Detailed information of TA system TA218410

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 469299..469952
• Replicon: chromosome
• Accession: NZ_CP084297
• Organism: Acinetobacter baumannii strain LHC22-2

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: LDO71_RS02250
• Protein ID: WP_225546105.1
• Coordinates: 469563..469952 (+)
• Length: 130 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: V5V966
• Locus tag: LDO71_RS02245
• Protein ID: WP_001288210.1
• Coordinates: 469299..469556 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LDO71_RS02225 (LDO71_02225)	464815..465822	+	1008	WP_000198631.1	DNA-directed RNA polymerase subunit alpha	-
LDO71_RS02230 (LDO71_02230)	465841..466218	+	378	WP_001216380.1	50S ribosomal protein L17	-
LDO71_RS02235 (LDO71_02235)	466400..467890	+	1491	WP_000415132.1	NAD(P)/FAD-dependent oxidoreductase	-
LDO71_RS02240 (LDO71_02240)	467939..469111	-	1173	WP_225546104.1	acyl-CoA dehydrogenase family protein	-
LDO71_RS02245 (LDO71_02245)	469299..469556	+	258	WP_001288210.1	succinate dehydrogenase assembly factor 2	Antitoxin
LDO71_RS02250 (LDO71_02250)	469563..469952	+	390	WP_225546105.1	hypothetical protein	Toxin
LDO71_RS02255 (LDO71_02255)	470721..471806	+	1086	WP_163048110.1	hypothetical protein	-
LDO71_RS02260 (LDO71_02260)	471884..472450	+	567	WP_000651536.1	rhombosortase	-
LDO71_RS02265 (LDO71_02265)	472638..474833	+	2196	WP_225546106.1	TRAP transporter large permease subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (10-82)

Sequences

Toxin

Protein

• Length: 130 a.a.
• Molecular weight: 15511.77 Da
• Isoelectric Point: 10.3889

>T218410 WP_225546105.1 NZ_CP084297:469563-469952 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAALFYQLMPLLWLLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYQSQNTV
SRVKILKIIDYQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Nucleotide

• Length: 390 bp

>T218410 NZ_CP115931:c32586-32170 [Klebsiella pneumoniae subsp. pneumoniae]
GTGAACAAGACCTATATGCTCGACACCTGTATCTGCTCGTTCATCATGCGCGAGCAGCCGGAAGCCGTCCTGAAGCGCCT
GGAGCAGGCGGTGCTGCGCGGCCAGCGCATCGTTGTCTCGGCCATCACTTATTCTGAAATGCGCTTCGGGGCCACCGGCC
CGAAGGCCTCCCCGCGCCACGTCGAGCTGGTCGACGCGTTCTGCGCCCGCCTCGATGCCATCCTGCCCTGGGATCGCGCT
GCGGTGGACGCCACCACGGAGATTAAGGTGGCGCTGCGAATGGCCGGGACGCCGATCGGCCCGAACGACACGGCCATTGC
CGGGCACGCCATCGCCGCCGGTGCCGTGCTGGTGACGAATAATACGCGGGAATTTGAGCGGGTACCGGGTCTTGTGCTGG
AAGACTGGGTAAGATAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 10318.77 Da
• Isoelectric Point: 4.6150

>AT218410 WP_001288210.1 NZ_CP084297:469299-469556 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Nucleotide

• Length: 258 bp

>AT218410 NZ_CP115931:c32813-32583 [Klebsiella pneumoniae subsp. pneumoniae]
ATGAGAACTGTATCCATTTTTAAAAACGGCAATAACCGCGCCATTCGTCTGCCCCGCGATCTGGATTTTGAGGGAGTGAG
CGAGCTGGAGATCGTCCGGGAAGGGGACAGCATTATTTTGCGTCCCGTCCGGCCGACCTGGGGCTCGTTCGCGCAGTTCG
AGAAGGCAGACCCGGACTTTATGGCGGAGCGCGAGGACGTTGTCAGCGACGAAGGACGATTTAACCTGTGA

Structures

Antitoxin

• AlphaFold DB: A0A7U4BQM7