Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 446092..446549 Replicon chromosome
Accession NZ_CP084252
Organism Caballeronia sp. Sq4a

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LDZ24_RS21645 Protein ID WP_248324246.1
Coordinates 446092..446307 (-) Length 72 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LDZ24_RS21650 Protein ID WP_248324136.1
Coordinates 446355..446549 (-) Length 65 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LDZ24_RS21610 441519..443113 - 1595 Protein_406 IS66 family transposase -
LDZ24_RS21615 443144..443488 - 345 WP_248324132.1 IS66 family insertion sequence element accessory protein TnpB -
LDZ24_RS21620 443485..443832 - 348 WP_241484933.1 transposase -
LDZ24_RS21625 443987..444663 - 677 Protein_409 HAMP domain-containing protein -
LDZ24_RS21630 444741..444956 - 216 WP_248324133.1 DUF3717 domain-containing protein -
LDZ24_RS21635 444940..445341 - 402 WP_248324134.1 hypothetical protein -
LDZ24_RS21640 445406..445789 - 384 WP_248324135.1 hypothetical protein -
LDZ24_RS21645 446092..446307 - 216 WP_248324246.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LDZ24_RS21650 446355..446549 - 195 WP_248324136.1 antitoxin Antitoxin
LDZ24_RS21655 447209..447931 - 723 WP_248324137.1 hypothetical protein -
LDZ24_RS21660 448178..448459 - 282 WP_248324138.1 DNA-binding protein -
LDZ24_RS21665 448656..449027 - 372 WP_248324139.1 type II toxin-antitoxin system RelE/ParE family toxin -
LDZ24_RS21670 448976..449245 - 270 WP_248324140.1 ribbon-helix-helix protein, CopG family -
LDZ24_RS21675 449436..450335 - 900 WP_248324141.1 LysR family transcriptional regulator -
LDZ24_RS21680 450444..451307 + 864 WP_248324142.1 aldo/keto reductase family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-70)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 72 a.a.        Molecular weight: 8296.57 Da        Isoelectric Point: 9.4526

>T218371 WP_248324246.1 NZ_CP084252:c446307-446092 [Caballeronia sp. Sq4a]
IEEDNPAAADFVFEALIAAAASLPDHPYVYREGRKPNTREMVVMPNYIIVYRVKRDRIQIVNVLHARRRYP

Download         Length: 216 bp

>T218371 NZ_CP115887:c2171343-2171134 [Staphylococcus aureus]
ATGATACATCAAAATACGATTTACACAGCGGGAATTGAAACAGAAGAACAAGTAAGTCAATTGACAGAACGCATTTCAAA
TATGATAGGTGTTCATCAAGTGAATATTAATATAATAGACGGTCAAGTAACTGTATCGTATGAGACACCAGCAAATTTGA
ATAGTATTGAAAAAGAAATCTATGATGAAGGATACAAAATTGTATTTTAG

Antitoxin


Download         Length: 65 a.a.        Molecular weight: 7404.15 Da        Isoelectric Point: 4.8380

>AT218371 WP_248324136.1 NZ_CP084252:c446549-446355 [Caballeronia sp. Sq4a]
MGNIWTEPAVSGHDTKEEAEAYDDWFRKEVQLALDEKGEDIPHDQVVAEMRAHIEAKRRARNGR

Download         Length: 195 bp

>AT218371 NZ_CP115887:c2171648-2171355 [Staphylococcus aureus]
ATGACTGAACAAGATATTGCACATCATTCTGAACAAATAAAAACGAATCTTAAATCACGTTTAAATCGAATTGAAGGACA
AGTGAGAGCGATTAATCGCATGATTGAAGAAGATGTCTATTGTGATGATGTCCTTACGCAAATAAGAGCGACACGTTCGG
CGTTAAACAGTGTTGCGACAAAGTTATTAGAACAACATATGAAAAGTTGTATTATGAATAAAGTTAATCAAGGTGCTCAG
GAAGAGGCAATGGAAGAGTTATTAGTGACTTTTCAAAAATTGATTAAAGACTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References