Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tsbAT/-
Location 970362..971133 Replicon chromosome
Accession NZ_CP084235
Organism Staphylococcus haemolyticus strain SE2.14

Toxin (Protein)


Gene name tsbT Uniprot ID -
Locus tag RES5_RS04925 Protein ID WP_141738627.1
Coordinates 970984..971133 (+) Length 50 a.a.

Antitoxin (Protein)


Gene name tsbA Uniprot ID -
Locus tag RES5_RS04920 Protein ID WP_161511415.1
Coordinates 970362..970961 (+) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RES5_RS04900 (RES5_004900) 966236..967690 + 1455 WP_161511412.1 ABC transporter substrate-binding protein/permease -
RES5_RS04905 (RES5_004905) 967683..968405 + 723 WP_161511413.1 amino acid ABC transporter ATP-binding protein -
RES5_RS04910 (RES5_004910) 968592..969719 + 1128 WP_161511414.1 tRNA epoxyqueuosine(34) reductase QueG -
RES5_RS04915 (RES5_004915) 969720..970190 + 471 WP_053025428.1 tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL -
RES5_RS04920 (RES5_004920) 970362..970961 + 600 WP_161511415.1 glucosamine-6-phosphate isomerase Antitoxin
RES5_RS04925 (RES5_004925) 970984..971133 + 150 WP_141738627.1 SAS053 family protein Toxin
RES5_RS04930 (RES5_004930) 971343..971738 + 396 WP_161511416.1 hypothetical protein -
RES5_RS04935 (RES5_004935) 971943..973328 + 1386 WP_161511417.1 class II fumarate hydratase -
RES5_RS04940 (RES5_004940) 973394..974218 - 825 WP_085060648.1 RluA family pseudouridine synthase -
RES5_RS04945 (RES5_004945) 974406..975515 + 1110 WP_161511418.1 GAF domain-containing sensor histidine kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Glucosamine-6-phosphate isomerase

(130-195)


Sequences

Toxin        


Download         Length: 50 a.a.        Molecular weight: 5824.20 Da        Isoelectric Point: 3.9484

>T218343 WP_141738627.1 NZ_CP084235:970984-971133 [Staphylococcus haemolyticus]
MTKNKDSELNYHEEENAMVQDLDDLKTLGKEMEQISEENDEDRLNQSHE

Download         Length: 150 bp

>T218343 NZ_CP115842:2128844-2130085 [Agrobacterium fabacearum]
ATGACAACCATCTACTACGAGACCTTGCCTGTCGCCCATCTGACTTTTGAAGGCGAATGGAGGTTGGACTATGATCCGGG
CTGGGAAGCGCGCCGCCCGGCCTTTCCGGTGTCGCTTACCATGCCGCTGCGTTCCGGATCCGTAGGTGCAGCGAAGCTGC
TTCCCTGGCTTGCCAATCTGCTTCCGGAAACCCATCTTGCCGAGATCGGTCAGCGCTTCAAGGTTTCCCCGCAAGATATT
GTCGGTCTACTTGCTCATATCGGACGTGACACGGCGGGGGCACTGTCGATCGGGGAGCCGCGCAAAGCTGGCGTCAACCT
CCGGCCGGTGCCGGACGAGCAGGCGCTGGAGCGTATTCTCAATGAACTTCCTGCCAAACCCTTTCTGGTCGGAGAGCGCG
GTGTTTCCATGTCGCTTGCTGGCGTCCAGGAGAAACTGCCGGTGTTTGTTGACGGGAACGGCCGTATTTCAGTTCCGGTT
GATGGGACGCCATCCACGCATATTCTCAAGCCGGATACGAAACGCCTTGCGGGGAGCGTGGAGAACGAAGCCTTTTGCCT
GTCGCTTGCACGTGCCTGCGGTCTTGAGGCTGCCGAGGCGACGATCGGAGTAGCTGGCAAGCGGCGTTATCTTCTCGTGA
AACGCTATGATCGCTTCACCGACCCTCAAGGCGAGATCCGCAGGTTGCATCAGGAGGATCTTTGCCAGTTAACCGGTTGC
TTCCCCTCGCAGAAATACGAGCGATCCTCGACCGGCCGCGGCGTGACCATGAAGATGATGTTTGACGCCGTCAGCGATCT
TGTTTCGCCTGGCGAGCGGTTGAAACTTCTCGATGCGGTGATCTTCAATGTCCTGATCTGCAATTCGGATTCGCATGCCA
AAAATTACTCTATCCTGATTGGTGCCGGTGGGTCCGCGAAGATGGCTCCACTCTATGACCTGATGTGCGCTGCCGTTTAT
CGCCAGGTCGACCAGAGCCTGCCGCAGGGGATTTTCGGTCGGTTCCATGCGCCTGACCTGCGGCGTGCCGACTGGCAGGC
ACTGGCTGATGACATTGGATTGAGCGGCGCATCGACACTGAAACGGGTGGGGGAGCTTGCAAAACTGGTCAGCGTCGCAT
GCGATGAGGTGGCACCATATATCGTCGCCCTCTCCAGCGATCCGACGAGGATTCTTGAGCGAATTACTCACAGCGTTCAA
AAGCGGTGCCGGCGAATTCAGGAGCAGATGCATGATCGATGA

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22256.12 Da        Isoelectric Point: 4.7588

>AT218343 WP_161511415.1 NZ_CP084235:970362-970961 [Staphylococcus haemolyticus]
MAMNFKVFNDVEHVAEYTADIIRKQFNNNPTTIAGIHLTKDAAPVLDELKKDVDHNAVDFSQVNILDYDDNRSYYEALGV
PASQIYPINLDDDAESLIDDKIKTKENKGKLILQVTSIDESGSLNVNVRQGLLKAREVVLVVTGANKREVVKKLYEENGK
SSFEPADLKAHRMVTVVLDRAAAEGLPEDVKEYFTARFA

Download         Length: 600 bp

>AT218343 NZ_CP115842:2128575-2128847 [Agrobacterium fabacearum]
ATGTTCAGGTCCGCGCGTGATTTCGGCGCTGCTATCAAGGAGAGACGCAAAGCACTTGGCTGGACGCAAACCGGTCTTGC
TGCCCGTTCCGGAACGGGGGAACGCTTCATCGTCGAGCTTGAATCGGGCAAGCCGAGTTGCCAGCTCGAAAAAGCCCTGA
TCGTCGCACGCGCAGTTGGAATCGATCTTGGCGATCTCAAGACGGTTCAGACTGTGCAAGTCGCGTCGGACGATGACCTC
GGCTTTTTGCCGATGTTTGGTGCTGATCAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References