21837

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) omega-epsilon-zeta/-
Location 3373402..3374957 Replicon chromosome
Accession NC_008752
Organism Acidovorax citrulli AAC00-1

Toxin (Protein)


Gene name avrRxo1 Uniprot ID -
Locus tag AAVE_RS15320 Protein ID WP_011796138.1
Coordinates 3373402..3374646 (+) Length 415 a.a.

Antitoxin (Protein)


Gene name arc1 Uniprot ID A1TRP1
Locus tag AAVE_RS15325 Protein ID WP_011796139.1
Coordinates 3374661..3374957 (+) Length 99 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AAVE_RS15305 (Aave_3059) 3369296..3369634 - 339 WP_011796135.1 hypothetical protein -
AAVE_RS15310 (Aave_3060) 3369950..3370912 - 963 WP_011796136.1 FHA domain-containing protein -
AAVE_RS15315 (Aave_3061) 3370938..3373142 - 2205 WP_041828059.1 TOMM precursor leader peptide-binding protein -
AAVE_RS15320 (Aave_3062) 3373402..3374646 + 1245 WP_011796138.1 zeta toxin family protein Toxin
AAVE_RS15325 (Aave_3063) 3374661..3374957 + 297 WP_011796139.1 hypothetical protein Antitoxin
AAVE_RS15330 (Aave_3064) 3375116..3375979 - 864 WP_011796140.1 class I SAM-dependent methyltransferase -
AAVE_RS15335 (Aave_3065) 3375980..3376777 - 798 WP_011796141.1 BMA_0021/BMA_0022 family TOMM bacteriocin -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(145-284)

Antitoxin


No domain identified.



Sequences


Toxin        


Download         Length: 415 a.a.        Molecular weight: 44326.94 Da        Isoelectric Point: 8.6793

>T21837 WP_011796138.1 NC_008752:3373402-3374646 [Acidovorax citrulli AAC00-1]
MTDRLSRRNSANSTPRPVTSNAASISRHETPPRPTSRPVHALPAGFPAPSQRSRSSSPSRVRASLPAKVPETSGNRPAIR
LPAAPRGSDEIFGLGELPPPGQSRWDYLAHPQNWRPERRQLHDRLIGDAKTAAQDFAEVIERGGHPPTLFALRGNTAAGK
TRMATQTIPVLANALKESGGAGCINPDIFKRSLAETPEGAKLTSAQVHAESCILADRLEDELRLQKTASGAAISMLVDKR
LAGAHEIDAYIKLAQETGRKIELCDIDAPLEQSLMGVLQRKPEGDAPRPPYVAVANGFSAVRGHRLDVIDKFLSNPTLGS
YHLFGTTGNGSKAMVASVVNGELSIHDPQLYEAITDPQGARAGDSGDQIIDAALIDRLTKGIDDPARAMDARTALERYAG
MTWSDALAAHSSLT

Download         Length: 1245 bp

>T21837 NC_008752:3373402-3374646 [Acidovorax citrulli AAC00-1]
ATGACAGACAGACTCAGCCGGCGAAATTCAGCGAATTCAACGCCCCGGCCCGTGACCAGCAACGCCGCTTCGATCAGCCG
GCATGAAACGCCACCGCGCCCGACCTCCCGTCCGGTGCATGCGCTGCCAGCCGGCTTCCCGGCACCATCGCAGAGATCGC
GCAGTTCATCGCCTTCACGGGTCAGGGCCTCACTGCCGGCAAAAGTGCCGGAGACATCGGGCAACAGGCCTGCGATCCGT
TTGCCGGCCGCACCCAGGGGGTCGGACGAGATCTTCGGCCTGGGGGAACTCCCTCCTCCTGGCCAGTCCCGATGGGACTA
TTTGGCCCATCCTCAAAACTGGCGCCCCGAGCGGCGTCAATTGCATGACCGGCTGATCGGCGATGCGAAAACTGCAGCCC
AGGATTTCGCCGAGGTGATCGAGCGCGGTGGCCACCCACCGACATTGTTCGCGTTGCGAGGCAATACGGCTGCGGGAAAG
ACACGCATGGCGACACAAACCATCCCCGTACTCGCCAATGCCCTCAAGGAGAGTGGCGGCGCCGGCTGTATTAATCCCGA
CATCTTCAAACGTTCGCTCGCAGAAACTCCAGAGGGAGCAAAACTTACCTCGGCGCAGGTACACGCCGAGTCGTGCATCC
TCGCTGACCGGCTTGAAGACGAACTCCGATTGCAGAAGACCGCGAGCGGCGCGGCGATCAGCATGCTGGTCGATAAGCGA
CTGGCTGGAGCGCACGAAATCGACGCGTACATCAAGCTGGCTCAGGAGACCGGTCGCAAAATCGAGTTGTGCGATATTGA
TGCTCCACTCGAGCAGTCACTCATGGGCGTGCTGCAGCGCAAGCCCGAAGGTGACGCCCCCCGGCCACCCTACGTTGCGG
TTGCCAACGGATTCTCGGCGGTTCGCGGGCACCGGCTCGATGTCATCGACAAGTTTCTCTCGAACCCGACCTTGGGGAGC
TATCATCTATTCGGCACTACCGGGAATGGCAGCAAGGCGATGGTTGCCAGCGTCGTCAACGGCGAACTGAGCATTCATGA
CCCTCAGTTATACGAGGCCATTACAGATCCCCAAGGTGCCCGGGCAGGCGATAGCGGCGATCAGATCATTGACGCTGCGC
TGATCGACCGGCTGACCAAAGGTATAGACGACCCAGCGCGAGCCATGGATGCCCGCACCGCATTGGAGCGGTACGCGGGC
ATGACGTGGTCGGACGCTCTGGCCGCCCATAGTTCACTGACTTGA

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 11106.62 Da        Isoelectric Point: 6.9795

>AT21837 WP_011796139.1 NC_008752:3374661-3374957 [Acidovorax citrulli AAC00-1]
MTGLKGADALDFHKKLKERNAALRNAELNAAKELADKNGKEPFDLVKLERLCDTSQAGRLVEGTERQAMYEYMYYVEYKN
VGTLQDFARVVTTLASWS

Download         Length: 297 bp

>AT21837 NC_008752:3374661-3374957 [Acidovorax citrulli AAC00-1]
ATGACAGGCCTGAAAGGCGCAGATGCGCTCGACTTCCATAAGAAACTCAAGGAACGCAATGCTGCTTTACGCAATGCGGA
GTTGAACGCGGCGAAGGAACTGGCCGACAAAAATGGCAAGGAGCCTTTTGATCTCGTGAAACTGGAGAGGCTTTGCGATA
CCAGTCAAGCAGGCCGCCTTGTTGAAGGGACCGAACGGCAAGCCATGTACGAATACATGTACTACGTCGAGTACAAGAAT
GTTGGCACGTTGCAGGATTTCGCCCGGGTGGTGACAACGCTCGCGTCCTGGTCTTAA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure
AlphaFold DB A1TRP1

References