRPTC
RVCVSHVIDHQAYIVVYFQHAKAQPLLIWCDQLPLKQWKSLKVLTKLI

Nucleotide

• Length: 387 bp

>T218413 NZ_CP115941:c997995-997741 [Ralstonia syzygii]
ATGAAAGCCAAACACCAGAAGACGCTGGAGCTGATCTTTTCCCGCCCTACGCCAGCGGGCGTTAAGTGGGCCGATGCCGT
CACGCTCATGCGAGAACTGGGCGCGGAATTGGAGGAGCGCGAGGGTTCTCGCGTGGCCGTCTTCCTGTTTGGTCAAGTTA
AAGTGATGCATCGACCACACCCATCGCCCGATATGGACAAGGGCGCTGTGGCCTCGATGCGTAAGTGGTTCGAGGAAAAC
GGAGTCAAGCCATGA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 10305.81 Da
• Isoelectric Point: 4.4606

>AT218413 WP_005094125.1 NZ_CP084300:433132-433389 [Acinetobacter pseudolwoffii]
MTDDITLEERKVIYRARRGLKELDVYFDPYVKNYYLTADPFEKQMFAELVDQEDPDLLDWFMEVSEPPRPELKDLIKKLK
FYVHG

Nucleotide

• Length: 258 bp

>AT218413 NZ_CP115941:c997744-997406 [Ralstonia syzygii]
ATGATCAACGTCATGAACATCGGCGGCCACAAGGCCGTCATCGCCTACGACCCGGATATCGAAATGTTCCGTGGCGAGTT
TGTTGGCCTGAACGGTGGCGCCGACTTCTACGCCGCCGATGTGACCGGCCTGCACCGCGAAGGTGAGTTGTCGCTGCGCG
TGTTTCTGGAAGAGTGCGCACGGCGTGGCGTTGAGCCGCAAAAGCACTTTTCCGGCAAGTTCGTGCTGCGCGTGGAGGGC
AAGGTGCACGAGGCCGCCGCCATCGCCGCTGCCGCGCAAGGCGTGAGCCTTAACCAGTGGGCAGCCGGCGTGCTGGAGCA
AGCCGCCGAGGCGGCTTAA

Structures

Toxin

• AlphaFold DB: N9MD45

Antitoxin

• AlphaFold DB: N9M562